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AP Biology Chapter 12 & 13 Flashcards

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5720418385heredityPassing of traits from parents to offspring0
5720418386variationDifferences in the frequency of genes and traits among individual organisms within a population1
5720418387geneticsThe scientific study of heredity2
5720418388genesDNA segments that serve as the key functional units in hereditary transmission.3
5720418389gametesA haploid cell such as an egg or sperm. Gametes unite during sexual reproduction to produce a diploid zygote.4
5720418390gene locusspecific location of a gene on a chromosome5
5720418391asexual reproductionA reproductive process that involves only one parent and produces offspring that are identical to the parent.6
5720418392cloneAn organism that is genetically identical to the organism from which it was produced7
5720418393sexual reproductionA reproductive process that involves two parents that combine their genetic material to produce a new organism, which differs from both parents8
5720418394life cycleThe entire sequence of stages in the life of an organism, from the adults of one generation to the adults of the next.9
5720418395somatic cellAny cell in a multicellular organism except a sperm or egg cell.10
5720418396karyotypeA display of the chromosome pairs of a cell arranged by size and shape.11
5720418397homologous chromosomesChromosomes that have the same sequence of genes and the same structure12
5720418398sister chromatidsIdentical copies of a chromosome; full sets of these are created during the S subphase of interphase.13
5720418399sex chromosomesThe pair of chromosomes (X & Y) responsible for determining the sex of an individual.14
5720418400autosomesAny chromosome that is not a sex chromosome15
5720418401diploid cellA cell containing two sets of chromosomes (2n), one set inherited from each parent.16
5720418402haploid cellA cell containing only one set of chromosomes (n).17
5720418403fertilizationThe union of haploid gametes to produce a diploid zygote18
5720418404zygoteFertilized egg cell19
5720418405meiosisA modified type of cell division in sexually reproducing organisms consisting of two rounds of cell division but only one round of DNA replication. It results in cells with half the number of chromosome sets as the original cell.20
5720418406alternation of generationsthe alternation between the haploid gametophyte and the diploid sporophyte in a plant's life cycle21
5720418407sporophytesthe multicellular diploid form that results from the union of gametes. The sporophyte produces haploid spores by meiosis that develop into gametophytes22
5720418408spores(1)in the life cycle of a plant or alga undergoing alternation of generations, a haploid cell produced in the sporophyte by meiosis. A spore can divide by mitosis to develop into a multicellular haploid individual, the gametophyte, without fusing with another cell. (2) In fungi, a haploid cell, produced either sexually or asexually, that produces a mycelium after germination.23
5720418409gametophyteThe multicellular haploid form that produces haploid gametes by mitosis.24
5720418410meiosis IHomologous chromosomes separate25
5720418411meiosis IIthe second phase of meiosis consisting of chromatids separating, along with the two diploid cells splitting in two26
5720418412prophase IThe first phase of meiosis I. During prophase I the replicated chromosomes condense, homologous chromsomes pair up, crossing over occurs between homologous chromosomes, the spindle is formed, and the nuclear envelope breaks apart into vesicles. Prophase I is the longest phase of meiosis.27
5720418413metaphase IThe second phase of meiosis I. During metaphase I the paired homologous chromsomes (tetrads) align at the center of the cell (the metaphase plate).28
5720418414anaphase IThe third phase of meiosis I. the replicated homologous chromosomes are separated (the tetrad is split) and pulled to opposite sides of the cell.29
5720418415telophase Ithe fifth and final stage of mitosis, to which daughter nuclei are forming and cytokinesis has typically begun.30
5720418416cytokinesisDivision of the cytoplasm during cell division31
5720418417prophase IIThe first phase of meiosis II. Prophase II is identical to mitotic prophase, except that the number of chromosomes was reduced by half during meiosis I.32
5720418418metaphase IIThe second phase of meiosis II. Metaphase II is identical to mitotic metaphase, except that the number of chromosomes was reduced by half during meiosis I.33
