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AP Biology- Gene Regulation Flashcards

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6247440095operonconsist of a promoter, an operator, and a cluster of genes that control gene regulation in a common pathway, "on and off" switches0
6247440096repressible operonoperon that is normally on because the repressor is inactive1
6247440097inducible operonoperon that is normally off because the repressor is active2
6247440098structural genegenes to be expressed3
6247440099operatora segment of DNA in the promoter region that acts as an on or off "switch"4
6247440100repressora protein that binds to the operator to switch the operon off5
6247440101inducerinactivates the repressor (turns on the operon)6
6247440102regulatory genecodes for the production of the repressor protein and is found upstream of the operon7
6247440103corepressorworks with the repressor to turn off the operon8
6247440104catabolite activator protein (CAP)activator of transcription, binds to cAMP (cyclic adenosine monophosphate) when sugar is scarce which *increases the affinity of RNA polymerase and accelerates transcription of lactose*9
6247440105cellular differentiationthe formation of cells that are specialized in structure and function10
6247440106histone acetylationthe process of acetyl groups attaching to histone tails (opens up chromatin structure)11
6247440107DNA methylationadding a methyl group to cytosine bases during replication, associated with inactivation of genes and reduced transcription12
6247440108enhancergroups of distal control elements located upstream of downstream from a gene or within an intron13
6247440109activatora specific protein that binds to an enhancer to stimulate gene transcription14
6247440110transcription factorssome act as repressors by blocking the binding of activators or binding to an enhancer15
6247440111RNA interferencethe phenomenon of inhibition of gene expression by non-coding RNA molecules (a technique used to silence the expression of selected genes)16
6247440112RNA polymerasean enzyme that links ribonucleotides into a growing RNA chain during transcription17
6247440113miRNAa.k.a. microRNA, associates with one or more proteins in a complex that can degrade or prevent translation of an mRNA with a complementary sequence18
6247440114siRNAa.k.a. small interfering RNA, associates with one or more proteins in a complex that can degrade or prevent translation of an mRNA with a complementary sequence19
6247440115cytoplasmic determinantsa maternal substance that when placed into an egg influences the course of early development by regulating the expression of genes that affect the developmental fate of cells20
6247440116inductionthe process in which one group of embryonic cells influences the development of another, usually by causing changes in gene epression21
6247440117morphogenesisthe cellular and tissue based processes by which an animal body takes shape22
6247440118proto-oncogenea normal cellular gene that has the potential to become an oncogene23
6247440119ras genea gene that codes for Ras (a G protein that relays a growth signal from a growth factor receptor on the plasma membrane to a cascade of protein kinases) ultimately resulting in stimulation of the cell cycle24
6247440120tumor suppressor genea gene whose protein product inhibits cell division thereby preventing the uncontrolled cell growth that contributes to cancer25
6247440121p53 genea tumor suppressor gene that codes for a specific transcription factor that promotes the synthesis of proteins that inhibit the cell cycle26
6247440122negative feedbackinhibits expression27
6247440123positive feedbackactivates expression28
6247440124feedback inhibitionconcentration of substances present in cell either inhibit or activate expression29
6247440125cataboliclac operon30
6247440126anabolictrp operon31
6247440127heterochromatinharder transcription initiation32
6247440128epigeneticsthe field of science that studies heritable changes caused by the activation and deactivation of genes without any change in the underlying DNA sequence of the organism33
6247440129epigenomethe chemical compounds that modify or mark the DNA and change the way genes are expressed34
6247440130alternative DNA splicingproduces different mRNA molecules when different segments of the mRNA are chosen as introns or exons35
6247440131chromatin modificationpromotes the formation of heterochromatin in certain regions blocking transcription36
6247440132cell divisionthe production of large numbers of cells37
6247440133determinationthe condition in which a cell is irreversibly committed to its fate, even if it has not developed its final structure38
6247440134pattern formationthe development of a spatial organization of tissues and organs into their locations under the control of body plan genes39
6247440135positional informationmolecular cues provided by cytoplasmic determinants and inductive signals40
6247440136HOX genes (homeotic genes)primary genes responsible for head to toe formation41
6247440137oncogenescancer causing cells42
6247440138amplificationincreasing the number of copies of the gene43
6247440139tumor virusesviruses that insert their DNA into the host DNA near a proto-oncogene44
6247440140ectodermskin/nervous system45
6247440141mesodermmuscles46
6247440142endodermdigestive system47

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