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6679902450Dehydration Synthesisconnecting monomers together by the removal of water0
6679902451Hydrolysisdisassembling polymers by the addition of water1
6679902452Disaccharidesglucose + glucose = maltose / glucose + fructose = sucrose / glucose + galactose = lactose2
6679902453PolysaccharidesPlants: starch (energy) and cellulose (structure) Animals: glycogen (energy) and chitin (structure)3
6679902454Lipidshydrophobic (very non-polar), consist of long hydrocarbon chains4
6679902455Fatsconsist of glycerol and 3 fatty acids, store long term energy, saturated = no double bond in hydrocarbon tails (no kink), unsaturated = double bond (kink)5
6679902456Phospholipidsconsist of phosphate head, glycerol, and 2 fatty acid tails, tail is hydrophobic, head is hydrophillic6
6679902457Protein structure and organizationcomposed of an amino group, a carboxyl group, hydrogen, and an R group, joined by peptide bonds and folded numerous times; 1) Primary (linear sequence) 2) Secondary (helix or pleat) 3) Tertiary 4) Quaternary (globular)7
6679902458Protein functions (8)1) enzymes 2) antibodies 3) storage proteins 4) transport proteins 5) hormones 6) receptor proteins 7) motor proteins 8) structural proteins8
6679902459Nucleic AcidsDNA (A+T, G+C) carries genetic info, RNA (A+U, G+C) manufactures proteins9
6679902460Nuclear Envelopedouble membrane enclosing the nucleus (where genetic info is stored) perforated with pores, continuous with ER10
6679902461Chromatinuncondensed DNA that forms chromosomes during cell division11
6679902462Nucleolusnonmembranous structure involved in production of ribosomes, a nucleus has one or more of these12
6679902463Rough ERcovered in ribosomes, secretes and transports proteins produced by ribosomes13
6679902464Smooth ERmetabollic processes (synthesis of lipids, metabolism of carbs, detoxification of drugs and poisons)14
6679902465Golgipackages, stores, transports, and secretes cell products15
6679902466Cytoskeletonsupports cell, maintains its shape, aids in movement of cell products16
6679902467Centrosomes (2 centrioles)only in animal cells, microtubules used for cell division17
6679902468Lysosomesonly in animal cells, digestive organelles18
6679902469Flagellaonly in animal cells, cluster of microtubules for motility19
6679902470Extracellular Matrixonly in animal cells, made of proteins that provide support for cells and relay information for communication between the environment and the cell20
6679902471Central Vacuoleonly in plant cells, stores water and sugar, breaks down waste, and used as a mechanism for plant growth (when it swells)21
6679902472Prokaryoticone of two major cell types - no membrane bound organelles22
6679902473Phospholipid Bilayertails of phospholipids are loosely packed and are in constant motion; membrane contains integral and peripheral proteins, cholestrol, and glycopreotins and glycolipids; cholesterol makes the membrane less permeable to water and other substances; non-polar and small polar molecules can pass through unadied23
6679902474Passive trasportmovement of molecules without requirement of energy: 1) diffusion 2) osmosis (across a membrane) 3) facilitated diffusion (helped by transport proteins)24
6679902475Active transportmovement of molecules that requires energy: 1) sodium-potassium pumps 2) exocytosis 3) endocytosis (phagocytosis, pinocytosis)25
6679902476Membrane Potentialvoltage across a membrane due to difference in positive and negative ions, electrons move from high to low concentration (ex. sodium-potassium pumps in neurons)26
6679902477Electrochemical Gradientdiffusion gradient resulting in combination of membrane potential and concentration gradient27
6679902478Hypertonicsolution with higher concentration of solutes, animal/plant cell in this solution would become shiveled/plasmolyzed28
6679902479Hypotonicsolution with lower concentration of solutes, animal/plant cell in this solution would lyse/become turgid29
6679902480Isotonicequal levels of solute concentration, plant cell in this solution would become flaccid30
