Campbell's Biology, 9e (Reece et al.) Chapter 12 The Cell Cycle In this chapter, 24 questions are new, and 12 have been altered to incorporate new material from the textbook. As in the other chapters, any questions that depend on figures or introductory scenarios have been placed at the end of the chapter rather than in concept sequence. Multiple-Choice Questions 1) The centromere is a region in which A) chromatids remain attached to one another until anaphase. B) metaphase chromosomes become aligned at the metaphase plate. C) chromosomes are grouped during telophase. D) the nucleus is located prior to mitosis. E) new spindle microtubules form at either end. Answer: A Topic: Concept 12.1 Skill: Knowledge/Comprehension