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7300940571Dehydrationconnecting monomers together by the removal of water0
7300940572Hydrolysisdisassembling polymers by the addition of water1
7300940573Disaccharidesglucose + glucose = maltose / glucose + fructose = sucrose / glucose + galactose = lactose2
7300940574PolysaccharidesPlants: starch (energy) and cellulose (structure) Animals: glycogen (energy) and chitin (structure)3
7300940575*Lipidshydrophobic (very non-polar), consist of long hydrocarbon chains4
7300940576Fatsconsist of glycerol and 3 fatty acids, store long term energy, saturated = no double bond in hydrocarbon tails (no kink), unsaturated = double bond (kink)5
7300940577Phospholipidsconsist of phosphate head, glycerol, and 2 fatty acid tails, tail is hydrophobic, head is hydrophillic6
7300940578Protein structure and organizationcomposed of an amino group, a carboxyl group, hydrogen, and an R group, joined by peptide bonds and folded numerous times; 1) Primary (linear sequence) 2) Secondary (helix or pleat) 3) Tertiary 4) Quaternary (globular)7
7300940579Protein functions (8)1) enzymes 2) antibodies 3) storage proteins 4) transport proteins 5) hormones 6) receptor proteins 7) motor proteins 8) structural proteins8
7300940580*Nucleic AcidsDNA (A+T, G+C) carries genetic info, RNA (A+U, G+C) manufactures proteins9
7300940581Nuclear Envelopedouble membrane enclosing the nucleus (where genetic info is stored) perforated with pores, continuous with ER10
7300940582Chromatinuncondensed DNA that forms chromosomes during cell division11
7300940583Nucleolusnonmembranous structure involved in production of ribosomes, a nucleus has one or more of these12
7300940584Rough ERcovered in ribosomes, secretes and transports proteins produced by ribosomes13
7300940585Smooth ERmetabollic processes (synthesis of lipids, metabolism of carbs, detoxification of drugs and poisons)14
7300940586Golgistores, transports, and secretes cell products15
7300940587Cytoskeletonsupports cell, maintains its shape, aids in movement of cell products16
7300940588Centrosomes (2 centrioles)only in animal cells, microtubules used for cell division17
7300940589Lysosomesonly in animal cells, digestive organelles18
7300940590Flagellaonly in animal cells, cluster of microtubules for motility19
7300940591Extracellular Matrixonly in animal cells, made of proteins that provide support for cells and relay information for communication between the environment and the cell20
7300940592Central Vacuoleonly in plant cells, stores water and sugar, breaks down waste, and used as a mechanism for plant growth (when it swells)21
7300940593Prokaryotic vs. Eukaryoticnucleoid / nucleus; only ribosomes / complex membrane-bound organelles; both have same genetic coding, sugars, and amino acids22
7300940594Phospholipid Bilayertails of phospholipids are loosely packed and are in constant motion; membrane contains integral and peripheral proteins, cholestrol, and glycopreotins and glycolipids; cholesterol makes the membrane less permeable to water and other substances; non-polar and small polar molecules can pass through unadied23
7300940595Passive trasportmovement of molecules without requirement of energy: 1) diffusion 2) osmosis (across a membrane) 3) facilitated diffusion (helped by transport proteins)24
7300940596Active transportmovement of molecules that requires energy: 1) sodium-potassium pumps 2) exocytosis 3) endocytosis (phagocytosis, pinocytosis)25
7300940597Membrane Potentialvoltage across a membrane due to difference in positive and negative ions, electrons move from high to low concentration (ex. sodium-potassium pumps in neurons)26
7300940598Electrochemical Gradientdiffusion gradient resulting in combination of membrane potential and concentration gradient27
7300940599Hypertonicsolution with higher concentration of solutes, animal/plant cell in this solution would become shiveled/plasmolyzed28
7300940600Hypotonicsolution with lower concentration of solutes, animal/plant cell in this solution would lyse/become turgid29
7300940601Isotonicequal levels of solute concentration, plant cell in this solution would become flaccid30
7300940602When ΔG is negative......the reaction is exergonic (loss of free energy).31
7300940603When ΔG is positive......the reaction is endergonic (gain of free energy).32