6679902481When ΔG is negative......the reaction is exergonic (loss of free energy).31
6679902482When ΔG is positive......the reaction is endergonic (gain of free energy).32
6679902483*Enzymesproteins that are biological catalysts, lower the activation energy required to start a chemical reaction (reactants at unstable transition state) can be used over and over33
6679902484Substratethe substance that an enzyme acts upon34
6679902485Active Siteregion of enzyme that binds to the substrate35
6679902486Induced fitchange in the shape of an enzyme's active site induced by the substrate, helps to break down the substrate36
6679902487The higher the substrate concentration......the faster the reaction until the enzyme becomes saturated.37
6679902488Denaturationthe unraveling of an enzyme due to high temperatures or incompatible pH38
6679902489Cofactorsnonprotein molecules that are required for proper enzyme function, cofactors made of organic molecules are called coenzymes39
6679902490Enzyme inhibition may be irreversible if......the inhibitor attaches by covalent bonds (poisons, toxins)40
6679902491Competitive Inhibitorsresemble a substrate and block enzymes' active sites, can be overcome with higher concentration of substrate41
6679902492Noncompetitive Inhibitorsbind to a portion of the enzyme and change the shape of the active site so that it cannot match with substrates, used for regulating metabolic reactions42
6679902493Feedback Inhibitionthe product of a metabolic pathway switches off the enzyme that created it earlier in the process43
6679902494Oxidationloss of electrons (OIL)44
6679902495Reductiongain of electrons (RIG)45
6679902496Oxidative PhosphorylationATP synthesis powered by redox reactions that transfer electrons to oxygen46
6679902497Electron AcceptorsCellular respiration: NAD+ and FAD (to NADH and FADH2) Photosynthesis: NADP+ (to NADPH)47
6679902498GlycolysisInput: glucose, 2 ATP Output: 2 pyruvic acid, 4 ATP (net 2), 2 NADH48
6679902499Conversion Reaction before Kreb'sInput: 2 pyruvate Output: 2 acetyl (w/ CoA), 2 NADH, 2 CO249
6679902500Krebs CycleInput: 2 acetyl ➝ citric acid Output: 2 ATP, 6 NADH, 2 FADH2, 4 CO2 (after 2 turns of the cycle)50
6679902501Electron Transport ChainInput: NADH, FADH2, O2 (to accept e-) Output: 34-38 ATP, H2O51
6679902502Alcohol FermentationInput: glucose, 2 ATP, 2 NADH Output: 2 NAD+, 2 ethanol, 2 CO2, 4 ATP (net 2)52
6679902503Lactic Acid FermentationInput: glucose, 2 ATP, 2 NADH Output: 2 NAD+, 2 lactate, 4 ATP (net 2)53
6679902504Photosynthetic Equation54
6679902505Chloroplast structureExciting chlorophyll: chlorophyll in thylakoids absorb light, which excites electrons to produce potential energy55
6679902506Light ReactionsInput: H2O (2 e-), light energy, NADP+ Output: O2, ATP, NADPH56
6679902507Calvin CycleInput: 6 CO2 (fixed to RuBP by Rubisco), ATP, NADPH Output: 2 G3P = 1 glucose57
6679902508Watson and Crickbuilt the first accurate 3D DNA model58
6679902509Leading Strand vs. Lagging Strandworks toward replication fork / works away from replication fork; both always move in the 5' ➝ 3' direction59
6679902510Steps of DNA Replication1) helicase separates the DNA strands 2) SSB proteins prevent DNA from reanneling 3) primase creates RNA primer 4) DNA polymerase extends DNA strand from the primer 5) DNA polymerase I (RNase H) removes the primers 6) ligase joins the okazaki fragments of the lagging strand60
66799025113 types of RNA1) mRNA messenger 2) tRNA transfer amino acids (20 kinds) 3) rRNA ribosomes61
6679902512Transcription1) Initiation: promoter site (TATA) is recognized 2) Elongation: RNA polymerase adds ribonucleotides in the 5' ➝ 3' direction 3) Termination: RNA strand separates, RNA polymerase recognizes termination sequence (AAUAAA)62
6679902513RNA processing/splicingsplicesomes remove introns and put together exons, 5' cap and PolyA tail are added63
6679902514Codon vs. Anticodoncodon = nucleotide sequence on mRNA anticodon = nucleotide sequence on tRNA64
