6654810361 | Dehydration | connecting monomers together by the removal of water | 0 | |
6654810362 | Hydrolysis | disassembling polymers by the addition of water | 1 | |
6654810363 | Disaccharides | glucose + glucose = maltose / glucose + fructose = sucrose / glucose + galactose = lactose | 2 | |
6654810364 | Polysaccharides | Plants: starch (energy) and cellulose (structure) Animals: glycogen (energy) and chitin (structure) | 3 | |
6654810365 | *Lipids | hydrophobic (very non-polar), consist of long hydrocarbon chains | 4 | |
6654810366 | Fats | consist of glycerol and 3 fatty acids, store long term energy, saturated = no double bond in hydrocarbon tails (no kink), unsaturated = double bond (kink) | 5 | |
6654810367 | Phospholipids | consist of phosphate head, glycerol, and 2 fatty acid tails, tail is hydrophobic, head is hydrophillic | 6 | |
6654810368 | Protein structure and organization | composed of an amino group, a carboxyl group, hydrogen, and an R group, joined by peptide bonds and folded numerous times; 1) Primary (linear sequence) 2) Secondary (helix or pleat) 3) Tertiary 4) Quaternary (globular) | 7 | |
6654810369 | Protein functions (8) | 1) enzymes 2) antibodies 3) storage proteins 4) transport proteins 5) hormones 6) receptor proteins 7) motor proteins 8) structural proteins | 8 | |
6654810370 | *Nucleic Acids | DNA (A+T, G+C) carries genetic info, RNA (A+U, G+C) manufactures proteins | 9 | |
6654810371 | Nuclear Envelope | double membrane enclosing the nucleus (where genetic info is stored) perforated with pores, continuous with ER | 10 | |
6654810372 | Chromatin | uncondensed DNA that forms chromosomes during cell division | 11 | |
6654810373 | Nucleolus | nonmembranous structure involved in production of ribosomes, a nucleus has one or more of these | 12 | |
6654810374 | Rough ER | covered in ribosomes, secretes and transports proteins produced by ribosomes | 13 | |
6654810375 | Smooth ER | metabollic processes (synthesis of lipids, metabolism of carbs, detoxification of drugs and poisons) | 14 | |
6654810376 | Golgi | stores, transports, and secretes cell products | 15 | |
6654810377 | Cytoskeleton | supports cell, maintains its shape, aids in movement of cell products | 16 | |
6654810378 | Centrosomes (2 centrioles) | only in animal cells, microtubules used for cell division | 17 | |
6654810379 | Lysosomes | only in animal cells, digestive organelles | 18 | |
6654810380 | Flagella | only in animal cells, cluster of microtubules for motility | 19 | |
6654810381 | Extracellular Matrix | only in animal cells, made of proteins that provide support for cells and relay information for communication between the environment and the cell | 20 | |
6654810382 | Central Vacuole | only in plant cells, stores water and sugar, breaks down waste, and used as a mechanism for plant growth (when it swells) | 21 | |
6654810383 | Prokaryotic vs. Eukaryotic | nucleoid / nucleus; only ribosomes / complex membrane-bound organelles; both have same genetic coding, sugars, and amino acids | 22 | |
6654810384 | Phospholipid Bilayer | tails of phospholipids are loosely packed and are in constant motion; membrane contains integral and peripheral proteins, cholestrol, and glycopreotins and glycolipids; cholesterol makes the membrane less permeable to water and other substances; non-polar and small polar molecules can pass through unadied | 23 | |
6654810385 | Passive trasport | movement of molecules without requirement of energy: 1) diffusion 2) osmosis (across a membrane) 3) facilitated diffusion (helped by transport proteins) | 24 | |
6654810386 | Active transport | movement of molecules that requires energy: 1) sodium-potassium pumps 2) exocytosis 3) endocytosis (phagocytosis, pinocytosis) | 25 | |
6654810387 | Membrane Potential | voltage across a membrane due to difference in positive and negative ions, electrons move from high to low concentration (ex. sodium-potassium pumps in neurons) | 26 | |
