1 LECTURE: Linkage & Chi-square test Linkage & Chi-squared Test Outline and Objective 2 ? Accounting for disruptions in expected Mendelian ratios ? Application of the Chi-square test ? Objective: At the end of this lesson you should be able to: 1. Define the term linked gene 2. Differentiate between results obtained from linked genes and non-linked genes in dihybrid crosses 3. Write a null hypothesis 4. Apply the chi-squared test to results observed from crosses LECTURE: Linkage & Chi-square test 3 Review ?We have been looking so far at inheritance of genes on different chromosomes. ? Since humans for example, have thousands of traits, each chromosome must carry a large number of genes.