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Concepts of Genetics Chapter 2 Flashcards

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4694969547chromosomein prokaryotes, a DNA molecule containing the organism's genome; in eukaryotes, a DNA molecule complexed with RNA and proteins to form a threadlike structure containing genetic information arranged in a linear sequence; a structure that is visible during mitosis and meiosis0
4694969548mitosisa form of cell division producing two progeny cells identical genetically to the progenitor cell - that is, the production of two cells from one, each having the same chromosome complement as the parent cell1
4694969549meiosisthe process of cell division in gemetogenesis or sporogenesis during which the diploid number of chromosomes is reduced to the haploid number2
4694969550gamete/sporea specialized reproductive cell with a haploid number of chromosomes3
4694969551chromatinthe complex of DNA, RNA, histones and nonhistone proteins that make up uncoiled chromosomes, characteristic of eukaryotic interphase nucleus4
4694969552eukaryotesorganisms having true nuclei and membraneous organelles and whose cells divide by mitosis and meiosis5
4694969553nucleusthe membrane-bound cytoplasmic organelles of eukaryotic cells that contains the chromosomes and nucleolus6
4694969554nucleolusthe nuclear site of ribosome biosynthesis and assembly; usually associated with or formed in association with the DNA compromising the nucleolar organizer region.7
4694969555nucleolar organizer region (NOR)a chromosomal region containing the genes for rRNA; most often found in physical association with the nucleolus8
4694969556prokaryoteorganisms lacking nuclear membranes and true chromosomes. Bacteria and blue-green algae are examples of these.9
4694969557nucleoidthe DNA-containing region within the cytoplasm in prokaryotic cells10
4694969558endoplasmic reticulum (ER)a membranous organelle system in the cytoplasm of eukaryotic cells. In rough __, the outer surface of the membranes is ribosome-studded; in smooth __, it is not11
4694969559ribosomea ribonucleoprotein organelle consisting of two subunits, each containing RNA and protein molecules. They are the site of translation of mRNA codons into the amino acid sequence of a polypeptide chain12
4694969560mitochondriathe so-called power house of the cell - a self-reproducing, DNA-containing, cytoplasmic organelle in eukaryotes involved in generating the high-energy compound ATP13
4694969561chloroplasta self-replicating cytoplasmic organelle containing chlorophyll and the site of photosynthesis14
4694969562endosymbiont hypothesisthe proposal that self-replicating cellular organelles such as mitochondria and chloroplasts were originally free-living organisms that entered into a symbiotic relationship with nucleated cells15
4694969563centriolea cytoplasmic organelle composed of nine groups of microtubules, generally arranged in triplets. They function in the generation of cilia and flagella and serve as foci for the spindle in cell division16
4694969564centrosomeregion of the cytoplasm containing a pair of centrioles17
4694969565spindle fiberscytoplasmic fibrils formed during cell division that attach to and are involved with separation of chromatids at the anaphase stage of mitosis and meiosis as well as their movement toward opposite poles in the cell.18
4694969566centromerethe specialized heterochromatic chromosomal region at which sister chromatids remain attached after replication and the site to which spindle fibers attach to the chromosome during cell division. Location of these during the anaphase portion of cell division. Also known as the primary constriction19
4694969567diploid (2n)a condition in which each chromosome exists in pairs; having two of each chromosome20
4694969568homologous chromosomeschromosomes that synapse or pair during meiosis and that are identical with respect to their general loci and centromere placement21
4694969569karyotypethe chromosome complement of a cell or an individual. Often used to refer to the arrangement of metaphase chromosomes in a sequence according to length and centromere position22
4694969570haploid (n)a cell or an organism having one member of each pair of homologous chromosomes. Also referred to as the gametic chromosome number23
4694969571genomethe set of hereditary information encoded in the DNA of an organism, including both the protein-coding and non-protein-coding sequences24
4694969572locusthe site or place on a chromosome where a particular gene is located25
