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AP Biology Genetics Flashcards

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6520879871crossing overProcess in which homologous chromosomes exchange portions of their chromatids during meiosis.0
6520879872independent assortmentOne of Mendel's principles that states that genes for different traits can segregate independently during the formation of gametes1
6520879873segregation(genetics) the separation of paired alleles during meiosis so that members of each pair of alleles appear in different gametes2
6520879874random fertilizationsource of genetic variation caused by the unlimited number of possible sperm & egg combinations3
6520879875homozygousAn organism that has two identical alleles for a trait4
6520879876heterozygousAn organism that has two different alleles for a trait5
6520879877monohybrid crossA cross between individuals that involves one pair of contrasting traits6
6520879878dihybrid crossA cross between two individuals, concentrating on two definable traits7
6520879879alleleAn alternative form of a gene.8
6520879880geneA discrete unit of hereditary information consisting of a specific nucleotide sequence in DNA (or RNA, in some viruses). Codes for RNA, polypeptides, and proteins9
6520879881synapsisPairing of homologous chromosomes10
6520879882dominant alleleAn allele that will determine phenotype if just one is present in the genotype11
6520879883recessive alleleAn allele that is masked when a dominant allele is present12
6520879884phenotypeAn organism's physical appearance, or visible traits.13
6520879885genotypeAn organism's genetic makeup (alleles for a particular gene)14
6520879886test crossthe crossing of an individual of unknown genotype with a homozygous recessive individual to determine the unknown genotype15
6520879887rule of multiplicationA statistical rule stating that the probability of two independent events occuring together is the product of their individual probabilities.16
6520879888rule of additionA statistical rule stating that the probability of either of two indpendent (and mutually exclusive) events ocuring is the sum of their individual probabilities minus the probability of them both occuring together.17
6520879889complete dominanceA relationship in which one allele is completely dominant over another18
6520879890incomplete dominanceA type of inheritance in which two contrasting alleles contribute to the individual a trait not exactly like either parent; blending inheritance.19
6520879891codominanceBoth alleles are equally expressed20
6520879892multiple allelesthree or more forms of a gene that code for a single trait (but each individual only has 2)21
6520879893pedigreeA diagram that shows the occurrence of a genetic trait in several generations of a family22
6520879894cystic fibrosisan autosomal recessive disorder creating thick sticky mucus which is hard to expel23
6520879895Tay-SachsA human genetic disease caused by a recessive allele for a dysfunctional enzyme, leading to accumulation of certain lipids in the brain. Seizures, blindness, and degeneration of motor and mental performance usually become manifest a few months after birth.24
6520879896Sickle CellA human genetic disease of red blood cells caused by the substitution of a single amino acid in the hemoglobin protein; creating sickle shaped red blood cells that collect in vessels causing pain and reduced gas exchange25
6520879897lethal dominant allelehaving a single dominant allele results in death26
6520879898Huntington's diseaseprogressive hereditary disorder characterized by uncontrolled movements- changes in cortex & cerebellum27
6520879899sex-linked genesa gene that is carried on the X or Y chromosome28
6520879900X chromosomeThe sex chromosome found in both men and women. Females have two X chromosomes; males have one. An X chromosome from each parent produces a female child.29
6520879901Y chromosomeThe sex chromosome found only in males. When paired with an X chromosome from the mother, it produces a male child30
6520879902Duchenne muscular dystrophyA human genetic disease caused by a sex-linked recessive allele; characterized by progressive weakening and a loss of muscle tissue.31
6520879903HemophiliaA sex-linked hereditary disease where blood does not coagulate to stop bleeding32
6520879904X-inactivationa process by which one of the two copies of the X chromosome present in female mammals is randomly inactivated creating a Barr body33
6520879905Barr BodyThe inactivated X chromosome34
6520879906Genetic recombinationthe regrouping of genes in an offspring that results in a genetic makeup that is different from that of the parents35
6520879907linkage mapA genetic map based on the frequencies of recombination between markers during crossing over of homologous chromosomes.36
6520879908map unitin chromosome mapping, an increment of 1 percent in the frequency of crossing-over37
6520879909nondisjunctionError in meiosis in which homologous chromosomes fail to separate.38
6520879910aneuploidyA chromosomal aberration in which one or more chromosomes are present in extra copies or are deficient in number.39
6520879911polyploidyCondition in which an organism has extra full sets of chromosomes40
6520879912trisomy3 copies of a chromosome41
6520879913monosomyChromosomal abnormality consisting of the absence of one chromosome from the normal diploid number42
6520879914mutationan event that changes the nucleotide sequence in a gene, creating a novel sequence which may have no function or a new function43
6520879915point mutationGene mutation involving changes in one or a few nucleotides44
6520879916deletion(1) A deficiency in a chromosome resulting from the loss of a fragment through breakage. (2) A mutational loss of one or more nucleotide pairs from a gene.45
6520879917duplicationAn aberration in chromosome structure due to fusion with a fragment from a homologous chromosome, such that a portion of a chromosome is duplicated.46
6520879918inversion(genetics) a kind of mutation in which the order of the genes in a section of a chromosome is reversed47
6520879919translocationChange to a chromosome in which a fragment of one chromosome attaches to a nonhomologous chromosome48
6520879921Down SyndromeA condition of retardation and associated physical disorders caused by an extra copy of chromosome 21.49
6520879922Klinefelter syndromeA chromosomal disorder in which males have an extra X chromosome, making them XXY instead of XY.50
6520879923Turner Syndromea monosomic condition where a female has only 1 sex chromosome- the only known viable monosomy in humans51
6520879924true breedingIf an organism has a certain characteristic that is always passed on to its offspring, we say that this organism bred true with respect to that characteristic.52
6520879925linked genesGenes located close enough together on a chromosome that they tend to be inherited together.53
6520879926carrierA person whose genotype includes a gene that is not expressed in the phenotype.54

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