Vitamin B12 Flashcards
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| 9560362672 | Other name | Cobalamin ; big and many other forms | 0 | |
| 9560367924 | Properties | - High molecular weight, red crystalline - Occurs in complexes with protein in animal food - Increases biological value of protein - Antibiotics increase growth of animals 15-20% by inhibiting growth of microogranicsms that destroy B12 - Contains cobalt; for humans | 1 | |
| 9560415388 | Absorption in stomach | HCl and Intrinsic factor HCL acid splits of B12 from protein complexes in food and salivary protein before denaturing it - elderly may produce less acid Then binds for R factor Splits by proteases and rebinds to Intrinsic Factor | 2 | |
| 9560463602 | Where do most deficiencies come from? | Absoprtion problems, not diet problems | 3 | |
| 9560470483 | Functions | Involved in transfer of methyl groups - removes a methyl to activate folate coenzym THF - Folate donates methyl to activate Vitamin B12 General growth and anemia prevention Protein and fat metabolism DNA formation | 4 | |
| 9560485443 | Deficiencies | -Pernicious anemia (same as macrocytic with folate, but diff name bc B12) - Fatigue and weakness - Irreversible degeneration of nervous system - Can be mistaken for dimentia - High does levels given in brain atrophy - Abnormal blood lipids; coating in tongue | 5 | |
| 9560509481 | Requirements | 2.4 ug ; most diets contain 30-70 ug; most potent | 6 | |
| 9560513643 | Food sources | all animal foods; bioactive supplement | 7 |