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7885333911Skeletal Cartilage-Made of some variety of cartilage tissue molded to fit its body location and function -Surrounded By a layer of dense irregular connective tissue -contains no nerves or blood vessels - ability to spring back after compressed -mainly water0
7885333912perichondrium-Dense irregular connective tissue membrane covering cartilage -Acts like a girdle to resist out word expansion when Cartilage is compressed - contains blood vessels from which nutrients diffuse through the matrix to reach cells internally1
7885333913types of cartilagehyaline, elastic, fibrocartilage2
7885333914components of Cartilage-Cells are chondrocytes -Lacunae- cells are encased in small cavities -All are in a extra cellular matrix -Matrix contains jelly like substance and fibers -Has a flexible matrix that can accommodate mitosis3
7885333915Growth of cartilageAppositional growth and interstitial growth4
7885333916Bone functionsSupport provide framework, protection, Anchorage, mineral and growth factor storage, blood cell formation, hormone production, triglyceride storage (fat)5
7885333917Bone classification-Axial skeleton(skull vertebrae column and rib cage), -appendicular( upper and lower limbs and girdles) -Long bones has a shaft and two ends - short bones cube shaped - flat bone or thin,flattened, bit curved - irregular bone complicated shapes6
7885333918spongy bonesInternal layer, is porous highly vascular, in his inner portion made of trabeculae Makes bone lighter and provide space for bone marrow7
7885333919compact bonesExternal layer, covered by periosteum, serves for attachment of muscles, provides protection and gives durable strength8
7885333920Cells of bone tissueOsteocytes, osteogenic, osteoblast, osteoclast9
7885333921Osteocytes areMature bone cells10
7885333922osteogenic cellsstem cells11
7885333923OsteoblastsBone building cells12
7885333924OsteoclastsBone resorbing cell13
7885333925OsteonsStructural unit of compact bone Elongated cylinder parallel to the long axis of bone14
7885333926LamellaMatrix tube Concentric layers where organic matrix is deposited Collagen fibers in bone salts Surround a common center called the Haversian Canal15
7885333927Volkmann's canalsconnect Haversian canals How blood gets inside bone16
7885333928LacunaeSmall cavities in the bone or cartilage that hold individual bones or cartilage cells.17
7885333929CanaliculiHairlike canals that connect lacunae to each other and the central canal18
7885333930interstitial lamellaeAreas between the Haversian systems arranged irregularly19
7885333931organic components of bonebone cells and osteoid20
7885333932OsteoidMakes up 1/3 of the matrix unmineralized bone matrix composed of proteoglycans, glycoproteins, and collagen21
7885333933inorganic components65% of mass,mineral salts Largely calcium phosphate22
7885333934OssificationProcess of bone formation Embryo eight weeks until born the process is for bony skeleton Later called bone growth until adulthood23
7885333935intermembranous ossification-bone development within a membrane -how skull bones develop At eight weeks of development begins with in fibrous CT membranes formed by mesenchymal cells24
7885333936endochondral ossificationAll bones below the skull 90% except for clavicles are formed process in which bone forms by replacing hyaline cartilage Begins at the primary ossification center25
7885333937Steps of endochondral ossificationUnderlying mesenchymal cells specialize in to osteoblast 1. A bone color forms around the diaphysis 2. Cartlidge in the center of diaphysis calcifies and develops cavities 3. The periosteum bud invades The internal cavities and spongy bone forms 4. The diaphysis elongates and a medullary cavity forms 5. The epiphyses ossify26
7885333938Steps of intramembranous ossification1. Ossification centers appear in the fibrous connective tissue membrane 2. Osteoid is secreted with in the fibrous membrane and calcifies 3. Woven bone and periosteum form 4. Lamellar bone replaces woven bone, just deep into the periosteum, Red marrow appears27
7885333939Growth in length of long boneGrowth in length of long bone occurs at the epiphyseal plate Proliferation zone- Cartlidge cells undergo mitosis Hypertrophic zone- older Cartlidge cells enlarge Calcification zone- Matrix calcifies, cartilage cells die, matrix begins degenerating blood vessels invade cavity Ossification zone- New bone forms28
7885333940epiphyseal plate closureoccurs when epiphysis and diaphysis fuse29
7885333941DiaphysisThe shaft of a long bone30
7885333942medullary cavityCavity lined with a thin layer of connective tissue you called Endosleum and contains yellow bone marrow31
7885333943EpiphysisEnd of a long bone32
7885333944red bone marrowhemopoietic tissue, within the trabecular cavities33