7300940604*Enzymesproteins that are biological catalysts, lower the activation energy required to start a chemical reaction (reactants at unstable transition state) can be used over and over33
7300940605Substratethe substance that an enzyme acts upon34
7300940606Active Siteregion of enzyme that binds to the substrate35
7300940607Induced fitchange in the shape of an enzyme's active site induced by the substrate, helps to break down the substrate36
7300940608The higher the substrate concentration......the faster the reaction until the enzyme becomes saturated.37
7300940609Denaturationthe unraveling of an enzyme due to high temperatures or incompatible pH38
7300940610Cofactorsnonprotein molecules that are required for proper enzyme function, cofactors made of organic molecules are called coenzymes39
7300940611Enzyme inhibition may be irreversible if......the inhibitor attaches by covalent bonds (poisons, toxins)40
7300940612Competitive Inhibitorsresemble a substrate and block enzymes' active sites, can be overcome with higher concentration of substrate41
7300940613Noncompetitive Inhibitorsbind to a portion of the enzyme and change the shape of the active site so that it cannot match with substrates, used for regulating metabolic reactions42
7300940614Feedback Inhibitionthe product of a metabolic pathway switches off the enzyme that created it earlier in the process43
7300940615Oxidationloss of electrons (OIL)44
7300940616Reductiongain of electrons (RIG)45
7300940617Oxidative PhosphorylationATP synthesis powered by redox reactions that transfer electrons to oxygen46
7300940618Electron AcceptorsCellular respiration: NAD+ and FAD (to NADH and FADH2) Photosynthesis: NADP+ (to NADPH)47
7300940619GlycolysisInput: glucose, 2 ATP Output: 2 pyruvic acid, 4 ATP (net 2), 2 NADH48
7300940620Conversion Reaction before Kreb'sInput: 2 pyruvate Output: 2 acetyl (w/ CoA), 2 NADH, 2 CO249
7300940621Krebs CycleInput: 2 acetyl ➝ citric acid Output: 2 ATP, 6 NADH, 2 FADH2, 4 CO2 (after 2 turns of the cycle)50
7300940622Electron Transport ChainInput: NADH, FADH2, O2 (to accept e-) Output: 34-38 ATP, H2O51
7300940623Alcohol FermentationInput: glucose, 2 ATP, 2 NADH Output: 2 NAD+, 2 ethanol, 2 CO2, 4 ATP (net 2)52
7300940624Lactic Acid FermentationInput: glucose, 2 ATP, 2 NADH Output: 2 NAD+, 2 lactate, 4 ATP (net 2)53
7300940625Photosynthetic Equation54
7300940626Chloroplast structureExciting chlorophyll: chlorophyll in thylakoids absorb light, which excites electrons to produce potential energy55
7300940627Light ReactionsInput: H2O (2 e-), light energy, NADP+ Output: O2, ATP, NADPH56
7300940628Calvin CycleInput: 6 CO2 (fixed to RuBP by Rubisco), ATP, NADPH Output: 2 G3P = 1 glucose57
7300940629Watson and Crickbuilt the first accurate 3D DNA model58
7300940630Leading Strand vs. Lagging Strandworks toward replication fork / works away from replication fork; both always move in the 5' ➝ 3' direction59
7300940631Steps of DNA Replication1) helicase separates the DNA strands 2) SSB proteins prevent DNA from reanneling 3) primase creates RNA primer 4) DNA polymerase extends DNA strand from the primer 5) DNA polymerase I (RNase H) removes the primers 6) ligase joins the okazaki fragments of the lagging strand60
73009406323 types of RNA1) mRNA messenger 2) tRNA transfer amino acids (20 kinds) 3) rRNA ribosomes61
7300940633Transcription1) Initiation: promoter site (TATA) is recognized 2) Elongation: RNA polymerase adds ribonucleotides in the 5' ➝ 3' direction 3) Termination: RNA strand separates, RNA polymerase recognizes termination sequence (AAUAAA)62
7300940634RNA processing/splicingsplicesomes remove introns and put together exons, 5' cap and PolyA tail are added63
7300940635Codon vs. Anticodoncodon = nucleotide sequence on mRNA anticodon = nucleotide sequence on tRNA64
7300940636Translation1) Initiation: 5' cap attaches to ribosome which accepts an initiator tRNA at the P site (*AUG will always be 1st codon) 2) Elongation: codon/anticodon recognition and formation of peptide bond between A site amino acid and P site amino acid chain 3) translocation of the ribosome down the mRNA strand 4) Termination: ribosome will recognize stop codon and release the protein65
7300940637DNA mutationsbase-pair substitution; insertion/deletion; frameshift: 1) missense = different protein 2) nonsense = codes for a stop signal prematurely 3) silent = no harmful change66