5720418419anaphase IIThe third phase of meiosis II. During anaphase II the sister chromatids are finally separated at their centromeres and pulled to opposite sides of the cell. Note that anaphase II is identical to mitotic anaphase, except the number of chromosomes was reduced by half during meiosis I.34
5720418420Telophase IIThe fourth and final phase of meiosis II. Telophase II is identical to mitotic telophase, except that the number of chromosomes was reduced by half during meiosis. I.35
5720418421daughter cellsThe cells that are produced as a result of mitosis. These cells are identical to each other, and also to the original parent cell.36
5720418422synapsisthe pairing of homologous chromosomes during meiosis37
5720418423crossing overthe reciprocal exchange of genetic material between nonsister chromatids during prophase I of meiosis38
5720418424chiasmaThe X-shaped, microscopically visible region where homologous nonsister chromatids have exchanged genetic material through crossing over during meiosis, the two homologs remaining associated due to sister chromatids cohesion.39
5720418425homologsclosely related genes40
5720418426cohesinsProteins that hold sister chromatids together41
5720418427reductional divisionanother name for meiosis I42
5720418428equatorial divisionMeiosis 243
5720418429allelesDifferent forms of a gene44
5720418430independent assortmentThe random distribution of the pairs of genes on different chromosomes to the gametes.45
5720418431recombinant chromosomesChromosomes that combine genes from both parents due to crossing-over46
5720418432Rudulf VirchowPhysician and biologist who discovered cell division, "All cells come from other cells" or "Omnis cellula e cellula"47
5720418433Cell divisionthe process in reproduction and growth by which a cell divides to form daughter cells, also functions in renewal, repair and growth48
5720418434MetastasisSpread of cancer cells beyond their original site in the body49
5720418435ZygoteThe diploid cell resulting from the union of an ovum and a spermatozoon (including the organism that develops from that cell)50
5720418436Cell CycleThe regular sequence of growth and division that cells undergo.51
5720418437GenomeA cell's total endowment of DNA, in eukaryotes this consists of a large number of DNA molecules, while in prokaryotes it is just a single long molecule.52
5720418438Chromosomesthread like structures that have genetic info (DNA) that is passed down from one generation to the next, make the large amount of DNA that is packaged in them very managable. Are named because of the cewrtain dyes that they take up when used in microscopy.53
5720418439Somatic CellsAny cell in multicellular organism EXCEPT an egg or sperm(gametes), they each contain 46 chromosomes made up of two sets of 23.54
5720418440GametesThey are haploid reproductive cells like sperm cells or egg cells 23 chromosomes.55
5720418441ChromatinLong strands of DNA found in the eukaryotic cell nucleus; condense to form chromosomes and wrapped around histones.56
5720418442HistonesGlobular protein molecule around which DNA is tightly coiled in chromatin, helps in the regulation of the first level of DNA packing57
5720418443Sister ChromatidsEach duplicated chromosome has 2 _____________. , Each conatining an identical DNA molecule attached by adhesve proteins all olong their lengths.58
5720418444Sister ChromatidsIdentical copies of a chromosome; full sets of these are created during the S(DNA replication) subphase of interphase, joined at the middle by the centromere.59
5720418445Centromerea specialized condensed region of each chromosome that appears during mitosis where the sister chromatids are held together to form an X shape60
5720418446MitosisIn eukaryotic cells, a process of cell division that forms two new nuclei, each of which has the same number of chromosomes. 5 Phases61
5720418447CytokinesisOrganic process consisting of the division of the cytoplasm of a cell following karyokinesis bringing about the separation into two daughter cells, involves the formation of cleavage furrow formation.62
5720418448MeiosisProcess by which the number of chromosomes per cell is cut in half through the separation of homologous chromosomes in a diploid cell, leading to nonidentical daughter cells that have only one set of chromosomes and produces reproductive cells.63
5720418449Walther FlemmingGerman scientist who in 1882 developed dyes that allowed him to observe the behavior of chromosomes during mitosis and cytokinesis,64
5720418450Mitotic PhaseA phase of the cell cycle that include both mitosis and cytokinesis, and is the shortest part of the cell cycle, alternates with interphase and is abreviated (M)phase.65