7885333945nutrient foramina"openings"; nerve fibers and blood vessels supply the periosteum through these openings34
7885333946epiphyseal plateIs between the diaphysis and epiphanies where mitotic activity takes place35
7885333947epiphyseal lineReplaces the plate when bone growth is complete36
7885333948PeriosteumDense white fibrous tissue covering bone, highly vascular layer, a place for tendon muscle attachment37
7885333949interstitial growthDuring infancy and young long bones Lincoln of the epiphyseal plate Cartilage and it's replacement38
7885333950appositional growthincrease in bone thickness39
7885333951non displaced fracturebone ends retain their normal position40
7885333952displaced fractureA fracture in which bone fragments are separated from one another and not in anatomic alignment.41
7885333953complete fracturebone is broken all the way through42
7885333954incomplete fracturebone is not broken all the way through43
7885333955compound fracturebone breaks through the skin44
7885333956simple fracturebone is broken cleanly; the ends do not penetrate the skin45
7885333957fracture treatment1. A hematoma forms 2. Fibrocartilaginous callus forms 3. Bony callus forms 4. Bone remodeling occurs46
7885333958HematomaClot forms at fracture, bone cells die, become swollen painful inflamed47
7885333959fibrocartilaginous callus"Soft callus" capillaries grow into the hematoma and phagocytic cells begin cleanup, fibroblast and osteoblast begin rebuild48
7885333960bony callusa callus made of spongy bone49
7885333961bone remodelingRemodeling a spongy bone and compact bone50
7885333962joint structureMaterial binding the bones together and whether or not a joint cavity is present51
7885333963Types of structural jointsFibrous, cartilaginous, synovial52
7914323128Synovial joints have a joint cavityTrue53
7914323129Function of jointBased on the amount of movement allowed at the joint54
7914323130Three types of joint functionSynarthrotic, amphiarthrotic, diarthrotic55
7914323131Synarthroticimmovable joint56
7914323132AmphiarthroticSlightly movable57
7914323133DiarthroticFreely movable58
7914323134fibrous jointsHas NO joint cavity consists of inflexible layers of dense connective tissue, holds the bones tightly together59
7914323135Three types of fibrous jointSutures, Syndesmosis, Gomphoses,60
7914323136Sutures"Sewing together" very stable because the opposing Bones have interlocking61
7914323137SyndesmosisBones connected by ligaments Varies between synarthrotic and amphiarthrotic distal attachment of tibia and fibula62
7914323138GomphosisA bolting together binds the teeth into the jaw synarthrotic63
7914323139cartilaginous jointsHave NO joint cavity allow only slight movement and consist of bones connected entirely by cartilage (ribs to sternum)64
7914323140Two types of cartilaginous jointssynchondroses and symphyses65
7914323141Synchondrosis-bones are bound by hyaline cartilage Found at the epiphyseal plate -Ex. rib attachment to sternum by costal cartilage Synarthrotic66
7914323142symphysisgrowing together (as in symphysis pubis) Separated by a wedge or pad of fibrocartilage intervertebral dics Amphiarthrotic67
7914323143synovial jointsContain a joint cavity Diarthrosis are freely movable joints the bones are separated by a fluid. The fluid is called synovial fluid. Most of the bodies joints all of the limbs.68
7914323144All synovial joints are diarthrosis and all diarthrosis are synovial jointsTrue69
7914323145Characteristics of synovial jointHas a articular Cartlidge (absorption) Has a joint cavity Articular Cartlidge is the hyline Cartlidge of a joint70
7914323146Synovial Joint capsuleis composed of dense irregular connective tissue on the tough external fibrous layer. On the inner layer of capsule is synovial membrane that is composed of loose connective tissue71
7914323147Types of synovial jointTemporomandibular, shoulder, hip, knee72
7914323148temporomandibular joint (TMJ)Luxtion dislocated Subluxation partial dislocated73
7914323149Shoulder Joints"Ball socket" stability is compromised, 1/3 the size of a humeral head. Glenoid labrum secures the head of the humerus against the glenoid cavity ligaments are coracohumeral, glenohumeral, four tendons (rotator cuff)74
7914323150hip jointball and socket Stability is not compromised. The head of the femur is smaller than the acetabular fossa after the labrum is added the head is fit snugly to where it is rare for the head to come out. The ligament/tendon's keep the head "screwed in".75
7914323151Knee JointsMost complex, one joint cavity, has three joints in one. Common knee injuries are known as the three C's. Collateral ligament's, cruciate, and Cartlidges . Cartlidge is vascular so healing will not happen76