6654810388 | Electrochemical Gradient | diffusion gradient resulting in combination of membrane potential and concentration gradient | 27 | |
6654810389 | Hypertonic | solution with higher concentration of solutes, animal/plant cell in this solution would become shiveled/plasmolyzed | 28 | |
6654810390 | Hypotonic | solution with lower concentration of solutes, animal/plant cell in this solution would lyse/become turgid | 29 | |
6654810391 | Isotonic | equal levels of solute concentration, plant cell in this solution would become flaccid | 30 | |
6654810392 | When ΔG is negative... | ...the reaction is exergonic (loss of free energy). | 31 | |
6654810393 | When ΔG is positive... | ...the reaction is endergonic (gain of free energy). | 32 | |
6654810394 | *Enzymes | proteins that are biological catalysts, lower the activation energy required to start a chemical reaction (reactants at unstable transition state) can be used over and over | 33 | |
6654810395 | Substrate | the substance that an enzyme acts upon | 34 | |
6654810396 | Active Site | region of enzyme that binds to the substrate | 35 | |
6654810397 | Induced fit | change in the shape of an enzyme's active site induced by the substrate, helps to break down the substrate | 36 | |
6654810398 | The higher the substrate concentration... | ...the faster the reaction until the enzyme becomes saturated. | 37 | |
6654810399 | Denaturation | the unraveling of an enzyme due to high temperatures or incompatible pH | 38 | |
6654810400 | Cofactors | nonprotein molecules that are required for proper enzyme function, cofactors made of organic molecules are called coenzymes | 39 | |
6654810401 | Enzyme inhibition may be irreversible if... | ...the inhibitor attaches by covalent bonds (poisons, toxins) | 40 | |
6654810402 | Competitive Inhibitors | resemble a substrate and block enzymes' active sites, can be overcome with higher concentration of substrate | 41 | |
6654810403 | Noncompetitive Inhibitors | bind to a portion of the enzyme and change the shape of the active site so that it cannot match with substrates, used for regulating metabolic reactions | 42 | |
6654810404 | Feedback Inhibition | the product of a metabolic pathway switches off the enzyme that created it earlier in the process | 43 | |
6654810405 | Oxidation | loss of electrons (OIL) | 44 | |
6654810406 | Reduction | gain of electrons (RIG) | 45 | |
6654810407 | Oxidative Phosphorylation | ATP synthesis powered by redox reactions that transfer electrons to oxygen | 46 | |
6654810408 | Electron Acceptors | Cellular respiration: NAD+ and FAD (to NADH and FADH2) Photosynthesis: NADP+ (to NADPH) | 47 | |
6654810409 | Glycolysis | Input: glucose, 2 ATP Output: 2 pyruvic acid, 4 ATP (net 2), 2 NADH | 48 | |
6654810410 | Conversion Reaction before Kreb's | Input: 2 pyruvate Output: 2 acetyl (w/ CoA), 2 NADH, 2 CO2 | 49 | |
6654810411 | Krebs Cycle | Input: 2 acetyl ➝ citric acid Output: 2 ATP, 6 NADH, 2 FADH2, 4 CO2 (after 2 turns of the cycle) | 50 | |
6654810412 | Electron Transport Chain | Input: NADH, FADH2, O2 (to accept e-) Output: 34-38 ATP, H2O | 51 | |
6654810413 | Alcohol Fermentation | Input: glucose, 2 ATP, 2 NADH Output: 2 NAD+, 2 ethanol, 2 CO2, 4 ATP (net 2) | 52 | |
6654810414 | Lactic Acid Fermentation | Input: glucose, 2 ATP, 2 NADH Output: 2 NAD+, 2 lactate, 4 ATP (net 2) | 53 | |
6654810415 | Photosynthetic Equation | 54 | ||
6654810416 | Chloroplast structure | Exciting chlorophyll: chlorophyll in thylakoids absorb light, which excites electrons to produce potential energy | 55 | |
6654810417 | Light Reactions | Input: H2O (2 e-), light energy, NADP+ Output: O2, ATP, NADPH | 56 | |
6654810418 | Calvin Cycle | Input: 6 CO2 (fixed to RuBP by Rubisco), ATP, NADPH Output: 2 G3P = 1 glucose | 57 | |
6654810419 | Watson and Crick | built the first accurate 3D DNA model | 58 | |
