B12 Flashcards
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6072543137 | Co enzyme | CH3 (Mehylcobalamin) | 0 | |
6072544670 | Food sources | Meats | 1 | |
6072545591 | DRI | Females & Males: 2.4 ug | 2 | |
6072547322 | Digestion (1-5 steps) | 1. Cleavage of B12 from proteins in stomach (by pepsin & HCl) 2. B12 binds to R protein in stomach 3. B12 is cleaved from R protein in intestine 4. B12 binds to intrinsic factor in intestine 5. B12 complex is absorbed in ileum | 3 | |
6072550356 | Problems with absorption | • Sometimes B12 not released from • R protein (low enzyme levels) • IF (intestinal acidity too high) • Absorption of B12: 11 - 65% | 4 | |
6072552361 | Function | Conversion of homocysteine to methionine | 5 | |
6072554360 | Deficiency | 1.Megalobastic macrocytic anemia 2. Neuropathy (memory loss, dementia) 3. Heart Disease | 6 |