7914323152ArthritisIs the most widespread crippling disease in the US. Over 100 types of inflammatory or degenerative disease that damages the joint77
7914323153Forms of arthritisAcute and chronic78
7914323154acute arthritiswhat kind of arthritis usually results from bacterial invasion?79
7914323155chronic arthritisLong term80
7914323156Two main types of arthritisOsteoarthritis and rheumatoid81
7914323157OsteoarthritisDegenerative joint disease82
7914323158rhematoid arthritisInflammatory autoimmune disease where the synovial membrane becomes inflammated83
7914323159Osteophytes are:bony spurs84
7914323160CrepitusA crackling sound most often used to refer to bones rubbing against one another.85
7914323161Four categories of tissueEpithelial tissue Connective tissue Nervous tissue Muscular tissue86
7914323162Characteristics of muscleExcitability, contractility, extensibility, elasticity87
7914323163Muscle ExcitabilityAbility of a cell to receive and respond to a stimulus88
7914323164ContractilityAbility to shorten and thicken89
7914323165ExtensibilityAbility to extend or stretch90
7914323166Elasticityability to recoil to resting length Ie return to original shape91
7914323167Functions of muscleMotion, maintain posture, stabilize and strengthen joints, protection, heat production92
7914323168Three types of muscle tissueSkeletal, cardiac, smooth93
7914323169skeletal musclesstriated and voluntary94
7914323170cardiac muscleOnly in the heart, striated, involuntary95
7914323171smooth musclevisceral, nonstriated, involuntary96
7914323172fasciaa band or sheet of fibrous connective tissue that covers, supports, and separates muscle97
7914323173Types of Fascia (CT)Epimysium, perimysium, endomysium98
7914323174Epimysium"Outside the muscle" surrounds all the Fascicles muscle bundles99
7914323175Perimysium"Around" covering on the fascicles( bundles) each one100
7914323176Endomysium"Within" surrounds each muscle fiber cell their functions keep muscles from over stretching, carries blood vessels and nerves101
7914323177TendonsAttach muscle to bone102
7914323178AponeurosesSheet-like structure flattened103
7914323179Epimysiumsurrounds entire muscle104
7914323180fascicles areis a collection of muscle bundles to make up the muscle which are surrounded by Perimysium105
7914323181Five types of architecture of muscle fasciclesParallel, fusiform, convergent, pennate, circular106
7914323182muscle cellIs a collection of fibers to make up the fascicles they are surrounded by the endomysium107
7914323183Skeletal muscle cellCylindrical, multi-nucleated, long108
7914323184SarcolemmaPlasma membrane of a muscle cell109
7914323185SarcoplasmCytoplasm of a muscle cell110
7914323186MyofibrilsMake up the muscle fiber cell contains myofilaments protein plus actin111
7914323187Myofilaments areProtein plus acting or myosin112
7914323188actin filamentsthin filaments F-actin, troponin, and tropomyosin113
7914323189MyosinThick filament Protein, rod like with heads114
7914323190sarcoplasmic reticulumIs smooth endoplasmic reticulum interconnecting tubules surrounded each myofibril releases calcium for contraction115
7914323191Calcium is high outside the cell, low inside the cell, high in the Sarcoplasmic reticulum, and high in the T tubulesTrue116
7914323192terminal cisternaePerpendicular cross channels117
7914323193T- tubulesInfolding of sarcolemma they wrap around and connect all myofibrils allow nerve impulses to travel deep into the cell118
7914323194triad relationshipTerminal cisternae, T-tubule, terminal cisternae the terminal cisternae sits on both sides of the T-tubules119
7914323195MyofilamentsActin and myosin organized into highly ordered units called sarcomeres120
7914323196SarcomeresSmallest contractile unit of a muscle fiber. Is the area between 2 Zdisc121
7914323197Z discConsist of actin myosin and elastin122
7914323198I bandIs the area of thin filament only a part of two sarcomere I band overlaps the A band123
7914323199A bandThe entire thick filament. A band does not overlap I band124
7914323200H zoneThick filament only125
7914323201myosin cross bridgeCalcium will bind to the complex to change the shape, myosin can now bind, the attachment of the myosin is called a cross bridge126
7914323202Myosin 2 formsHigh energy Myosin head is cocked back Low energy when attached to binding site At rest the myosin head is at high energy you need ATP for both contraction and releasing.127
7914323203myosin headsStores ATP (few seconds)128
7914323204creatinine phosphateStorage molecule of ATP 10 sec129
7914323205Max muscle powerMyosin and creatinine provide about 14- 16 seconds of Max muscle power130
7914323206AnaerobicGlycolysis splitting of glucose Yields 2 ATP131
7914323207Aerobic( rest and light to moderate exercise 95% of ATP) yields 36 ATP132

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