6654810420 | Leading Strand vs. Lagging Strand | works toward replication fork / works away from replication fork; both always move in the 5' ➝ 3' direction | 59 | |
6654810421 | Steps of DNA Replication | 1) helicase separates the DNA strands 2) SSB proteins prevent DNA from reanneling 3) primase creates RNA primer 4) DNA polymerase extends DNA strand from the primer 5) DNA polymerase I (RNase H) removes the primers 6) ligase joins the okazaki fragments of the lagging strand | 60 | |
6654810422 | 3 types of RNA | 1) mRNA messenger 2) tRNA transfer amino acids (20 kinds) 3) rRNA ribosomes | 61 | |
6654810423 | Transcription | 1) Initiation: promoter site (TATA) is recognized 2) Elongation: RNA polymerase adds ribonucleotides in the 5' ➝ 3' direction 3) Termination: RNA strand separates, RNA polymerase recognizes termination sequence (AAUAAA) | 62 | |
6654810424 | RNA processing/splicing | splicesomes remove introns and put together exons, 5' cap and PolyA tail are added | 63 | |
6654810425 | Codon vs. Anticodon | codon = nucleotide sequence on mRNA anticodon = nucleotide sequence on tRNA | 64 | |
6654810426 | Translation | 1) Initiation: 5' cap attaches to ribosome which accepts an initiator tRNA at the P site (*AUG will always be 1st codon) 2) Elongation: codon/anticodon recognition and formation of peptide bond between A site amino acid and P site amino acid chain 3) translocation of the ribosome down the mRNA strand 4) Termination: ribosome will recognize stop codon and release the protein | 65 | |
6654810427 | DNA mutations | base-pair substitution; insertion/deletion; frameshift: 1) missense = different protein 2) nonsense = codes for a stop signal prematurely 3) silent = no harmful change | 66 | |
6654810428 | Prokaryotic cell division | binary fission: splits in 2, exact copies, quick and efficient with few mutations, but reduces amount of genetic variation | 67 | |
6654810429 | Somatic cell vs. Gamete | any body cell except gametes / reproductive cells (sperm, egg) | 68 | |
6654810430 | Interphase | (90% of cell's life) G1: 1st growth, normal metabolic activity (goes into G0 phase if it is not ready for next phase); S: synthesis, DNA replication; G2: 2nd growth, prepares for mitosis | 69 | |
6654810431 | Mitosis | 1) Prophase: chromatin condenses into chromosomes, nucleus disappears 2) Metaphase: chromosomes line up at equator, kinetechore microtubules attach 3) Anaphase: sister chromatids move to opposite poles of the cell 4) Telophase and Cytokinesis: daughter cells separate, nucleus reforms, chromosomes decondense | 70 | |
6654810432 | Cyclin-dependent Kinases (Cdks) | a regulatory protein that depends upon the presence of cyclin to complete its function, MPF is a Cdk that triggers a cell's passage into the M phase | 71 | |
6654810433 | Meiosis I | 1) Prophase I: homologous chromosomes pair up and synapsis occurs, crossing over segments of the chromosomes (chiasma) to create more genetic variation 2) Metaphase I: homologous chromosomes line up at the equator 3) Anaphase: homologous chromosomes move to opposite poles of the cell. 4) Telophase I... | 72 | |
6654810434 | Meiosis II | Prophase II - Telophase II act exactly like mitosis except that the resultant number of daughter cells is 4 instead of 2, each with their own unique combination of genetic information | 73 | |
6654810435 | 4 mechanisms that contribute to genetic variation | 1) Mutation 2) Independent Assortment: homologous chromosomes align randomly on one side of the equator or another 3) Crossing Over 4) Random Fertilization: a zygote can be any combination of a sperm and egg (64 trillion different combinations in humans) | 74 | |
6654810436 | Testcross | breed a homozygous recessive individual with an individual with a dominant phenotype but an unknown genotype to determine whether or not the individual is homozygous or heterozygous | 75 | |
6654810437 | Dyhybrid heterozygous cross ratio | 9:3:3:1 | 76 | |
