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AP Biology chapter 16 Key terms Flashcards

16: The molecular basis of inheritance

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526274578bacteriophageA virus that infects bacteria; also called a phage. See phage.
526274579DNA ligaseA linking enzyme essential for DNA replication; catalyzes the covalent bonding of the 39 end of a new DNA fragment to the 59 end of a growing chain.
526274580DNA polymeraseAn enzyme that catalyzes the elongation of new DNA at a replication fork by the addition of nucleotides to the existing chain.
526274581double helixThe form of native DNA, referring to its two adjacent polynucleotide strands wound into a spiral shape.
526274582helicaseAn enzyme that untwists the double helix of DNA at the replication forks.
526274583lagging strandA discontinuously synthesized DNA strand that elongates in a direction away from the replication fork.
526274584leading strandThe new continuous complementary DNA strand synthesized along the template strand in the mandatory 5' 3' direction.
526274585mismatch repairThe cellular process that uses special enzymes to fix incorrectly paired nucleotides.
526274586nucleaseA team of enzymes that hydrolyze DNA and RNA into their component nucleotides.
526274587nucleotide excision repairThe process of removing and then correctly replacing a damaged segment of DNA using the undamaged strand as a guide.
526274588origins of replicationSites where the replication of a DNA molecule begins.
526274589phageA virus that infects bacteria; also called a bacteriophage.
526274590primaseAn enzyme that joins RNA nucleotides to make the primer.
526274591primerAn already existing RNA chain bound to template DNA to which DNA nucleotides are added during DNA synthesis.
526274592replication forkA Y-shaped region on a replicating DNA molecule where new strands are growing.
526274593semiconservative modelType of DNA replication in which the replicated double helix consists of one old strand, derived from the old molecule, and one newly made strand.
526274594single-strand binding proteinDuring DNA replication, molecules that line up along the unpaired DNA strands, holding them apart while the DNA strands serve as templates for the synthesis of complimentary strands of DNA.
526274595telomeraseAn enzyme that catalyzes the lengthening of telomeres. The enzyme includes a molecule of RNA that serves as a template for new telomere segments.
526274596telomereThe protective structure at each end of a eukaryotic chromosome. Specifically, the tandemly repetitive DNA at the end of the chromosome's DNA molecule. See also repetitive DNA.
526274597transformation(1) The conversion of a normal animal cell to a cancerous cell. (2) A change in genotype and phenotype due to the assimilation of external DNA by a cell.

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