5720418451InterphaseThe longest phase of the cell cycle (accounting for 90% of the cycle), it is during this phase that the cell grows and copies its chromosomes in preparation for cell division, divied into 3 phases ( G1 phase(first gap), S phase(synthesis), and G2 phase(second gap), during this phase the single centrosome replicate but stay near the nucleus.66
5720418452S phaseThe phase( and only phase) of interphase in which cell chromosomes are duplicated67
572041845324A human cell usually undergoes one divisipn every ______ 24 hours. Of this time M phase would last 1 hour, S phase 10-12 hours, and the rest would be split between G1 and G2.68
5720418454G1 PhaseThe most variable in time of the interphase phases depending on the type of cell.69
5720418455Prophase1st Phase of the mitosis where chromatin fiber becomes tightly coiled condensing into chromosomes, the nucleoli disappear, the mitotic spindle begins forming(composed of centrosomes and microtubules), and the centrosomes begin to move away from each other70
5720418456Prometaphase2nd phase of mitosis, where the nucleur envolope fragments, microtubules go through nucleur area and interact with chromosomes, each of the chromatids of the chromosomes has a kinetochore at the centromere which attacth to the microtubules, amd nonkinetochore microtubules interact with those on opposite pole of spindle.71
5720418457Metaphase3rd phase of mitosis, and the longest lasting about 20 minutes, the centrosomes are now at opposite ends of the cell, the chromosomes have now convened at the metaphase plate(imaginary plane that is equidistant between the spindles 2 poles) each chromosomes kinetochore is connected to kinetochore microtubules coming from opposite poles, the entire apparatus is now called a spindle because of its shape.,72
5720418458Anaphase4th Phase of mitosis, and the shortest lasting a few minutes, begins when the two sister chromatids suddenly part, making each one a seperate chromosome, which then begin to move to opposite sides of the cell by making their kinetochore microtubules shorten (centromere first), and the cell elongates, and by the end of this phase the two ends hav equivalent and complete collections of chromosomes.73
5720418459Telophase5th and Final phase of mitosis, where two daughter nuclei start to form , and nuclear envolopes begin to form from the fragments of the parents cell's nuclear envolope and other portion of the endomembrane system, the chromosomes also become less condensed and mitoisis is complete.74
5720418460Mitotic SpindleJoined microtubules and associated proteins that form around the nucleus; pushing the centrioles to opposite ends of the cells, begins to form in the cytoplasm during prophase(1st). When it assembles the other microtubules of the cytoskeleton partially disassemble to help provide the material to build this.75
5720418461CentrosomeA nonmembrane organelle that functions throughout the cell cycle to organize the cell's microtubules , and is for that reaswon that it is also called the (microtubule-organizing center), usually has a pair of centrioles in the middle of it (although these are not essential for reproduction)76
5720418462KinetochoreA structure of proteins that are associated with specific sections of chromosomal DNA, each of the 2 sister chromatids have one,=.77
5720418463AstersStarlike arrangement of microtubules around the poles of the spindles78
5720418464Metaphase PlateAn imaginary plane during metaphase in which the centromeres of all the duplicated chromosomes are located midway between the two poles79
5720418465Cleavage FurrowThe first sign of cytokinesis during cell division in an animal cell; a shallow groove in the cell surface near the old metaphase plate80
5720418466TubulinIn Anaphase, kinetochore microtubules shorten at their kinetochore ends NOT at their spindle pole ends, because as a microtubule depolarizes at its kineochore end it releases _______ subunits.81
5720418467MicrofilamentsThe ___________made up of a ring of contractile actin and myosin proteins are on the cytoplasmic side of the cleavage furrow, pull on each other and deepen until the two cells have seperated, these _________ are also important in muscle contraction. (Only in Animal Cytokinesis)82
5720418468Cell PlateA double membrane across the midline of a dividing plant cell, between which the new cell wall forms during cytokinesis. Actually derived from vesicles of the golgi apparatus which move to the middle os the cell wall and then coalesce forming the __________.83
