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AP Biology: Genetics Flashcards

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6491906450AllelesThe different forms of a gene. Y and y are different alleles of the gene that determines seed color. Alleles occupy the same locus, or position, on chromosomes.0
6491906451AutosomalA locus on any chromosome but a sex chromosome. Not sex-linked.1
6491906452co-dominant allelesTwo different alleles at a locus are responsible for different phenotypes, and both alleles affect the phenotype of the heterozygote. For example, consider blood type in which an individual who inherits both A and B alleles will express both proteins on the blood cell's surface.2
6491906453complete linkageComplete linkage describes the inheritance patterns for 2 genes on the same chromosome when the observed frequency for crossover between the loci is zero.3
6491906454dominant traitA trait expressed over another trait.4
6491906455Drosophila melanogasterThe fruit fly, a favorite organism for genetic analysis.5
6491906456EpistasisOne gene masks the expression of a different gene for a given trait. Ex: fur color in labrador retreivers6
6491906457F1 generationFirst filial; Offspring of a cross between two parents for a trait of interest7
6491906458F2 generationSecond filial;Offspring of a cross involving the F1 generation.8
6491906459GenotypeThe genes inherited for a given trait. For a single trait on an autosome, an individual can be homozygous for the dominant trait, heterozygous, or homozygous for the recessive trait.9
6491906460HeterozygousDiffering alleles for a trait in an individual, such as Yy.10
6491906461homologous chromosomesThe pair of chromosomes in a diploid individual that have the same overall genetic content.11
6491906462HomozygousBoth alleles for a trait are the same in an individual. They can be homozygous dominant (YY), or homozygous recessive (yy).12
6491906463Hybridheterozygous; usually referring to the offspring of two true-breeding (homozygous) individuals differing in the traits of interest.13
6491906464incomplete dominanceIntermediate phenotype in F1, parental phenotypes reappear in F2. The flowers of the snapdragon plant can be red, pink, or white. Color is determined at a single locus. The genotype RR results in red flowers and rr results in white flowers. The heterozygote genotype of Rr results in pink flowers. When the heterozygote has a different, intermediate phenotype compared to the homozygous dominant or homozygous recessive individuals.14
6491906465lethal allelesMutated genes that are capable of causing death.15
6491906466Linkagegenes that are inherited together on the same chromosome. Three inheritance patterns are possible: non-linkage (independent assortment), Partial linkage, and complete linkage.16
6491906467mendel's law of independent assortment of allelesAlleles of different genes are assorted independently of one another during the formation of gametes.17
6491906468mendel's law of segregationAlleles segregate from one another during the formation of gametes.18
6491906469monohybrid crossCross involving parents differing in only one trait.19
6491906470MutationChange in the DNA sequence of a gene to some new, heritable form. Generally, but now always a recessive allele.20
6491906472partial linkagePartial linkage describes one of the inheritance patterns for 2 genes on the same chromosome, when the expected frequency for crossover between the loci is greater than zero but less than one. From partial linkage analysis we can learn about the order and spacing of genes on the same chromosome.21
6491906473PhenotypeThe physical appearance of an organism with respect to a trait, i.e. yellow (Y) or green (y) seeds in garden peas. The dominant trait is normally represented with a capital letter, and the recessive trait with the same lower case letter.22
6491906474PleiotropicA single gene determines more than one phenotype for an organism. ex: coloration of siamese cat and cross eyes23
6491906475recessive traitThe opposite of dominant. A trait that is masked when the dominant allele is present.24
6491906476sex chromosomesSex determination is based on sex chromosomes; X chromosome does contain additional genes25
6491906477sex-linkedA gene coded on a sex chromosome, such as the X-chromosome linked genes of flies and man.26
6491906479true-breedingHomozygous for the true-breeding trait.27
6491906480wild-type alleleThe non-mutant form of a gene, encoding the normal genetic function. Generally, but not always a dominant allele.28
6491906481Principles of DominanceIn the heterozygous individual the dominant trait will be expressed29
6491906482incomplete dominancea condition in which a trait in an individual is intermediate between the phenotype of the individual's two parents because the dominant allele is unable to express itself fully30
6491906483hybridoffspring of crosses between parents with different traits31
6491906484homozygoushaving identical alleles at corresponding chromosomal loci32
6491906485heterozygoushaving dissimilar alleles at corresponding chromosomal loci33
6491906486Punnett squarea chart that shows all the possible combinations of alleles that can result from a genetic cross34
6491906487test crossthe crossing of an individual of unknown genotype with a homozygous recessive individual to determine the unknown genotype35
6491906488dihybrid crossA cross between two individuals, concentrating on two definable traits36
6491906489pedigreea diagram that shows the occurrence of a genetic trait in several generations of a family37
6491906490mutationsRandom errors in gene replication that lead to a change in the sequence of nucleotides; the source of all genetic diversity38
6491906491multiple allelesthree or more forms of a gene that code for a single trait; ex: ABO blood group39
6491906492codominanceinheritance pattern in which a heterozygote expresses the distinct traits of both alleles40
6491906493penetranceThe percentage of individuals with a particular genotype that actually displays the phenotype associated with the genotype.41
6491906494expressivitythe degree to which a genotype is expressed in an individual42
6491906495genetic linkagetendency for alleles of genes on the same chromosome to be inherited together43
6491906496recombination frequencypercentage of recombinants, meaning percentage of of offspring that had traits from crossover. recombination frequencies are lower when alleles are closer together.44
6491906497map unitsA measurement of the distance between genes; one map unit is equivalent to a 1 percent recombination frequency.45
6491906498sex-linked inheritanceAn inheritance pattern whereby genes carried on the sex chromosomes (the X and the Y) are more likely to be expressed in males because they only have one X chromosome.46
6491906500SRY genea gene, located on the Y chromosome, that functions as a master switch, committing the sex of a developing embryo to "male."47
6491906502carrierindividual who has one copy of the allele for a recessive disorder and does not exhibit symptoms48
6492054646KaryotypeRepresentation of the number and visual appearance of the chromosomes in the cell nuclei of an organism or species; will show chromosomal disorders such as Down syndrome49
6492192566Polygenic traitsPhysical traits that are the result of multiple genes being expressed; ex: skin color, hair color50
6492213756Gregor MendelThe father of genetics; studied pea plants and established the particle theory of inheritance as well as law of segregation and independent assortment51
6492228616Thomas Hunt MorganStudied fruit flies and determined that genes can be linked on the same chromosome52
6492246875Environmental influenceEnvironmental conditions can influence phenotype; temperature, light and pH can help determine appearance53
6492272371mutationa change in DNA54
6492275331Chromosome mutationA mutation in which a portion of chromosome is lost or added; ex: translocation55
6492284068Gene mutationA mutation in which a given gene is changed; ex: substitution, insertion or deletion of nucleotide56
6492311734Chi squarea statistical method assessing the goodness of fit between observed values and those expected theoretically; used in genetics to compare offspring data to those projected by Punnett squares57

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