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Iron/B12 deficiency Flashcards

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7795196641Zollinger-Ellison Synromegastric acid inactivates pancreatic proteases which impairs B12 binding to IF0
7795198369Blind loop syndromestasis; colonizing bacteria bind cobalamin Cause of B12 deficiency1
7795200922Diphyllobathrium latum infestationCause of B12 deficiency binds cobalamin and prevents absorption2
7795210323Pancreatic exocrine deficiencyCause of B12 deficiency3
7795255081Pernicious anemiaautoimmune destruction of parietal cells so less IF and less B12 absorption in distal intestine4
7795258523RBC folate testmeasure of folate stores in tissue less sensitive to short-term dietary effects5
7795261382serum folatecheaper6
7795261383increased homocysteine levelsFolate deficiency7
7795263154inadequate dietcause of folate deficiency8
7795271557Hypersegmented neutrophilsB12 deficiency9
7795273962neurological changesB12 deficiency10
7795275595ineffective erythropoiesisdestruction of red cells in marrow can be seen in B12 deficiency retic count is low11
7795279003Megaloblastic anemiaB12 deficiency12
7795281053What does the RBC indicate?anemia13
7795283903Most common cause of anemiairon deficiency anemia14
7795284778reasons for iron deficiency1. diet/malabsorption 2. GI problem/ulcers 3. menstrual bleeding 4. gastric bypass 5. pregnancy (b/c need more iron)15
7795288257CBC in iron deficiencyincreased RDW and platelets decreased MCV, MCH, MCHC, Hgb, Hct, RBC16
7795300388Serum labs in iron deficiencylow serum iron and ferritin increased TIBC17
7795302043Non-megaloblastic anemiaDoes not result from DNA synthesis impairment (EtOH, liver disease) RBC precursors are normal18
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