4694969573alleleone of the possible alternative forms of a gene, often distinguished from other alleles by phenotypic effects26
4694969574zygotethe diploid cell produced by the fusion of haploid gemetic nuclei27
4694969575karyokinesisthe process of nuclear division28
4694969576cytokinesisthe division or separation of the cytoplasm during mitosis or meiosis29
4694969577cell cyclethe sequence of groth phases of an individual cell; divided into G1, S, G2 and M. A cell may temporarily or permanently be withdrawn from it, in which case it is said to enter the G0 stage30
4694969578interphasein the cell cycle, the interval between divisions31
4694969579G0 phasea nondividing but metabolically active state that cells may enter from the G1 phase of the cell cycle32
4694969580cohesina protein complex that holds sister chromatids together during mitosis and meiosis and facilitates attachments of spindle fibers to kinetochores33
4694969581metaphasethe stage of cell division in which condensed chromosomes lie in a cnetral plane between the two poles of the cell and during which the chromosomes become attached to the spindle fibers34
4694969582kinetochorea fibrous structure with a size of about 400 nm, located within the centromere. It is the site of microtubule attachment during cell division35
4694969583shugoshinsa class of proteins involved in maintaining cohesion of the centromeres of sister chromatids during mitosis and meiosis.36
4694969584anaphasestage of mitosis or meiosis in which chromosomes begin moving to opposite poles of the cell37
4694969585disjunctionthe separation of chromosomes during the anaphase stage of cell division38
4694969586telophasethe stage of cell division in which the daughter chromosomes have reached the opposite poles of the cell and reverse the stages characteristic of prophase, re-forming the nuclear envelopes and uncoiling the chromosomes. Ends with cytokinesis, which divides the cytoplasm and splits the cell in two.39
4694969587cyclinin eukaryotic cells, a class of proteins that are synthesized and degraded in synchrony with the cell cycle and regulate passage through stages of the cycle40
4694969588G1/S checkpointa point in the G1 phase of the cell cycle when a cell becomes committed to initiating DNA synthesis and continuing the cycle or withdraws into the G0 resting stage.41
4694969589crossing overthe exchange of chromosomal material (parts of chromosomal arms between homologous chromosomes by breakage and reunion. The exchange of material between nonsister chromatids during meiosis is the basis of genetic recmobination42
4694969590synapsisthe pairing of homologous chromosomes at meiosis43
4694969591bivalentssynapsed homologous chromosomes in the first phase of meiosis44
4694969592tetradthe four chromatids that make up paired homologs in the prophase of the first meiotic division. In eukaryotes, with a predominant haploid stage (some algae and fungi), a tetrad denotes the four haploid cells produced by a single meiotic division45
4694969593reductional divisionthe chromosome division that halves the number of centromeres and thus reduces the chromosome number by half. The first division of meiosis is an example.46
4694969594dyadthe products of tetrad separation or disjunction at meiotic prophase I. Each one consists of two sister chromatids joined at the centromere47
4694969595equational divisiona division stage where the number of centromeres is not reduced by half but where each chromosome is split into longitudinal halves that are distributed into two daughter cells. Chromosome division in mitosis and the second meiotic division are examples.48
4694969596chaismathe crossed strands of nonsister chromatids seen in diplotene of the first meiotic division. Regarded as the cytological evidence for exchange of chromosomal material, or crossing over49
4694969597nondisjunctiona cell division error in which homologous chromosomes (in meiosis) or the sister chromatids (in mitosis) fail to separate and migrate to opposite poles; responsible for defects such as monosomy and trisomy50
4694969598telophase Ithe stage in the first meiotic division when duplicated chromosomes reach the poles of the dividing cell51
4694970395plasma membranean outer covering that defines the cell boundary and delimits the cell from its immediate external environment52
4694970396cell wallwhat plants have in addition to the plasma membrane that is an outer covering53
4694971459cell coat (glycocalyx)the outer covering that most animal cells have over the plasma membrane54