6679902515Translation1) Initiation: 5' cap attaches to ribosome which accepts an initiator tRNA at the P site (*AUG will always be 1st codon) 2) Elongation: codon/anticodon recognition and formation of peptide bond between A site amino acid and P site amino acid chain 3) translocation of the ribosome down the mRNA strand 4) Termination: ribosome will recognize stop codon and release the protein65
6679902516DNA mutationsbase-pair substitution; insertion/deletion; frameshift: 1) missense = different protein 2) nonsense = codes for a stop signal prematurely 3) silent = no harmful change66
6679902517Prokaryotic cell divisionbinary fission: splits in 2, exact copies, quick and efficient with few mutations, but reduces amount of genetic variation67
6679902518Somatic cell vs. Gameteany body cell except gametes / reproductive cells (sperm, egg)68
6679902519Interphase(90% of cell's life) G1: 1st growth, normal metabolic activity (goes into G0 phase if it is not ready for next phase); S: synthesis, DNA replication; G2: 2nd growth, prepares for mitosis69
6679902520Mitosis1) Prophase: chromatin condenses into chromosomes, nucleus disappears 2) Metaphase: chromosomes line up at equator, kinetechore microtubules attach 3) Anaphase: sister chromatids move to opposite poles of the cell 4) Telophase and Cytokinesis: daughter cells separate, nucleus reforms, chromosomes decondense70
6679902521Cyclin-dependent Kinases (Cdks)a regulatory protein that depends upon the presence of cyclin to complete its function, MPF is a Cdk that triggers a cell's passage into the M phase71
6679902522Meiosis I1) Prophase I: homologous chromosomes pair up and synapsis occurs, crossing over segments of the chromosomes (chiasma) to create more genetic variation 2) Metaphase I: homologous chromosomes line up at the equator 3) Anaphase: homologous chromosomes move to opposite poles of the cell. 4) Telophase I...72
6679902523Meiosis IIProphase II - Telophase II act exactly like mitosis except that the resultant number of daughter cells is 4 instead of 2, each with their own unique combination of genetic information73
66799025244 mechanisms that contribute to genetic variation1) Mutation 2) Independent Assortment: homologous chromosomes align randomly on one side of the equator or another 3) Crossing Over 4) Random Fertilization: a zygote can be any combination of a sperm and egg (64 trillion different combinations in humans)74
6679902525Testcrossbreed a homozygous recessive individual with an individual with a dominant phenotype but an unknown genotype to determine whether or not the individual is homozygous or heterozygous75
6679902526Dyhybrid heterozygous cross ratio9:3:3:176
6679902527Incomplete Dominanceheterozygous offspring have an intermediate phenotype of the parents, 1:2:1 ratio (ex. pink flower from red and white flowers)77
6679902528Codominanceboth alleles manifest themselves separately in an organism's phenotype (ex. roan cattle)78
6679902529Multiple allelesa trait controlled by two or more alleles (ex. blood type, eye color)79
6679902530Blood TypesA: A antigen, B antibody B: B antigen, A antibody AB: A and B antigen, no antibodies (universal recipient) O: no antigens, A and B antibodies (universal donor)80
6679902531Polygenic Inheritancethe additive effect of 2 or more independently assorted genes on phenotype (ex. human skin pigment)81
6679902532Linked genes phenotypic ratiotwo large numbers (wild and mutant) and two much smaller numbers (recombinant phenotypes)82
6679902533Genetic Map (Linkage/Cytological Map)ordered list of the genetic loci along a particular chromosome, recombinant frequencies can be used to construct it (smaller the percentage = closer together)83
6679902534X Inactivationin females during embryonic development, one of the two X chromosomes in a cell becomes inactive (Barr body) (ex. calico cats)84
6679902535Nondisjucntionhomologous chromosomes fail to separate during meiosis I or II85
6679902536Aneuploidyone or more chromosomes are present in extra copies or are deficient in number; Trisomic = 3 copies instead of 2, Monosomic = 1 copy instead of 286
6679902537Polyploidywhen there is a whole extra set of chromosomes (ex. oversized fruits); Triploidy = 3 sets, Tetraploidy = 4 sets87
