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AP BIology DNA Replication, Cell Cycle (Mitosis) AP Biology Flashcards

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8170644088DNA Replicationthe process by which a DNA molecule is copied; also called DNA synthesis0
8170644089Antiparallelsubunits run in opposite directions1
8170644090Semiconservative Modelthe two strands of the parental molecule separate and each functions as a template for synthesis of a new complementary strand- most common2
8170644091Replication Forka Y shaped region where the parental strands of DNA are being unwound3
8170644092Helicasesenzymes that untwist the double helix at the replication forks, separating the two parental strands and make them available as template strands4
8170644093Single Strand Binding ProteinsBind to the unpaired DNA strands keeping them from repairing5
8170644094TopoisomeraseThe untwisting of double helix causes tighter twisting and strain ahead of replication fork Relieve this strain by breaking swiveling, and rejoining DNA strands6
8170644095PrimerThe initial nucleotide chain that is produced during DNA synthesis is actually a short stretch of RNA7
8170644096PrimaseSynthesizes the primer Starts a complementary RNA chain from a single RNA nucleotide, adding more RNA nucleotides one at a time, using the parental DNA strand as a template8
8170644097DNA polymerase IIIThe main enzyme that catalyze the synthesis of a new DNA strand by adding nucleotides to a preexisting chain9
8170644098Leading strandStrand that continuously adds nucleotides to the new complementary strand as the fork progresses10
8170644099Lagging StrandThe strand that DNA polymerase III builds moving away from the replication fork Synthesized discontinuosly as a series of segments11
8170644100Okazaki fragmentsSeries of segments that are 1000-2000 nucleotides long. Made due to the discontinuous building of the lagging strand.12
8170644101DNA Ligasejoins the sugar phosphate backbones of all the Okazaki fragments and replaced primers into a continuous DNA strand13
8170644102DNA polymerase IRemoves RNA nucleotides of primer from 5' end and replaces them with DNA nucleotides14
8170644103Chromatincomplex of DNA and protein15
8170644104Prophase Metaphase Anaphase TelophaseWhat are the four stages of mitosis?16
8170644105prophaseWhich phase? the first stage of mitosis, in which the chromatin condenses into discrete chromosomes visible with a light microscope, the mitotic spindle begins to form, and the nucleolus disappears but the nucleus remains intact.17
8170644106MetaphaseWhich Phase? The second stage of mitosis, in which the spindle is complete and the chromosomes, attached to microtubules at their kinetochores, are all aligned at the metaphase plate.18
8170644107anaphaseWhich phase?-the third stage of mitosis, in which the chromatids of each chromosome have separated and the daughter chromosomes are moving to the poles of the cell.19
8170644108telophaseWhich phase?-The fourth and final stage of mitosis, in which daughter nuclei are forming and cytokinesis has typically begun.20
8170644109CytokinesisWhich phase is when there is division of the cytoplasm to form two separate daughter cells immediately after mitosis.21
8170644110Sister ChromatidsTwo copies of a duplicated chromosome attached to each other by proteis at the centromere and sometimes, along the arms. While joined, two sister chromatids make up one chromosome. Chromatids are eventually separated during mitosis or meiosis II22
8170644111InterphaseWhich Phase?-The period in the cell cycle when the cell is not dividing. During interphase, cellular metabolic activity is high, chromosomes and organelles are duplicated, and cell size may increase. Interphase often accounts for about 90% of the cell cycle.23
8170644112SpindleAn assemblage of microtubules and associated proteins that is involved in the movement of chromosomes during mitosis.24
8170644113Growth of a multicellular organism Replacement/Repair of cellsWhat are two roles of Mitosis?25
8170644114G1, S, G2What are the Phases of the Interphase?26
8170644115DNA replication.What happens in the S Phase?27
8170644116G2This third subphase of interphase is a period of metabolic activity and growth. During this phase the cell makes final preparations for division.28
8170644117G1This is the portion of the cell cycle just after division, but before DNA synthesis. During this time the cell grows by producing proteins and organelles.29
8170644118cytoplasm divides in two.What happens during cytokinesis?30
8170644119Difference between mitosis and cytokinesisWhat does this describe? Cell division consists of two processes: mitosis and cytokinesis. Mitosis— division of the nucleus and its chromosomes— is divided into five phases: prophase, prometaphase, metaphase, anaphase, and telophase. Mitosis is followed by cytokinesis, when the cytoplasm splits to form two separate daughter cells.31
81706441201. The nucleoli disappear 2. Chromatin fibers coil up to become discrete chromosomes. 3. Each chromosome consists of two identical sister chromatids, joined at the centromere. 4. Spindle starts to formWhat happens during prophase?32
8170644121Spindle moves chromosomes. Chromosomes move to the metaphase plate (MIDDLE), an imaginary plane equidistant from the poles.What happens during metaphase?33
8170644122The two centromeres of each chromosome come apart, separating the sister chromatids.What happens during anaphase?34
81706441231. nuclear envelopes form around the identical sets of chromosomes at the two poles of the cell.What happens during Telophase?35
8170644124Membrane pinches inHow does cytokinesis happen in animal cells?36
8170644125Cell plate forms new cell wallHow does cytokinesis happen in plant cells?37
8170644126Cleavage FurrowThe first sign of cleavage in an animal cell; a shallow groove around the cell in the cell surface near the old metaphase plate.38
8170644127a centromereThe region of a chromosome holding the two double strands of replicated DNA together is called _____.39
8170644128sister chromatids are attached to one anotherThe centromere is a region in which _____.40
8170644129Proto-oncogeneA gene that causes cell division to occur when it should. When mutated, it can become an oncogene allowing for more cell division than needed.41
8170644130Tumor Suppressor GeneA gene that either stops cell division or destroys damaged cells.42
8170644131MetastasisWhen cancer cells break away from their origin and spread to a different part of the body.43
8170644132MalignantMeans "mean" or harmful to other cells.44
8170644133TelomeraseAn enzyme that adds to the ends of chromosomes so that they do not shorten during replication45
8170644134During G1, mitosis (before anaphase) and G2When are checkpoints in the cell cycle?46
8170644135CdK (cyclin dependent kinase) and cyclin.What are the 2 components of MPF (maturation promotion factor)?47
8170644136CyclinWhat substance builds up during interphase to later bind with CdK (cyclin dependent kinase)?48
8170644137MPFCauses Mitosis to start.49
8170644138Benignmeans "nice" or not harmful to other cells.50

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