7300940638Prokaryotic cell divisionbinary fission: splits in 2, exact copies, quick and efficient with few mutations, but reduces amount of genetic variation67
7300940639Somatic cell vs. Gameteany body cell except gametes / reproductive cells (sperm, egg)68
7300940640Interphase(90% of cell's life) G1: 1st growth, normal metabolic activity (goes into G0 phase if it is not ready for next phase); S: synthesis, DNA replication; G2: 2nd growth, prepares for mitosis69
7300940641Mitosis1) Prophase: chromatin condenses into chromosomes, nucleus disappears 2) Metaphase: chromosomes line up at equator, kinetechore microtubules attach 3) Anaphase: sister chromatids move to opposite poles of the cell 4) Telophase and Cytokinesis: daughter cells separate, nucleus reforms, chromosomes decondense70
7300940642Cyclin-dependent Kinases (Cdks)a regulatory protein that depends upon the presence of cyclin to complete its function, MPF is a Cdk that triggers a cell's passage into the M phase71
7300940643Meiosis I1) Prophase I: homologous chromosomes pair up and synapsis occurs, crossing over segments of the chromosomes (chiasma) to create more genetic variation 2) Metaphase I: homologous chromosomes line up at the equator 3) Anaphase: homologous chromosomes move to opposite poles of the cell. 4) Telophase I...72
7300940644Meiosis IIProphase II - Telophase II act exactly like mitosis except that the resultant number of daughter cells is 4 instead of 2, each with their own unique combination of genetic information73
73009406454 mechanisms that contribute to genetic variation1) Mutation 2) Independent Assortment: homologous chromosomes align randomly on one side of the equator or another 3) Crossing Over 4) Random Fertilization: a zygote can be any combination of a sperm and egg (64 trillion different combinations in humans)74
7300940646Testcrossbreed a homozygous recessive individual with an individual with a dominant phenotype but an unknown genotype to determine whether or not the individual is homozygous or heterozygous75
7300940647Dyhybrid heterozygous cross ratio9:3:3:176
7300940648Incomplete Dominanceheterozygous offspring have an intermediate phenotype of the parents, 1:2:1 ratio (ex. pink flower from red and white flowers)77
7300940649Codominanceboth alleles manifest themselves separately in an organism's phenotype (ex. roan cattle)78
7300940650Multiple allelesa trait controlled by two or more alleles (ex. blood type, eye color)79
7300940651Blood TypesA: A antigen, B antibody B: B antigen, A antibody AB: A and B antigen, no antibodies (universal recipient) O: no antigens, A and B antibodies (universal donor)80
7300940652Polygenic Inheritancethe additive effect of 2 or more independently assorted genes on phenotype (ex. human skin pigment)81
7300940653Linked genes phenotypic ratiotwo large numbers (wild and mutant) and two much smaller numbers (recombinant phenotypes)82
7300940654Genetic Map (Linkage/Cytological Map)ordered list of the genetic loci along a particular chromosome, recombinant frequencies can be used to construct it (smaller the percentage = closer together)83
7300940655X Inactivationin females during embryonic development, one of the two X chromosomes in a cell becomes inactive (Barr body) (ex. calico cats)84
7300940656Nondisjucntionhomologous chromosomes fail to separate during meiosis I or II85
7300940657Aneuploidyone or more chromosomes are present in extra copies or are deficient in number; Trisomic = 3 copies instead of 2, Monosomic = 1 copy instead of 286
7300940658Polyploidywhen there is a whole extra set of chromosomes (ex. oversized fruits); Triploidy = 3 sets, Tetraploidy = 4 sets87
73009406594 alterations to gene structure1) Deletion: removal of chromosomal segment 2) Duplication: repetition of a segment 3) Inversion: reversal of a segment within a chromosome 4) Translocation: movement of a segment from one chromosome to another, non-homologous one88
73009406603 stages in cell cummunication1) Reception: cell detects a signal via connection of a ligand to a receptor protein 2) Transduction: the receptor protein converts the signal to a form that can cause a chemical response 3) Response: transduced signal triggers a specific cellular response89
7300940661Types of cell signaling (4)synaptic, paracrine, hormonal90
