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AP Biology Metabolism Flashcards

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5000604576Metabolismthe totality of an organisms chemical reactions that result from interactions between molecules within the cell0
5000604577metabolic pathwaya sequence of chemical reactions undergone by a compound in a living organism, start with substrate end with product1
5000604578catabolic pathwaybreaking a complex molecule down into its simpler parts, releasing energy. ie. cellular respiration2
5000604579anabolic pathwayusing energy to build complex molecules from simpler molecules. ie. protein synthesis3
5000604580Bioenergeticsthe study of how organisms manage their energy resources4
5000604581energycapacity to cause change, do work5
5000604582kinetic energyenergy of motion6
5000604583heat(thermal energy)kinetic energy associated with random movement of molecules7
5000604584potential energyenergy of position8
5000604585chemical energypotential energy available for release in a chemical reaction, energy within bonds9
5000604586thermodynamicsstudy of energy transformations10
5000604587closed systemisolated from surroundings, no energy transfer, cant work at equilibrium bc its exhausted its ability to do work. free energy at a min11
5000604588open systemnot isolated, energy and matter can be transferred between system and surroundings, ie. cells12
50006045891st law of thermodynamicsenergy of the universe is constant, cannot be created or destroyed, can only be transferred or transformed, conservation of energy13
50006045902nd law of thermodynamicsduring every energy transfer, some energy is unusable and often lost, every energy transfer or transformation increases the total entropy of the universe14
5000604591entropydisorder, randomness15
5000604592free energydelta G, energy that can do work when temperature and pressure are constant, related to change in enthalpy(delta H), change in entropy(delta S) and temperature in Kelvin(T). delta G = delta H - T delta S16
5000604593exergonic reactiona reaction with a net release of free energy, negative free energy, spontaneous17
5000604594endergonic reactiona reaction that absorbs free energy from its surroundings, non-spontaneous, positive free energy18
5000604595coupled reactionsthe use of exergonic processes to drive endergonic ones, the energy given off from the exergonic is absorbed by the endergonic19
5000604596ATPadenosine triphosphate, composed of ribose (5 carbon sugar), adenine (nitrogenous base), and 3 phosphate groups. Phosphate tail can be broken through hydrolysis to produce energy, ADP, and an inorganic phosphate20
5000604597phosphorylationhow ATP drives endergonic reactions, covalently bonding a phosphate with another molecule, such as as reactant21
5000604598catalysta chemical agent that speeds up chemical reactions without being consumed by the reaction22
5000604599enzymesa catalytic protein, speeds up metabolic reactions by lowering activation energy, very specific, reusable, unchanged by reaction23
5000604600activation energyinitial energy needed to start a chemical reaction, free energy for activating reaction, given off by heat24
5000604604induced fitbrings the chemical groups of the active site into positions that enhance their ability to catalyze the reaction, makes the enzyme more effective25
5000604611cooperativityanother type of allosteric activation, binds to one active site but locks ALL active sites open, allowing products to be constantly produced26
5022149116Substratethe REACTANT that an enzyme acts on27
5022156194Enzyme-Substrate Complexenzyme and substrate28
5022158916Active Siteregion on the enzyme where substrate binds29
5022165190Hydrogen and Ionic Bondssubstrate held in active site by WEAK interactions30
5022183255Lock and Keyactive site on enzyme fits substrate exactly31
5022373242If reaction doesnt need energy to start (exergonic)How do you know if a reaction is spontaneous?32
50224193613 kinds of cellular work done by ATPShuttle renewable and nonrenewable ENERGY, provide ENERGY for cellular functions, provide ENERGY for catabolic reactions33
5022694913Ways enzymes lower activation energycan do this by having a favorable environment, straining substrate molecules, orienting substrates correctly34
5022700044hydrolysishappens when phosphate leaves ATP to give energy to something else. This causes ATP to become ADP, produces water35
5033909425cofactorsnon-protein enzyme helpers ex. zinc, iron, copper36
5033912773coenzymesorganic enzyme helpers ex. vitamens37
5033918798Denatureabove a certain temp activity declines, protein unwinds38
5033921867Renaturecoils it back to normal after temp gets too high and the activity decreased39
5033931702Gene Regulationcell switches on or off the genes that code for specific enzymes40
5033934849Feedback inhibitionend product of a pathway that continues to produce product (positive) and then turns off (negative)41
5033965692negative feedback inhibitionaccumulation of end product slows the process that produces that amount -stop production42
5033972126positive feedback inhibitionend product speeds up production (less common)43
5033994410Allosteric Regulationcan accelerate or inhibit production and enzyme activity by attaching to another part of the protein. this changes the shape of the active site which inhibits substrates from bonding and producing more products44
5034127294Activatorone of the allosteric regulators, stabilizes and keeps active site open for production, wedges open45
5034133569Inhiibitorone of the allosteric regulators, doesnt allow active site to work or produce, wedges closed46
5034141098Competitive Inhibitorinhibitor that mimics original substrate by blocking the original substrate47
5034147169Noncompetetitive Inhibitorbind to another part of enzyme to change shape and block substrate from producing48
5034566267ways enzymes are affectsenvironment, pH, temp, salinity, chemicals that infuse enzyme, increase activity by increasing substrate concentration49
5037143968exergonicwhat reaction is spontaneous (-G)50
5037150506endergonicwhat reaction is not spontaneous (positive G)51

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