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AP Biology Molecular Genetics Flashcards

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6758413451nucleotidesa nitrogenous base, a sugar, and a phosphate group0
6758413452PurineA/G, 2 organic rings, 2X the size, 2 hydrogen bonds1
6758413453PyrimidineC/T, single ring, X size, 3 hydrogen bonds2
6758413455origins of replicationThe site where replication occurs where the two DNA strands are separated, opening up a replication "bubble".3
6758413456DNA polymeraseadds nucleotides to the 3' end of the growing DNA sequence. It needs a primer. It can only go in one direction and extend on an existing DNA molecule4
6758413457RNA PrimaseIn DNA replication, this enzyme adds temporary RNA nucleotides for DNA polymerase to work from and add nucleotides to5
6758413458replication forka Y-shaped region where new DNA strands are elongating that is located at the end of the replication bubble.6
6758413460Helicaseenzyme that untwist the double helix at the replication forks.7
6758413461Topoisomeraseenzyme that corrects "overwinding" ahead of replication forks by breaking, swiveling, and rejoining DNA strands8
6758413462leading strandthe template strand of DNA where replication happens continuously toward the replication fork because it is aligned properly9
6758413463lagging strandthe template strand of DNA where DNA polymerase must work in the direction away from the replication fork. New DNA is created in fragments10
6758413465Okazaki fragmentsThe fragments that compose the lagging strand. (The spaces between the fragments are later filled via DNA ligase to make a continuous DNA strand.)11
6758413466Chromatina complex of DNA and protein, is found in the nucleus of eukaryotic cells. DNA is spread out (not coiled)12
6758413473Transcriptionthe synthesis of RNA using information in DNA13
6758413474Translationthe synthesis of a polypeptide, using information in the mRNA14
6758413475Codona group of three nucleotides that code for an amino acid15
6758413476Ribosomesthe sites of translation16
6758413477primary transcriptinitial RNA transcript from any gene prior to processing17
6758413478central dogmathe concept that cells are governed by a cellular chain of command: DNA to RNA to protein18
6758413481promoterThe DNA sequence where RNA polymerase attaches to start transcription.19
6758413483The three stages of transcriptionInitiation, Elongation, Termination20
6758413484transcription initiation complexThe completed assembly of transcription factors and RNA polymerase II bound to a promoter21
6758413485Transcription factorsMolecules that mediate the binding of RNA polymerase and the initiation of transcription22
6758413487intronsThe noncoding regions of mRNA that get removed during RNA processing23
6758413491RNA splicingremoves introns and joins exons, creating an mRNA molecule with a continuous coding sequence24
6758413494tRNAstransfer amino acids to the growing polypeptide in a ribosome25
6758413495anticodonthree nucleotides in the tRNA that pairs with a complementary codon on mRNA26
6758413496P siteholds the tRNA that carries the growing polypeptide chain27
6758413520alternative RNA splicingdifferent mRNA molecules are produced from the same primary transcript, depending on which RNA segments are treated as exons and which as introns28
6758788583exonspart of the pre-mRNA that is not removed - they are joined together to make the mRNA29

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