6654810438 | Incomplete Dominance | heterozygous offspring have an intermediate phenotype of the parents, 1:2:1 ratio (ex. pink flower from red and white flowers) | 77 | |
6654810439 | Codominance | both alleles manifest themselves separately in an organism's phenotype (ex. roan cattle) | 78 | |
6654810440 | Multiple alleles | a trait controlled by two or more alleles (ex. blood type, eye color) | 79 | |
6654810441 | Blood Types | A: A antigen, B antibody B: B antigen, A antibody AB: A and B antigen, no antibodies (universal recipient) O: no antigens, A and B antibodies (universal donor) | 80 | |
6654810442 | Polygenic Inheritance | the additive effect of 2 or more independently assorted genes on phenotype (ex. human skin pigment) | 81 | |
6654810443 | Linked genes phenotypic ratio | two large numbers (wild and mutant) and two much smaller numbers (recombinant phenotypes) | 82 | |
6654810444 | Genetic Map (Linkage/Cytological Map) | ordered list of the genetic loci along a particular chromosome, recombinant frequencies can be used to construct it (smaller the percentage = closer together) | 83 | |
6654810445 | X Inactivation | in females during embryonic development, one of the two X chromosomes in a cell becomes inactive (Barr body) (ex. calico cats) | 84 | |
6654810446 | Nondisjucntion | homologous chromosomes fail to separate during meiosis I or II | 85 | |
6654810447 | Aneuploidy | one or more chromosomes are present in extra copies or are deficient in number; Trisomic = 3 copies instead of 2, Monosomic = 1 copy instead of 2 | 86 | |
6654810448 | Polyploidy | when there is a whole extra set of chromosomes (ex. oversized fruits); Triploidy = 3 sets, Tetraploidy = 4 sets | 87 | |
6654810449 | 4 alterations to gene structure | 1) Deletion: removal of chromosomal segment 2) Duplication: repetition of a segment 3) Inversion: reversal of a segment within a chromosome 4) Translocation: movement of a segment from one chromosome to another, non-homologous one | 88 | |
6654810450 | 3 stages in cell cummunication | 1) Reception: cell detects a signal via connection of a ligand to a receptor protein 2) Transduction: the receptor protein converts the signal to a form that can cause a chemical response 3) Response: transduced signal triggers a specific cellular response | 89 | |
6654810451 | Types of cell signaling (4) | synaptic, paracrine, hormonal | 90 | |
6654810452 | Examples of cell signaling | G-protein coupled receptor, ligand-gated ion channels, steroid hormones (dissolved across plasma membrane, intracellular receptor) | 91 | |
6654810453 | Second Messengers and Phosphorylation cascade | second messengers and kinases spread throughout a cell that help amplify a cellular signal by a series of phosphorylation reactions (addition of phosphate) | 92 | |
6654810454 | Virus structure | nonliving, can't rproduce on their own; Capsid: protein coat that encloses the viral genome; Envelope: membrane that surrounds some viral capsids; Phage: protein encapsulated virus that attacks bacteria | 93 | |
6654810455 | Lytic Cycle | 1) virus attaches to host cell 2) phage DNA enters cell and the cell's DNA degrades (*restriction enzymes in bacteria could destroy them) 3) synthesis of viral genomes and proteins 4) assembly of phages within cell 5) release of viruses, destroys cell | 94 | |
6654810456 | Lysogenic Cycle | the virus inserts its DNA into a host cell, and its DNA integrates with the DNA of the host, allows it to be replicated without being attacked for long periods of time before entering the lytic cycle | 95 | |
6654810457 | Retrovirus | RNA virus that transcribes its RNA into DNA to insert into host cells (ex. HIV) | 96 | |
6654810458 | Provirus | a viral genome that is permanently inserted into a host genome | 97 | |
6654810459 | Viral Transduction | contributes to bacterial genetic variation | 98 | |
6654810460 | Repressible Operon | trp operon - usually on, can be repressed. Repressor protein produced in inactive shape | 99 | |
