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AP Biology Chapter 16 Flashcards

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5726173470DNA Replicationthe process by which a DNA molecule is copied; also called DNA synthesis0
5726173471Transformationa change in genotype and phenotype due to the assimilation of external DNA by a cell transforming substance- DNA1
5726173472BacteriophagesViruses that infect bacteria Bacteria eaters2
5726173473Virusinfects a cell and takes over the cell's metabolic machinery3
5726173474Hershey and Chase (Don't need to memorize scientists)Concluded that phage DNA entered bacterial host cells, but phage proteins did not, so DNA functions as the genetic material4
5726173475Griffith (Don't need to memorize scientists)Concluded that nonpathogenic bacteria transformed into pathogenic bacteria by an unknown, heritable substance from the dead S cells that enabled the R cells to make capsules5
5726173476Chargaff's Lawthe base compostion of DNA varies between species and for each species, the percentages of A and T bases are roughly equal to the percentages of the G and C bases6
5726173477Rosalind Franklin (Don't need to memorize scientists)accomplished X-ray crystallographer that discovered the double helix of DNA7
5726173478Antiparallelsubunits run in opposite directions8
5726173479Nitrogenous bases of DnaA, T, C, G9
5726173480PurinesA and G Nitrogenous bases with two organic rings10
5726173481PyrimidinesC and T Nitrogenous base with a single organic ring11
5726173482Conservative modeltwo parental strands reassociate after acting as templates for new strands thus restoring the parental double helix12
5726173483Semiconservative Modelthe two strands of the parental molecule separate and each functions as a template for synthesis of a new complementary strand- most common13
5726173484Dispersive Modeleach strand of both daughter molecules contains a mixture of old and newly synthesized DNA14
5726173485Origins of Replicationshort stretches of DNA having a specific sequence of nucleotides15
5726173486Replication Forka Y shaped region where the parental strands of DNA are being unwound16
5726173487Helicasesenzymes that untwist the double helix at the replication forks, separating the two parental strands and make them available as template strands17
5726173488Single Strand Binding ProteinsBind to the unpaired DNA strands keeping them from repairing18
5726173489TopoisomeraseThe untwisting of double helix causes tighter twisting and strain ahead of replication fork Relieve this strain by breaking swiveling, and rejoining DNA strands19
5726173490PrimerThe initial nucleotide chain that is produced during DNA synthesis is actually a short stretch of RNA20
5726173491PrimaseSynthesizes the primer Starts a complementary RNA chain from a single RNA nucleotide, adding more RNA nucleotides one at a time, using the parental DNA strand as a template21
5726173492DNA polymerasesEnzyme that catalyze the synthesis of new DNA by adding nucleotides to a preexisting chain22
5726173493Leading strandStrand that continuously adds nucleotides to the new complementary strand as the fork progresses DNA pol III23
5726173494Lagging StrandThe strand that DNA pol III works away from the replication fork Synthesized discontinuosly as a series of segments24
5726173495Okazaki fragmentsSeries of segments that are 1000-2000 nucleotides long25
5726173496DNA Ligasejoins the sugar phosphate backbones of all the Okazaki fragments into a continuous DNA strand26
5726173497DNA pol IIISynthesizes new DNA strands by adding nucleotides to an RNA primer or a pre-existing DNA strand27
5726173498DNA pol IRemoves RNA nucleotides of primer from 5' end and replaces them with DNA nucleotides28
5726173499Mismatch repairOther enzymes remove and replace incorrectly paired nucleotides that have resulted from replication errors29
5726173500NucleaseDNA cutting enzyme that cuts out the damaged parts of the strand and fills the space with nucleotides using the undamaged strand as a template30
5726173501Nucleotide excision repairDNA repair system where teams of enzymes detect and repair the DNA, the nuclease cuts out the damaged DNA and removes it, fills in the missing nucleotides and the DNA ligase seals the free end of the new DNA to the old DNA making the strand complete31
5726173502TelomeresSpecial nucleotide sequences at the ends of chromosomes TTAGGG is repeated between 100-1000 times Prevent the staggered ends of daughter molecule from activitating cell's system for monitoring DNA damage32
5726173503TelomeraseEnzyme that catalyzes the lengthening of telomeres in eukaryotic germ cells and restores the original length and compensating for the shortening that occurs during DNA replication33
5726173504HistonesProteins that are responsible for the first level of DNA packing in chromatin34
5726173505Nucleosomethe basic unit of DNA packing35
5726173506Chromatincomplex of DNA and protein36
5726173507Heterochromatincentromeres and telomeres exist in a highly condensed state with visible irregular clumps making it largely inaccessible37
5726173508Euchromatincentromeres and telomeres exist in a less compacted state that is very accessible38

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