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AP Biology Chapter 17 Flashcards

From Gene to Protein

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9277104737Gene Expressionprocess by which DNA directs synthesis of proteins0
9277104738Transcription-synthesis of RNA under direction of DNA -DNA serves as template for assembling complementary RNA molecule -resulting RNA molecule faithful transcript of gene's protein-building instructions -occurs in nucleus1
9277104739Messenger RNA (mRNA)RNA molecule that carries genetic message from DNA to protein synthesizing machinery of cell2
9277104740Translation-synthesis of polypeptide -occurs under direction of mRNA -change in language-cell must translate base sequence of mRnA molecule into amino acid sequence of polypeptide -occurs in cytoplasm3
9277104741Ribosomes-sites of translation -complex particles that facilitate orderly linking of amino acids into polypeptide chains4
9277104742Primary Transcriptinitial RNA transcript from any gene, including those coding for RNA that is not translated into protein5
9277104743Triplet Codegenetic instructions for polypeptide chain written in DNA as series of non-overlapping, 3 nucleotide words6
9277104744Template StrandDNA strand that provides pattern/template for sequence of nucleotides in RNA transcript7
9277104745CodonsmRNA base triplets written 5'-3' direction8
9277104746Reading Framegrapings w/ symbols w/ message that needs to be translated to written language9
9277104747RNA Polymerase-pries 2 strands of DNA apart -joins RNA nucleotides as they base pair along DNA template -assemble polynucleotides 5' -> 3' -can start chain from scratch-no primer needed10
9277104748PromoterDNA sequence where RNA polymerase attaches and initiates transcription11
9277104749Terminatorsequence that signals end of transcription in bacteria12
9277104750Transcription Unitstretch of DNA transcribed into RNA molecule13
9277104751Transcription FactorsA regulatory protein that binds to DNA and affects transcription of specific genes14
9277104764Transfer RNA (tRNA)transfer amino acids from cytoplasmic pool of AA to ribosome15
9277104765Anticodonnucleotide triplet that base pairs of complementary codon of mRNA16
9277104768Ribosomal RNA (rRNA)made in nucleolus, make up ribosomal subunits17
9277104770A Site (aminoacyl-tRNA site)holds tRNA carrying next AA to be added in chain18
9277104771E Site (exit site)where discharged tRNAs leave ribosome19
9277104772Release Factorprotein that binds to stop codon @ A site20
9277104774Signal Peptide-targets protein to ER -marks if polypeptide of proteins destined for endomembrane system or for secretion21
9277104777Mutations-change into genetic information of a cell -responsible for huge diversity of genes found among organisms22
9277104778Point Mutationschanges in a DNA sequence caused by substitution of one nucleotide for another23
9277104779Base Pair Substitutionsreplaces one nucleotide and its partner with another pair of nucleotides24
9277104780Missense MutationsA base-pair substitution that results in a codon that codes for a different amino acid.25
9277104781Nonsense MutationChanges a normal codon into a stop codon26
9277104782Insertionsadditions of nucleotide pairs in gene27
9277104783Deletionlosses of nucleotide pairs in gene28
9277104784Frameshift MutationsShift the reading frame of the genetic message by adding or deleting a nucleotide29
9277104785Mutagenphysical and chemical agents that interact w/ DNA that cause mutations30
9277104786rRNAribosomal RNA; type of RNA that makes up part of the ribosome31
9277104787geneequals one RNA molecule A segment of DNA on a chromosome that codes for a specific trait32
9277160900P siteholds tRNA carrying growing polypeptide chain33

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