6654810461 | Inducible Operon | lac operon - usually off, can be turned on. Repressor protein produced in active shape. | 100 | |
6654810462 | cAMP and CAP regulated Operon | when CAP is inactive, transcription continues at a much less efficient rate even in the presence of lactose | 101 | |
6654810463 | Histone Acetylation | the loosening of chromatin structure (euchromatin), promotes transcription | 102 | |
6654810464 | Histone Methylation | the condensing of chromatin structure (heterochromatin), prevents transcription | 103 | |
6654810465 | Transcription Factors and Enhancers | RNA polymerase requires the assistance of transcription factor proteins and enhancers or activators to successfully transcribe RNA | 104 | |
6654810466 | Epigenetic Inheritance | inheritance of traits not directly related to nucleotide sequence (ex. fat, sickly, yellow rats were fed a methylated diet, resulted in offspring that were normal-sized, healthy, and brown) | 105 | |
6654810467 | 5 Evidences for Evolution | 1) Biogeography 2) Fossil Record 3) Comparative Anatomy 4) Comparative Embryology 5) Molecular Biology | 106 | |
6654810468 | 4 conditions for Hardy-Weinberg Equilibrium (not evolving) | 1) very large population 2) isolation from other populations 3) no mutations 4) no natural selection | 107 | |
6654810469 | Microevolution vs. Macroevolution | change in the gene pool of a population over several generations / large scale changes in a population that leads to the evolution of a new species | 108 | |
6654810470 | 4 causes of Microevolution | 1) genetic drift 2) gene flow 4) natural selection | 109 | |
6654810471 | Genetic Drift | random change in gene frequency of a small breeding population: 1) Founder Effect = small population of organisms colonizes a new area, 2) Bottleneck Effect = sudden decrease in population size due to disaster | 110 | |
6654810472 | Gene Flow | loss/addition of alleles from a population due to imigration/emigration | 111 | |
6654810473 | Nonrandom Mating | selection of mates for specific phenotypes: 1) Assortative Mating = when individuals select partners with simple phenotypic characters, 2) Inbreeding = more recessive traits likely to come together | 112 | |
6654810474 | 3 Modes of Natural Selection | 1) Stabilizing: favors intermediate, 2) Directional: favors one extreme phenotype, 3) Diversifying: favors both extremes | 113 | |
6654810475 | Heterozygote Advantage | heterozygotes for a trait are more likely to survive (ex. carriers of sickle cell anemia are immune to malaria) | 114 | |
6654810476 | Biological Species Concept | population whose members can create viable, fertile offspring (Problems: doesn't apply to extinct animals or asexually reproducing organisms) | 115 | |
6654810477 | Prezygotic Reproductive Barriers | 1) Habitat Isolation 2) Behavioral Isolation (differing behaviors for attracting mates) 3) Temporal Isolation (mate at different times) 4) Mechanical Isolation 5) Gametic Isolation (unable to fertilize egg) | 116 | |
6654810478 | Postzygotic Reproductive Barriers | 1) Reduced Hybrid Viability (disruption in embryonic stage) 2) Reduced Hybrid Fertility 3) Hybrid Breakdown (F1 is fertile, F2 is sterile or weak) | 117 | |
6654810479 | Allopatric Speciation | when populations become geographically isolated from the rest of the species and has the potential to develop a new species (ex. Adaptive Radiation: many diversely adapted species from common ancestor, Darwin's finches) | 118 | |
6654810480 | Sympatric Speciation | members of a population develop gametic differences that prevent them from reproducing with the parental type (polyploidy, not as common) | 119 | |
6654810481 | Punctuated Equilibrium vs. Gradualism | evolution occurs in short spurts of rapid change / each new species will evolve gradually over long spans of time | 120 | |
