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Module 1 - Introduction to Developmental Biology Flashcards

Brian Key

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1593384790Developmental BiologyOrganisation of cells into functional units through spatial and temporal gene expression in specific microenvironments L20
1593384791Major Driving Force for DevelopmentDifferential gene expression in both time and space L21
1593384792Repressed StateDefault state of genes where genes are present in chromatin consisting of DNA and protein L22
1593384793Primary Germ Layers (3)Ectoderm Mesoderm Endoderm L23
1593384794InductionGroup of cells/tissue become committed - involves inducers L24
1593384795RegionalisationFormation of decentralised tissue regions - involves morphogens L25
1593384796DifferentiationProduction of specific cell types/phenotypes within regions - involves growth factors L26
1593384797C. elegans and Developmental BiologyHighly regulated developmental process results in defined cell number which allows for construction of lineage tree L27
1593384798Preimplantation Genetic Diagnosis (PGD)Widely used technique for couples at genetic risk involving diagnosis and transfer of unaffected embryos generated through in vitro fertilisation (IVF) techniques L28
1593384799Blastomere BiopsyUse needle to remove single blastomere during early development to perform genetic analysis - other blastomeres can replicate to replace it L29
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