5720418469Binary FissionType of asexual reproduction in prokaryotes which an organism replicates its DNA and divides in half, producing two identical daughter cells84
5720418470Origin of ReplicationThe specific location on a DNA strand where replication begins.. Prokaryotes typically have a single origin of replication, while eukaryotes have several per chromosome.85
5720418471Liver CellsDetoxify poisonous substances like bacteria & certain drugs, reseve the ability to divide until it needs to.86
5720418472Cell Cycle control systemA cyclically operating set of molecules in the cell that triggers and coordinates key events in the cell cycle. is regulated at certain "checkpoints" like G1, G2 and M1.87
5720418473CheckpointA specific point where stop and go signals can regulate the cell cycle.88
5720418474G1 CheckpointThe most important checkpoint, dubbed the restriction point in "mammalian cells" if as cell recieves the go ahead it will usually complete all other parts of the cell cycle.and divide, but if it doesn't it will enter the nondividing G0 phase89
5720418475G0 phasea non dividing face of the cell cycle consisting of the portion of interphase before DNA synthesis begins(Most cells of the human body are actually in this phase) For Example: Nerve cells, muscle cells, and liver cells.90
5720418476CdksEnzymes in an inactive form that are present in consistent concentrations over the cell cycle; *most significant enzyme in regulating cell cycle91
5720418477CyclinsA group of proteins whose function is to regulate the progression of a cell through the cell cycle and whose concentrations rise and fall throughout the cell cycle, attach to kinase(which are at constant concentration)92
5720418478MPFMaturation-promoting factor (M-phase-promoting factor); a protein complex required for a cell to progress from late interphase to mitosis. The active form consists of cyclin and a protein kinase. The first Cdk complex that was discovered first., Causes the phosphoryladtion of various proteins of the nuclear lamina.93
5720418479MitogenA substance which increases mitosis; causes a general cell response to a growth signal, such as platelet derived growth factor(PDGF)94
5720418480PDGFA mitogen( growth factor) that is made by blood cells called platelets,is required for the division of fibrolasts in culture(As they have these receptors (which are tryosine kinase) in their plamsa membrane95
5720418481FibroblastsThe type of connective tissue cell that is the most numerous. It secretes fibers and components of the ground substance of the matrix, has receptor molecules in their plasma membrane that are tyrosine kinase which have to bind to PDGF in order to divide.96
5720418482Density - dependent InhibitionAn external physical factor and phenomena that explains why crowded cells stop dividing, means that the amount of growth factor and nutrients per cewll are more important than number of cells, and when the population of a group of cells reaches a certain density it becomes insufficientto allow cell growth and divison.97
5720418483Anchorage DependenceThe requirement that a cell must be attached to a substratum in order to divide, experiments have suggested that this type of dependence is signaled into the cell cycle via pathways controling plasma membrane proteins and elements of the cytoskeleton linked to them98
5720418484HeLa CellsCultured cells from cancer patient Henrietta Lacks from 1951 that continue to divide quntil today . they have an immortal cell line and are used to study cancer, actually used by Jonas Salk to test his polio vaccine.99
5720418485TransformationThe process by which a normal cell is converted into a cancer cell, the first step of cencer.100
5720418486TumorA mass of abnormal cells that are within otherwise normal tissue. Must secrete signal molecules that cause blood vessels to grow towards the tumor101
5720418487Benign TumorA mass of abnormal cells that remains at the site of origin, do not cause serious problems.102
5720418488Malignant TumorA cancerous tumor that is invasive enough to impair the functions of one or more organs., usually either poliferate to much , metastaze or have an abnormal amount of chromosomes.103
5720418489ChemotherapyThe type of treatment that is frequently used with cancer that is non-local, but that has to be limited becasue of the danger that it can have on your body, is used in total with drugs like Taxol which freezes mitotic spindle by preventing microtuble depolymerization.104
5720418490TaxolAnti-cancer drug that prevents depolymerization of microtubules whish effectively stops the cell cycle., found in the bark of pacific yew trees.105

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