Viruses
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| 8743891372 | Virus | -smaller and simpler than eukaryotes and prokaryotes -cannot reproduce/carry out metabolic activity outside host cell |  | 0 |
| 8743891373 | Capsid | -protein shell enclosing viral genome -built from capsomere protein subunits -usually have few types of proteins making up capsid | 1 | |
| 8743891374 | Viral Envelopes | -membranous envelope surrounding capsids of many animal viruses -derived from membranes of host cells -contain host cell phospholipids and membrane proteins -contain viral proteins and glycoproteins | 2 | |
| 8743891375 | Bacteriophage (Phage) | -viruses that infect bacteria -capsids w/ elongated icosahedral heads w/ DNA -protein tail piece w/ fibers by which phages attach to bacterium attached to head |  | 3 |
| 8743891376 | Host Range | limited variety of host cells each type of virus can affect, determine by lock and key | 4 | |
| 8743891377 | Viral Reproduction | 1. virus binds to host cell and enters uncoated, releasing viral DNA and capsid proteins 2. viral genome encodes proteins to have host reprogram cell to copy viral nucleic acid and replicate viral genome 3. meanwhile, host enzymes transcribe viral genome into viral mRNA, which host ribosomes use to make more capsid proteins 4. viral genomes and capsid proteins self-assemble into new virus particles, which exit cell to infect other cells and spread viral infection |  | 5 |
| 8743891378 | Lytic Cycle | -phage reproductive cycle that culminates in death of host cell 1. Attachment: page uses tail fibers to bind to specific receptor sites on surface bacteria 2. Entry of phage DNA and degradation of host DNA: sheath of tail contracts, injecting the phage DNA into cell and leaving empty capsid outside -> cells DNA hydrolyzed 3. Synthesis of viral genomes and proteins: phage DNA directs production of phage proteins and copies of phage genome w/ host enzymes 4. Assembly: 3 separate sets of proteins self-assemble to form phage heads, tails, and tail fibers; genome packaged in capsid as head forms 5. Release: phage directs production of enzyme that damages bacterial cell wall -> fluid enters -> cell swells and bursts, releasing 100-200 phage particles |  | 6 |
| 8743891379 | Virulent Phage | phage that reproduces only by lytic cycle | 7 | |
| 8743891380 | Lysogenic Cycle | phage reproductive cycle w/ replication of phage genome w/o destroying host 1. phage DNA incorporated on site of bacterial chromosome -> prophage 2. bacterium reproduces normally, copying prophage and transmitting it to daughter cells 3. many cell divisions -> large population of infected bacteria |  | 8 |
| 8743891381 | Temperate Phage | phage capable of using both modes of reproduction (lytic and lysogenic) in bacteria | 9 | |
| 8743891382 | Prophage | phage DNA incorporated into bacterial DNA |  | 10 |
| 8743891384 | Retrovirus (Class VI) | -RNA animal virus w/ most complex reproductive cycles -have reverse transcriptase enzyme | 11 | |
| 8743891385 | Reverse Transcriptase | enzyme that transcribes RNA template to DNA | 12 | |
| 8743891386 | HIV | -Human Immunodeficiency Virus -retrovirus causing AIDS | 13 | |
| 8743891387 | AIDS | Acquired Immunodeficiency Syndrome | 14 | |
| 8743891389 | Vaccine | harmless variant of pathogen that stimulates immune system to mount defenses against harmful purposes | 15 | |
| 8743891390 | Emerging Viruses | viruses that are new to medical scientists/suddenly appear b/c: 1. mutation of existing viruses -> new strains of disease -> epidemics 2. dissemination of viral disease from small, isolated human population-can be due to technological and social factors (radiation, travel, blood transfusion, sexual promiscuity, drugs, etc...) 3. spread of existing virus from other animals | 16 | |
| 8743891391 | Epidemic | huge outbreak of disease | 17 | |
| 8743891392 | Pandemic | global epidemic | 18 | |
| 8743891393 | Viroid | -circular RNA molecules that infect plants -replicate in host plant cells using host enzymes instead of encoding proteins -cause errors in regulatory system that control plant growth -> stunted growth, abnormal development | 19 | |
| 8743891394 | Prion | -infection proteins that cause many degenerative brain diseases of many animals -mostly transmitted w/ food-incubation 10+ years -virtually indestructible propagate by: -misfolded versions of normal brain proteins -contact w/ normal folded protein -> normal gets abnormal shape -chain rxn of misfolding -> cellular malfunction, brain degeneration | 20 |
