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Honors biology chapter 10

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DNA Replication

10.5 DNA Replication proceeds in two directions at many sites simultaneously. Another DNA replication requires the cooperation of more than a dozen enzymes and other proteins. begins at special sites origins of replication Replication bubbles are created when replication proceeds in both directions Thousands of bubbles can be present at once because there are many origins. DNA sugar backbones run in opposite directions. each strand has a three prime end a five prime end. refer to the carbon atoms of the nucleotide strands 5?s: phosphate 3?s: hydroxyl DNA polymerases: link the DNA nucleotides to the growing polymer strand (added only to three prime) can only grow in the five prime/ three prime direction DNA Ligase: links the pieces together into the single DNA strand

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