7300940662Examples of cell signalingG-protein coupled receptor, ligand-gated ion channels, steroid hormones (dissolved across plasma membrane, intracellular receptor)91
7300940663Second Messengers and Phosphorylation cascadesecond messengers and kinases spread throughout a cell that help amplify a cellular signal by a series of phosphorylation reactions (addition of phosphate)92
7300940664Virus structurenonliving, can't rproduce on their own; Capsid: protein coat that encloses the viral genome; Envelope: membrane that surrounds some viral capsids; Phage: protein encapsulated virus that attacks bacteria93
7300940665Lytic Cycle1) virus attaches to host cell 2) phage DNA enters cell and the cell's DNA degrades (*restriction enzymes in bacteria could destroy them) 3) synthesis of viral genomes and proteins 4) assembly of phages within cell 5) release of viruses, destroys cell94
7300940666Lysogenic Cyclethe virus inserts its DNA into a host cell, and its DNA integrates with the DNA of the host, allows it to be replicated without being attacked for long periods of time before entering the lytic cycle95
7300940667RetrovirusRNA virus that transcribes its RNA into DNA to insert into host cells (ex. HIV)96
7300940668Provirusa viral genome that is permanently inserted into a host genome97
7300940669Viral Transductioncontributes to bacterial genetic variation98
7300940670Repressible Operontrp operon - usually on, can be repressed. Repressor protein produced in inactive shape99
7300940671Inducible Operonlac operon - usually off, can be turned on. Repressor protein produced in active shape.100
7300940672cAMP and CAP regulated Operonwhen CAP is inactive, transcription continues at a much less efficient rate even in the presence of lactose101
7300940673Histone Acetylationthe loosening of chromatin structure (euchromatin), promotes transcription102
7300940674Histone Methylationthe condensing of chromatin structure (heterochromatin), prevents transcription103
7300940675Transcription Factors and EnhancersRNA polymerase requires the assistance of transcription factor proteins and enhancers or activators to successfully transcribe RNA104
7300940676Epigenetic Inheritanceinheritance of traits not directly related to nucleotide sequence (ex. fat, sickly, yellow rats were fed a methylated diet, resulted in offspring that were normal-sized, healthy, and brown)105
73009406775 Evidences for Evolution1) Biogeography 2) Fossil Record 3) Comparative Anatomy 4) Comparative Embryology 5) Molecular Biology106
73009406784 conditions for Hardy-Weinberg Equilibrium (not evolving)1) very large population 2) isolation from other populations 3) no mutations 4) no natural selection107
7300940679Microevolution vs. Macroevolutionchange in the gene pool of a population over several generations / large scale changes in a population that leads to the evolution of a new species108
73009406804 causes of Microevolution1) genetic drift 2) gene flow 4) natural selection109
7300940681Genetic Driftrandom change in gene frequency of a small breeding population: 1) Founder Effect = small population of organisms colonizes a new area, 2) Bottleneck Effect = sudden decrease in population size due to disaster110
7300940682Gene Flowloss/addition of alleles from a population due to imigration/emigration111
7300940683Nonrandom Matingselection of mates for specific phenotypes: 1) Assortative Mating = when individuals select partners with simple phenotypic characters, 2) Inbreeding = more recessive traits likely to come together112
73009406843 Modes of Natural Selection1) Stabilizing: favors intermediate, 2) Directional: favors one extreme phenotype, 3) Diversifying: favors both extremes113
7300940685Heterozygote Advantageheterozygotes for a trait are more likely to survive (ex. carriers of sickle cell anemia are immune to malaria)114
7300940686Biological Species Conceptpopulation whose members can create viable, fertile offspring (Problems: doesn't apply to extinct animals or asexually reproducing organisms)115
7300940687Prezygotic Reproductive Barriers1) Habitat Isolation 2) Behavioral Isolation (differing behaviors for attracting mates) 3) Temporal Isolation (mate at different times) 4) Mechanical Isolation 5) Gametic Isolation (unable to fertilize egg)116