6654810482 | Convergent Evolution | different organisms that occupy similar environments come to resemble one another (ex. dolphins and sharks) | 121 | |
6654810483 | Endosymbiosis | Origin of mitochondria and chloroplasts. Evidence: They have their own DNA and ribosomes, double membrane structure, grow and reproduce on their own within the cell | 122 | |
6654810484 | Phylogeny | evolutionary history of a species or group of related species | 123 | |
6654810485 | Taxonomic groups from broad to narrow (8) | Domain, Kingdom, Phylum, Class, Order, Family, Genus, Species | 124 | |
6654810486 | 3 mechanisms in which bacteria transfer genetic materials | 1) Transformation: prokaryote takes up DNA from its environment 2) Transduction: viruses transfer genes between prokaryotes 3) Conjugation: genes are directly transferred from one prokaryote to another over a temporary "mating bridge" | 125 | |
6654810487 | Types of Symbiotic Relationships | Mutualism (+, +), Commensalism (+, 0), Parasitism, (+, -) | 126 | |
6654810488 | Factors that influence Transpiration Rate | Temperature: higher temperature, faster rate; Humidity: higher humidity, slower rate; Sunlight: more sun, faster rate; Wind: more wind, faster rate | 127 | |
6654810489 | Lines of Immune Defense | 1st Line) skin oil and sweat, mucous; 2nd Line) nonspecific phagocytes and cytotoxic immune cells; 3rd Line) specific immune system | 128 | |
6654810490 | Primary and Secondary Immune Response | 129 | ||
6654810491 | Active vs. Passive Immunity | depends on the response of a person's own immune system (artificial = vaccines) / immunity passed from one organism to another | 130 | |
6654810492 | B cells vs. T cells (maturation) | mature in bone marrow / mature in thymus | 131 | |
6654810493 | Humoral vs. Cell-Mediated Immune Responses | 132 | ||
6654810494 | Non-steroid hormone vs. Steroid hormone | travels in bloodstream, binds to receptor on cell surface / travels in bloodstream, binds to receptor inside the cell | 133 | |
6654810495 | Endotherms vs. Ectotherms | warmed by heat generated by metabolism (mammals, birds) / generate little metabolic heat, warmed by environment | 134 | |
6654810496 | Niche | a position/role taken by a kind of organism within its community | 135 | |
6654810497 | Resource Partitioning | division of environmental resources by coexisting species | 136 | |
6654810498 | Per capita Growth Rate | birth - death / total population | 137 | |
6654810499 | Exponential vs. Logistic Growth | in logistic growth, carrying capacity will limit the population's size | 138 | |
6654810500 | Density-dependent Regulation | Density-independent: natural disasters, human impact, etc. | 139 | |
6654810501 | Keystone Species | species that exerts strong control on community structure not by numerical might but by their pivotal ecological roles or niches | 140 | |
6654810502 | Energy Pyramid | each energy level receives only 10% of the pervious level's energy | 141 | |
6654810503 | Gross Primary Production vs. Net Primary Production | total amount of energy from light converted to chemical energy to organic molecules / GPP - energy used by primary producers for "autotrophic respiration" | 142 | |
6654810504 | Carbon Cycle | Connect photosynthesis (fixation) to cellular respiration (CO2 release) | 143 | |
6654810505 | Plasmids | a small, circular, double-stranded DNA molecule that carries accessory genes separate from those of a bacterial chromosome | 144 | |
6654810506 | Recombinant DNA | a DNA vector made in vitro with segments from different sources | 145 | |
6654810507 | Restriction Enzyme | an enzyme that recognizes and cuts DNA molecules at specific nucleotide sequences (restriction sites), can then be used to create recombinant DNA | 146 | |
6654810508 | Gel Electrophoresis | analyzing fragments of DNA (RFLPs) by their length and charge to determine genetic fingerprints and other genetic information | 147 |
AP Biology Review Flashcards
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