Module 1 - Introduction to Developmental Biology Flashcards
Brian Key
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1593384790 | Developmental Biology | Organisation of cells into functional units through spatial and temporal gene expression in specific microenvironments L2 | 0 | |
1593384791 | Major Driving Force for Development | Differential gene expression in both time and space L2 | 1 | |
1593384792 | Repressed State | Default state of genes where genes are present in chromatin consisting of DNA and protein L2 | 2 | |
1593384793 | Primary Germ Layers (3) | Ectoderm Mesoderm Endoderm L2 | 3 | |
1593384794 | Induction | Group of cells/tissue become committed - involves inducers L2 | 4 | |
1593384795 | Regionalisation | Formation of decentralised tissue regions - involves morphogens L2 | 5 | |
1593384796 | Differentiation | Production of specific cell types/phenotypes within regions - involves growth factors L2 | 6 | |
1593384797 | C. elegans and Developmental Biology | Highly regulated developmental process results in defined cell number which allows for construction of lineage tree L2 | 7 | |
1593384798 | Preimplantation Genetic Diagnosis (PGD) | Widely used technique for couples at genetic risk involving diagnosis and transfer of unaffected embryos generated through in vitro fertilisation (IVF) techniques L2 | 8 | |
1593384799 | Blastomere Biopsy | Use needle to remove single blastomere during early development to perform genetic analysis - other blastomeres can replicate to replace it L2 | 9 |