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AP BIology DNA Replication Flashcards

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9352859012DNA Replicationprocess by which DNA molecule is copied; DNA synthesis (S stage of interphase)0
9352859013Transformationa change in genotype and phenotype due to the assimilation of external DNA by bacteria1
9352859014BacteriophagesViruses that infect bacteria Bacteria eaters2
9352859015Virusinfects a cell and takes over the cell's metabolic machinery3
9352859016Hershey and ChaseConcluded that viral DNA entered bacterial host cells, but viral proteins did not, so DNA fis the genetic material4
9352859017Chargaff's Lawthe base compostion of DNA varies between species and for each species, the percentages of A and T bases are roughly equal to the percentages of the G and C bases5
9352859018Rosalind FranklinX-ray crystallographer that discovered the double helix of DNA6
9352859019Watson and Crickdiscovered the structural double helix model of DNA7
9352859020Double helixtwo twisted strands8
9352859021Antiparallelsubunits run in opposite directions9
9352859022Nitrogenous bases of DnaA, T, C, G10
9352859023PurinesA and G Nitrogenous bases with two organic rings11
9352859024PyrimidinesC and T Nitrogenous base with a single organic ring12
9352859025Semiconservative Modelthe two strands of the parental molecule separate and each functions as a template for synthesis of a new complementary strand- most common13
9352859026Origins of Replicationshort stretches of DNA having a specific sequence of nucleotides14
9352859027Replication Forka Y shaped region where the parental strands of DNA are being unwound15
9352859028Helicasesenzymes that untwist the double helix at the replication forks, separating the two parental strands and make them available as template strands16
9352859029TopoisomeraseThe untwisting of double helix causes tighter twisting and strain ahead of replication fork Relieve this strain by breaking swiveling, and rejoining DNA strands17
9352859030Leading strandStrand that continuously adds nucleotides to the new complementary strand as the fork progresses18
9352859031Lagging StrandThe strand that DNA polymerase works away from the replication fork; Synthesized discontinuosly as a series of segments19
9352859032Okazaki fragmentsSeries of segments that are 1000-2000 nucleotides long20
9352859033DNA Ligasejoins the sugar phosphate backbones of all the Okazaki fragments into a continuous DNA strand21
9352859034DNA polymeraseSynthesizes new DNA strands by adding nucleotides to a pre-existing DNA strand22
9352859035Mismatch repairOther enzymes remove and replace incorrectly paired nucleotides that have resulted from replication errors23
9352859036NucleaseDNA cutting enzyme that cuts out the damaged parts of the strand and fills the space with nucleotides using the undamaged strand as a template24
9352859037Nucleotide excision repairDNA repair system where teams of enzymes detect and repair the DNA, the nuclease cuts out the damaged DNA and removes it, fills in the missing nucleotides and the DNA ligase seals the free end of the new DNA to the old DNA making the strand complete25
9352859038TelomeresSpecial nucleotide sequences at the ends of chromosomes TTAGGG is repeated between 100-1000 times Prevent the staggered ends of daughter molecule from activitating cell's system for monitoring DNA damage26
9352859039HistonesProteins that are responsible for the first level of DNA packing in chromatin27
9352859040Nucleosomethe basic unit of DNA packing28
9352859041Chromatincomplex of DNA and protein29
9352859042plasmidsmall circular DNA strand in the cytoplasm of a bacterium30
9352859043Avery, McCarty, McLeod experimentProtein- and RNA-degrading enzymes had little effect on transformation, but enzymes that degrade DNA eliminated the transforming activity.31
9352859045complementary32
9352859044retrovirusRNA virus; uses reverse transcriptase enzyme to produce DNA from its RNA genome33
9352859046nucleotide34

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