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16- AP Biology Campbell Chapter 16 - Molecular Basis of Inheritance Flashcards

Campbell AP Biology Chapter 16 9th edition vocabulary

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3593149451BacteriaOne of two prokaryotic domains, the other being Archaea.0
3593149452BacteriophageA virus that infects bacteria; also called a phage.1
3593149453BacteriumMember of the prokaryotic domain Bacteria.2
3593149454ChromatinThe complex of DNA and proteins that makes up a eukaryotic chromosome. When the cell is not dividing, chromatin exists in its dispersed form, as a mass of very long, thin fibers that are not visible with a light microscope.3
3593149455deoxyriboseThe sugar component of DNA nucleotides, having one fewer hydroxyl group than ribose, the sugar component of RNA nucleotides.4
3593149456DNA ligaseA linking enzyme essential for DNA replication; catalyzes the covalent bonding of the 3' end of one DNA fragment (such as an Okazaki fragment) to the 5' end of another DNA fragment (such as a growing DNA chain).5
3593149457DNA polymeraseAn enzyme that catalyzes the elongation of new DNA (for example, at a replication fork) by the addition of nucleotides to the 3' end of an existing chain. There are several different DNA polymerases; DNA polymerase III and DNA polymerase I play major roles in DNA replication in prokaryotes.6
3593149458Double helixThe form of native DNA, referring to its two adjacent antiparallel polynucleotide strands wound around an imaginary axis into a spiral shape.7
3593149459EuchromatinThe less condensed form of eukaryotic chromatin that is available for transcription.8
3593149460HelicaseAn enzyme that untwists the double helix of DNA at the replication forks, separating the two strands and making them available as template strands.9
3593149461HeterochromatinEukaryotic chromatin that remains highly compacted during interphase and is generally not transcribed.10
3593149462HistoneA small protein with a high proportion of positively charged amino acids that binds to the negatively charged DNA and plays a key role in chromatin structure.11
3593149463Lagging strandA discontinuously synthesized DNA strand that elongates by means of Okazaki fragments, each synthesized in a 5'3' direction away from the replication fork.12
3593149464Leading strandThe new complementary DNA strand synthesized continuously along the template strand toward the replication fork in the mandatory 5'?3' direction.13
3593149465Mismatch repairThe cellular process that uses specific enzymes to remove and replace incorrectly paired nucleotides.14
3593149466NucleaseAn enzyme that cuts DNA or RNA, either removing one or a few bases or hydrolyzing the DNA or RNA completely into its component nucleotides.15
3593149467NucleoidA dense region of DNA in a prokaryotic cell.16
3593149468Nucleoid regionA dense region of DNA in a prokaryotic cell.17
3593149469NucleosomeThe basic, bead-like unit of DNA packing in eukaryotes, consisting of a segment of DNA wound around a protein core composed of two copies of each of four types of histone.18
3593149470Nucleotide excision repairA repair system that removes and then correctly replaces a damaged segment of DNA using the undamaged strand as a guide.19
3593149471Okazaki fragmentA short segment of DNA synthesized away from the replication fork on a template strand during DNA replication, many of which are joined together to make up the lagging strand of newly synthesized DNA.20
3593149472Origin of ReplicationSite where the replication of a DNA molecule begins, consisting of a specific sequence of nucleotides.21
3593149473PhageA virus that infects bacteria; also called a bacteriophage.22
3593149474PrimaseAn enzyme that joins RNA nucleotides to make the primer using the parental DNA strand as a template.23
3593149475PrimerA short stretch of RNA with a free 3' end, bound by complementary base pairing to the template strand, that is elongated with DNA nucleotides during DNA replication.24
3593149476PyrimidineOne of two types of nitrogenous bases found in nucleotides, characterized by a six-membered ring. Cytosine (C), thymine (T), and uracil (U) are pyrimidines.25
3593149477Radioactive isotopeAn isotope (an atomic form of a chemical element) that is unstable; the nucleus decays spontaneously, giving off detectable particles and energy.26
3593149478Repetitive DNANucleotide sequences, usually noncoding, that are present in many copies in a eukaryotic genome. The repeated units may be short and arranged tandemly (in series) or long and dispersed in the genome, called repeats.27
3593149479Replication forkA Y-shaped region on a replicating DNA molecule where the parental strands are being unwound and new strands are being synthesized.28
3593149480Semiconservative modelType of DNA replication in which the replicated double helix consists of one old strand, derived from the old molecule, and one newly made strand.29
3593149481Single-strand DNA-binding proteinA protein that binds to the unpaired DNA strands during DNA replication, stabilizing them and holding them apart while they serve as templates for the synthesis of complementary strands of DNA.30
3593149482TelomeraseAn enzyme that catalyzes the lengthening of telomeres in eukaryotic germ cells.31
3593149483TelomereThe tandemly repetitive DNA at the end of a eukaryotic chromosome's DNA molecule that protects the organism's genes from being eroded during successive rounds of replication. See also repetitive DNA.32
3593149484Template strandThe DNA strand that provides the pattern, or template, for ordering, by complementary base pairing, the sequence of nucleotides in an RNA transcript.33
3593149485TopoisomeraseA protein that breaks, swivels, and rejoins DNA strands. During DNA replication, topoisomerase helps to relieve strain in the double helix ahead of the replication fork.34
3593149486Transformation(1) The conversion of a normal animal cell to a cancerous cell. (2) A change in genotype and phenotype due to the assimilation of external DNA by a cell. When the external DNA is from a member of a different species, transformation results in horizontal gene transfer.35
3593149487X-ray crystallographyA technique used to study the three-dimensional structure of molecules. It depends on the diffraction of an X-ray beam by the individual atoms of a crystallized molecule.36
3593149488antiparallelReferring to the arrangement of the sugar-phosphate backbones in a DNA double helix (they run in opposite 5' ---> 3' directions.)37
3593149489virusAn infectious particle incapable of replicating outside of a cell, consisting of an RNA or DNA genome surrounded by a protein coat (capsid) and, for some viruses, a membranous envelope.38

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