8155592007 | What's the MOA of *progestins* as contraceptives? | 1. *Thicken cervical mucus* 2. Endometrial atrophy 3. Block LH surge (inhibit ovulation) | 0 | |
8155592008 | What'a really effective way to *suppress ovulation*? | IM Medroxyprogesterone | 1 | |
8155592009 | What are the *progestin* drugs, again? | Norethinrone + ones with *-gest* | 2 | |
8155592010 | What's the MOA of *estrogens* as contraceptives? | Suppression of FSH release form pituitary (assists in preventing LH surge & ovulation) | 3 | |
8155592011 | *Ethinyl estradiol* is a(n) _____________. | Synthetic estrogen | 4 | |
8155592012 | *Mestranol * is a(n) _____________. | Synthetic estrogen | 5 | |
8155592013 | *Estradiol valerate* is a(n) _____________. | Synthetic estrogen | 6 | |
8155592014 | *Norethindrone* is a(n) _____________. | Progestin | 7 | |
8155592015 | *Norgestrel* is a(n) _____________. | Progestin | 8 | |
8155592016 | *Levonorgestrel * is a(n) _____________. | Progestin | 9 | |
8155592017 | *Drospirenone * is a(n) _____________. | Progestin (Mineralocorticoid blocker, like spironolactone) | 10 | |
8155592018 | *Norelgestromin* is a(n) _____________. | Progestin | 11 | |
8155592019 | *Etonogestrel* is a(n) _____________. | Progestin | 12 | |
8155592020 | What *progestin* is given as an *IM injection*? | Medroxyprogesterone | 13 | |
8155592021 | What *progestin* is a *testosterone derivative*? | Norethindrone (*Drone* for testoster*one*) | 14 | |
8155592022 | Which *progestin* is given as an *implant*? | Norgestrel | 15 | |
8155592023 | What *progestin* is given as an *IUD*? | Levonorgestrel (*Levo-*tates within the uterus) | 16 | |
8155592024 | What *progestin* is given as a *patch*? | Norelgestromin (Stroma is like skin, patch goes on the skin) | 17 | |
8155592025 | What *progestin* is given as a *vaginal ring* OR as an *implant*? | Etonogestrel (Et tu... globe theatre... circle... ring... yea) | 18 | |
8155592026 | Which ones lasts longer— *Medroxyprogesterone or Etonogestrel*? | Etonogestrel. It lasts 3 years. Medroxyprogesterone lasts 3 mos. | 19 | |
8155592027 | How is *norethindrone* given? | Orally | 20 | |
8155592028 | A BC pill has a *fixed amount* of estrogen and progestin taken for 21 days. What kind of regimen in this? | Monophasic | 21 | |
8155592029 | A BC pill has a *2-3 different pills with varying amount* of estrogen and progestin taken for 21 days. What kind of regimen in this? | Biphasic or triphasic | 22 | |
8155592030 | What dose usually gets changed in a *biphasic or triphasic* combined oral contraceptive? | Progestin gets increased. Estrogen stays the same. | 23 | |
8155592031 | Who isn't allowed to take *combined oral contraceptives*? | Women > 35 who smoke ≥ 15 cigs/day | 24 | |
8155592032 | What can a *Woman older than 35* that *smokes 16 cigs/day* take for oral contraception? | Progestin only preparations | 25 | |
8155592033 | What's the *CV side effect* of oral contraceptives? | Thromboembolism | 26 | |
8155592034 | What is it about *COC* that increases the risk of *thromboembolism*? | Estrogen increases factor VII, X, and fibrinogen production | 27 | |
8155592035 | So, *COC* have a risk of *thromboembolism*. What contraception *does not have this risk*? | Progestin only preparations | 28 | |
8155592036 | What's a *side effect* mainly seen with *norethindrone*? | Hirsutism & acne (Since it's a testosterone derivative & all) | 29 | |
8155592037 | What contraceptive is *derived from spironolactone*? | Drosperinone | 30 | |
8155592038 | What are the *side effects* of *Drospirenone*? | Anti-aldosterone & anti-androgenic effects (It's a mineralocorticoid antagonist, remember?) | 31 | |
8155592039 | What's a *nice side effect* of *COC* use? | 50% decrease in endometrial cancer incidence | 32 | |
8155592040 | What's an annoying *side effect* of *progestin-only contraception*? | Irregular, unpredictable spotting and bleeding | 33 | |
8155592041 | What determines the amount of *estrogen* given in a *COC* starting out? | Weight | 34 | |
8155592042 | What ~specific~ thing do we need to consider when choosing a *contraceptive preparation*? Why? | 19-norprogestin; may have ~androgenic activity~ | 35 | |
8155592043 | What's the difference between *COC & transdermal patch*, as far as blood levels go? | Estrogen can be higher due to skipping first-pass metabolism when using a transdermal patch | 36 | |
8160081849 | Can a *transdermal patch* be as effective as *COCs* in patients under 90kg? | yep | 37 | |
8160112766 | What are the two rare things patients complain about with a *vaginal ring*? | Discomfort. Or worse... expelled | 38 | |
8160186156 | What *two drugs* are typically contained in a *vaginal ring*? | Ethinyl Estradiol & etonogestrel | 39 | |
8160422363 | A mom has just had a baby. She wants to know when she can start taking her BC again. Why are we concerned about *postpartum patients using estrogen-containing COCs*? | Hypercoagulability & effects on lactation | 40 | |
8160432110 | A mom has just had a baby. She wants to know when she can start taking her BC again. When can she *start back on her estrogen-containing COCs*? What can she take in the meantime? | After the first 21 days postpartum; Progestin-only contraceptives | 41 | |
8160477378 | A breastfeeding mom has just had a baby. She has *risk factors for venous thromboembolism.* She wants to know when she can start taking her COCs again. When can she take it? | After 42 days postpartum | 42 | |
8160562566 | A breastfeeding mom has just had a baby. She has *NO risk factors for venous thromboembolism.* She wants to know when she can start taking her COCs again. When can she take it? | 30 days (?) | 43 | |
8160618211 | What drugs are used as *postcoital contraceptives*? | Progestin, estrogen, or combined | 44 | |
8160624955 | What's the advantage of using a *progestin-only postcoital contraceptive*? | Fewer side effects | 45 | |
8160641189 | A woman takes a *postcoital contraceptive* 6 days after to prevent pregnancy. Is she going to be pregnant or nah? | Oh, she's pregnant. Gotta take that within 72 hrs (implantation is 5 days later) | 46 | |
8160661930 | What are the two drugs approved as *emergency contraception*? | Levonorgestrel & Norgestrel | 47 |
B12 Pharm Contraceptives Flashcards
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