7300940688Postzygotic Reproductive Barriers1) Reduced Hybrid Viability (disruption in embryonic stage) 2) Reduced Hybrid Fertility 3) Hybrid Breakdown (F1 is fertile, F2 is sterile or weak)117
7300940689Allopatric Speciationwhen populations become geographically isolated from the rest of the species and has the potential to develop a new species (ex. Adaptive Radiation: many diversely adapted species from common ancestor, Darwin's finches)118
7300940690Sympatric Speciationmembers of a population develop gametic differences that prevent them from reproducing with the parental type (polyploidy, not as common)119
7300940691Punctuated Equilibrium vs. Gradualismevolution occurs in short spurts of rapid change / each new species will evolve gradually over long spans of time120
7300940692Convergent Evolutiondifferent organisms that occupy similar environments come to resemble one another (ex. dolphins and sharks)121
7300940693EndosymbiosisOrigin of mitochondria and chloroplasts. Evidence: They have their own DNA and ribosomes, double membrane structure, grow and reproduce on their own within the cell122
7300940694Phylogenyevolutionary history of a species or group of related species123
7300940695Taxonomic groups from broad to narrow (8)Domain, Kingdom, Phylum, Class, Order, Family, Genus, Species124
73009406963 mechanisms in which bacteria transfer genetic materials1) Transformation: prokaryote takes up DNA from its environment 2) Transduction: viruses transfer genes between prokaryotes 3) Conjugation: genes are directly transferred from one prokaryote to another over a temporary "mating bridge"125
7300940697Types of Symbiotic RelationshipsMutualism (+, +), Commensalism (+, 0), Parasitism, (+, -)126
7300940698Factors that influence Transpiration RateTemperature: higher temperature, faster rate; Humidity: higher humidity, slower rate; Sunlight: more sun, faster rate; Wind: more wind, faster rate127
7300940699Lines of Immune Defense1st Line) skin oil and sweat, mucous; 2nd Line) nonspecific phagocytes and cytotoxic immune cells; 3rd Line) specific immune system128
7300940700Primary and Secondary Immune Response129
7300940701Active vs. Passive Immunitydepends on the response of a person's own immune system (artificial = vaccines) / immunity passed from one organism to another130
7300940702B cells vs. T cells (maturation)mature in bone marrow / mature in thymus131
7300940703Humoral vs. Cell-Mediated Immune Responses132
7300940704Non-steroid hormone vs. Steroid hormonetravels in bloodstream, binds to receptor on cell surface / travels in bloodstream, binds to receptor inside the cell133
7300940705Endotherms vs. Ectothermswarmed by heat generated by metabolism (mammals, birds) / generate little metabolic heat, warmed by environment134
7300940706Nichea position/role taken by a kind of organism within its community135
7300940707Resource Partitioningdivision of environmental resources by coexisting species136
7300940708Per capita Growth Ratebirth - death / total population137
7300940709Exponential vs. Logistic Growthin logistic growth, carrying capacity will limit the population's size138
7300940710Density-dependent RegulationDensity-independent: natural disasters, human impact, etc.139
7300940711Keystone Speciesspecies that exerts strong control on community structure not by numerical might but by their pivotal ecological roles or niches140
7300940712Energy Pyramideach energy level receives only 10% of the pervious level's energy141
7300940713Gross Primary Production vs. Net Primary Productiontotal amount of energy from light converted to chemical energy to organic molecules / GPP - energy used by primary producers for "autotrophic respiration"142
7300940714Carbon CycleConnect photosynthesis (fixation) to cellular respiration (CO2 release)143
7300940715Plasmidsa small, circular, double-stranded DNA molecule that carries accessory genes separate from those of a bacterial chromosome144
7300940716Recombinant DNAa DNA vector made in vitro with segments from different sources145
7300940717Restriction Enzymean enzyme that recognizes and cuts DNA molecules at specific nucleotide sequences (restriction sites), can then be used to create recombinant DNA146
7300940718Gel Electrophoresisanalyzing fragments of DNA (RFLPs) by their length and charge to determine genetic fingerprints and other genetic information147

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