4694972917receptor moleculesact as recognition sites that transfer specific chemical signals across the cell membrane into the cell55
4694972918cytoplasmthe remainder of the eukaryotic cell within the plasma membrane, excluding the nucleus, that contians a variety of extranuclear cellular organelles56
4694972919cytosola nonparticulate, colloidal material that surrounds and encompasses the cellular organelles57
4694973115microtubuleshelp comprise the cytoskeleton and provides a lattice of support to the cell along side microfilaments58
4694973116tubulina protein that makes up microtubules59
4694973289microfilamentshelp comprise the cytoskeleton and provides a lattice of support to the cell along side microtubules60
4694973290actina protein that makes up microfilaments61
4694974763metacentric62
4694975275submetacentric63
4694975754acrocentric64
4694976122telocentric65
4694976733p armthe shorter arm on the centromere66
4694977141q armthe longer arm on the centromere67
4694982163biparental inheritanceinheritance from two parents68
4694982750sex-determining chromosomeschromosomes that determine sex69
4694984184S phasethe period during which the DNA is synthesized and this period occurs before the cell enters mitosis70
4694984185G1 phase71
4694985076G2 phase72
4694985644sister chromatidsthe two parts of each chromosome73
4695009853prometaphaserefers to the period of chromosome movement74
4695009866kinetochore microtubulesthe microtubules that are most directly responsible for chromosome migration, and make contact with and adhere to kinetochores75
4695010172daughter chromosomeduring anaphase, the migrating chromatids are called _______________________76
4695010346molecular motors77
4695011564cell plate78
4695011565middle lamellathe cell plate laid down during telophase becomes a structure called the _________________________79
4695011566cell furrow80
4695012246cell division cycle (cdc) mutations81
4695012247kinasesthe normal products of many of the mutated genes are enzymes called _________________82
4695012784G2/M checkpointthe checkpoint where DNA is monitored prior to the start of mitosis83
4695013787M checkpointthe successful formation of the spindle fiber system and then attachment of spindle fibers to the kinetochores associated with the centromeres are monitored at this checkpoint84
4695013911monads85
4695013912prophase I86
4695014330leptotene stagethe interphase chromatin material begins to condense and the chromosomes become visable87
4695014331chromomereslocalized condensations on a chromosome that resemble beads on a string88
4695014451homology search89
4695014452zygotene stagechromosomes continue to shorten and thicken during this stage90
4695015507synaptonemal complexa more extensive ultrastructurual component begins to form between the homologs91
4695015508pachytene stagethe chromosomes continue to coil and shorten, and further developement of the synaptonemal complex occurs between the two members of each bivalent at this stage92
4695015795diplotene stageeach tetrad consists of two pairs of sister chromatids at this stage93
4695016188diakinesisthe final stage of prophase I where the chromosomes pull farther apart but nonsister chromatids remain loosly associated at the chiasmata94
4695016189terminalizationas separation proceeds in diakinesis, the chiamata move toward the ends of the tetrad95
4695016352metaphase I96
4695016637anaphase Ithe stage in the first meiotic division during which members of homologous pairs of chromosomes separate from one another.97
4695017914meiosis II98
4695019455prophase II99
4695019608metaphase II100
4695020074anaphase II101
4695020375telophase II102
4695020761spermatogenesis103
4695020762spermatogoniumundifferentiated diploid germ cell104
4695021079primary spermatocytethe germ cell that undergoes the first meiotic division105
4695021080secondary spermatocytesthe product of the first meiotic division106
4695021229spermatidsthe two haploid cells that are produced from meiosis II107
4695021402spermiogenesisthe series of developmental changes that the spermatids go through in order to become highly specialized108
4695022444spermatozoa (sperm)highly specialized cells109
4695022445oogenesis110
4695022446ovaeggs111
4695022774primary oocyte112
4695022775oogonium113
4695022891first polar bodythe dyads at one pole are pinched off with very little surrounding cytoplasm to form the ______________________114
4695022892secondary oocyte115
4695022893ootid116
4695023028secondary polar body117
4695023176sporophyte stage118
4695023177gametophyte stage119
4695026131folded-fiber model120

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