Immune System Flashcards

3940549763	innate immunity	is always active against infection but cant target specific pathogens, is nonspecific near entry part of the body macrophage, monocytes, dentric cell, neutrophil release cytokins that trigger an immune response	0
3940555316	adaptive immunity	targets a specific pathogen is slower to act but can maintain memory of pathogen B cells that when activated secrete antibodies that bind to invaders antigen T cells also recognize antigens both have memory divided into humoral (B cells and antibodies) and cell mediated (t cells)	1
3940594890	organs of immnune system	bone marrow: makes WBC spleen: stores blood and activates B cells that turn into plasma cells that turn into antibodies thyums: T cells mature here lymph nodes: where immunue cells are stored and response can be mounted GALT: immune tissue near digestive system tonisils, adenoids, peyers patches in the sm intestine appendix	2
3940629212	lymphatic system		3
3940633522	leukocytes	granolcytes and agranulocytes, both come from hematopoetic stem cells granules are toxic enzymes	4
3940645969	WBC		5
3940651819	hematopoiesis		6
3940716817	non specific cellular defense	skin w/defensins ( enzymes) lysozyme in tears and saliva muscus membranes in resp system GI: gut bacteria and stomach acid complement system : blood proteins interferons: proteins that prevent viral replication and dispersion	7
3940763932	cells of the innate immnune system, Macrophages	macrophages: a granulocyte, dervived from moncytes, phagocytes invader, engulfs it and presents little pieces of it to other cells using MHC which carries an antigen, also release cytokins that stimulate additional immune reponse	8
3940785392	MCH class 1	Major Histocompatibilty complex that carries antigen on a cell surface Class 1: endogeneous pathway of nucleated cells that binds antigens from inside the cell and presents them	9
3940816939	MCH class 2	displayed by professional antigen presenting cells like macrophages, dentritic cells, B cells exergenous pathway, antigens are from the environment	10
3940841537	PRR pattern recognition receptors	macrophages and dentric cells special receptors to recruit the right type of immune cells	11
3940858433	NK cells, innate immune system	non specific lymphocyte that produces apotocisis in virally infected cells , recognizes invaders since do not have MCH1	12
3940880919	granulocytes	neutophilis: most abundant, phagoctyes, can detected bacterica using chemotaxis, are what pus is made of eosinophil: allergic reaction release histamine and cause inflammation basophil: also involved in allergic response mast call: related to basophil	13
3940940133	humoral immunity	involves the production of antibodies produced by B cells	14
3940965182	antibodies or Ig		15
3941004427	cytotoxic immunity postive and negative selection	cell mediated response; T cells postive selection: for T cells that can respond to the specific antigen negative selection: killing cells that self react	16
3941025378	3 types of T cells	helper T cells; CD4 coordinate immune response , these are lost in HIV cytotoxix CD8: directly kill infected cells by injecting them with chemicals that promote aposostis , use MCH1 regulatory or suppressorc CD4:tone down immune response once infection has been fought , prevent autoimmune , MCH2 memory T cells	17
3941078258	self antigen	so self cells are not attacked problem if autoimmune negative selection; thru T cells to kill of these autoimmume cells	18
3941098608	active immunity	immune system stimulated to produce antibodies by exposure ie vaccine	19
3941105299	passive immunity	the transfer of antibodies , ie to fetus	20
3941302056	clonal selection	when only a certain cell with that specifc antibody for the specifc antigen is activated	21