Folate and B12 deficiency Flashcards
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| 4410402840 | What type of anaemia? | Macrocytic | 0 | |
| 4410408559 | Name 6 causes of b12 deficiency | Vegan diet PA GAstrectomy Ileal resection Tropical sprue Crohn's Tapeworm | 1 | |
| 4410416283 | 3 causes of folate deficiency | Poor diet (poverty/alcohol) Increased demand (high cell turnover inflammatory disease) Lactation | 2 | |
| 4410429331 | What does Vitamin B12/cobalamin bind to in the stomach? | IF | 3 | |
| 4410435284 | What secretes intrinsic factor? | Parietal cells | 4 | |
| 4410438602 | Where is the b12 absorbed from? | Terminal ileum | 5 | |
| 4410439481 | Where is folate absorbed? | PRoximal jejunum and duodenum | 6 | |
| 4410444175 | Which tract is often spared in b12 deficiency? | Spinothalamic | 7 | |
| 4410446380 | Name 4 clinical features of b12 deficiency | Lethargy/breathless Bruising/mucosal haemorrhage due to thormbocytopenia Weight loss due to malabsorption Sore mouth (mucosal changes) Peripheral neuropathy (due to myelin degeneration of the posterior/lateral columns of the spinal cord) -> spasticity, impaired sensation of lower limbs etc | 8 | |
| 4410457695 | How would the blood film be for B12 and folate deficiency? | High MCV Oval macrocytes on blood film | 9 | |
| 4410460056 | How would you treat PA? | Injections of b12 (IM/parenteral) | 10 |