66799025384 alterations to gene structure1) Deletion: removal of chromosomal segment 2) Duplication: repetition of a segment 3) Inversion: reversal of a segment within a chromosome 4) Translocation: movement of a segment from one chromosome to another, non-homologous one88
66799025393 stages in cell cummunication1) Reception: cell detects a signal via connection of a ligand to a receptor protein 2) Transduction: the receptor protein converts the signal to a form that can cause a chemical response 3) Response: transduced signal triggers a specific cellular response89
6679902540Types of cell signaling (4)synaptic, paracrine, hormonal90
6679902541Examples of cell signalingG-protein coupled receptor, ligand-gated ion channels, steroid hormones (dissolved across plasma membrane, intracellular receptor)91
6679902542Second Messengers and Phosphorylation cascadesecond messengers and kinases spread throughout a cell that help amplify a cellular signal by a series of phosphorylation reactions (addition of phosphate)92
6679902543Virus structurenonliving, can't rproduce on their own; Capsid: protein coat that encloses the viral genome; Envelope: membrane that surrounds some viral capsids; Phage: protein encapsulated virus that attacks bacteria93
6679902544Lytic Cycle1) virus attaches to host cell 2) phage DNA enters cell and the cell's DNA degrades (*restriction enzymes in bacteria could destroy them) 3) synthesis of viral genomes and proteins 4) assembly of phages within cell 5) release of viruses, destroys cell94
6679902545Lysogenic Cyclethe virus inserts its DNA into a host cell, and its DNA integrates with the DNA of the host, allows it to be replicated without being attacked for long periods of time before entering the lytic cycle95
6679902546RetrovirusRNA virus that transcribes its RNA into DNA to insert into host cells (ex. HIV)96
6679902547Provirusa viral genome that is permanently inserted into a host genome97
6679902548Viral Transductioncontributes to bacterial genetic variation98
6679902549Repressible Operontrp operon - usually on, can be repressed. Repressor protein produced in inactive shape99
6679902550Inducible Operonlac operon - usually off, can be turned on. Repressor protein produced in active shape.100
6679902551cAMP and CAP regulated Operonwhen CAP is inactive, transcription continues at a much less efficient rate even in the presence of lactose101
6679902552Histone Acetylationthe loosening of chromatin structure (euchromatin), promotes transcription102
6679902553Histone Methylationthe condensing of chromatin structure (heterochromatin), prevents transcription103
6679902554Transcription Factors and EnhancersRNA polymerase requires the assistance of transcription factor proteins and enhancers or activators to successfully transcribe RNA104
6679902555Epigenetic Inheritanceinheritance of traits not directly related to nucleotide sequence (ex. fat, sickly, yellow rats were fed a methylated diet, resulted in offspring that were normal-sized, healthy, and brown)105
66799025565 Evidences for Evolution1) Biogeography 2) Fossil Record 3) Comparative Anatomy 4) Comparative Embryology 5) Molecular Biology106
66799025574 conditions for Hardy-Weinberg Equilibrium (not evolving)1) very large population 2) isolation from other populations 3) no mutations 4) no natural selection107
6679902558Microevolution vs. Macroevolutionchange in the gene pool of a population over several generations / large scale changes in a population that leads to the evolution of a new species108
66799025594 causes of Microevolution1) genetic drift 2) gene flow 4) natural selection109
6679902560Genetic Driftrandom change in gene frequency of a small breeding population: 1) Founder Effect = small population of organisms colonizes a new area, 2) Bottleneck Effect = sudden decrease in population size due to disaster110
6679902561Gene Flowloss/addition of alleles from a population due to imigration/emigration111
6679902562Nonrandom Matingselection of mates for specific phenotypes: 1) Assortative Mating = when individuals select partners with simple phenotypic characters, 2) Inbreeding = more recessive traits likely to come together112
66799025633 Modes of Natural Selection1) Stabilizing: favors intermediate, 2) Directional: favors one extreme phenotype, 3) Diversifying: favors both extremes113
6679902564Heterozygote Advantageheterozygotes for a trait are more likely to survive (ex. carriers of sickle cell anemia are immune to malaria)114
6679902565Biological Species Conceptpopulation whose members can create viable, fertile offspring (Problems: doesn't apply to extinct animals or asexually reproducing organisms)115
6679902566Prezygotic Reproductive Barriers1) Habitat Isolation 2) Behavioral Isolation (differing behaviors for attracting mates) 3) Temporal Isolation (mate at different times) 4) Mechanical Isolation 5) Gametic Isolation (unable to fertilize egg)116
6679902567Postzygotic Reproductive Barriers1) Reduced Hybrid Viability (disruption in embryonic stage) 2) Reduced Hybrid Fertility 3) Hybrid Breakdown (F1 is fertile, F2 is sterile or weak)117
6679902568Allopatric Speciationwhen populations become geographically isolated from the rest of the species and has the potential to develop a new species (ex. Adaptive Radiation: many diversely adapted species from common ancestor, Darwin's finches)118
6679902569Sympatric Speciationmembers of a population develop gametic differences that prevent them from reproducing with the parental type (polyploidy, not as common)119
6679902570Punctuated Equilibrium vs. Gradualismevolution occurs in short spurts of rapid change / each new species will evolve gradually over long spans of time120
6679902571Convergent Evolutiondifferent organisms that occupy similar environments come to resemble one another (ex. dolphins and sharks)121
6679902572EndosymbiosisOrigin of mitochondria and chloroplasts. Evidence: They have their own DNA and ribosomes, double membrane structure, grow and reproduce on their own within the cell122
6679902573Phylogenyevolutionary history of a species or group of related species123
6679902574Taxonomic groups from broad to narrow (8)Domain, Kingdom, Phylum, Class, Order, Family, Genus, Species124
66799025753 mechanisms in which bacteria transfer genetic materials1) Transformation: prokaryote takes up DNA from its environment 2) Transduction: viruses transfer genes between prokaryotes 3) Conjugation: genes are directly transferred from one prokaryote to another over a temporary "mating bridge"125
6679902576Types of Symbiotic RelationshipsMutualism (+, +), Commensalism (+, 0), Parasitism, (+, -)126
6679902577Factors that influence Transpiration RateTemperature: higher temperature, faster rate; Humidity: higher humidity, slower rate; Sunlight: more sun, faster rate; Wind: more wind, faster rate127
6679902578Lines of Immune Defense1st Line) skin oil and sweat, mucous; 2nd Line) nonspecific phagocytes and cytotoxic immune cells; 3rd Line) specific immune system128
6679902579Primary and Secondary Immune Response129
6679902580Active vs. Passive Immunitydepends on the response of a person's own immune system (artificial = vaccines) / immunity passed from one organism to another130
6679902581B cells vs. T cells (maturation)mature in bone marrow / mature in thymus131
6679902582Humoral vs. Cell-Mediated Immune Responses132
6679902583Non-steroid hormone vs. Steroid hormonetravels in bloodstream, binds to receptor on cell surface / travels in bloodstream, binds to receptor inside the cell133
6679902584Endotherms vs. Ectothermswarmed by heat generated by metabolism (mammals, birds) / generate little metabolic heat, warmed by environment134
6679902585Nichea position/role taken by a kind of organism within its community135
6679902586Resource Partitioningdivision of environmental resources by coexisting species136
6679902587Per capita Growth Ratebirth - death / total population137
6679902588Exponential vs. Logistic Growthin logistic growth, carrying capacity will limit the population's size138
6679902589Density-dependent RegulationDensity-independent: natural disasters, human impact, etc.139
6679902590Keystone Speciesspecies that exerts strong control on community structure not by numerical might but by their pivotal ecological roles or niches140
6679902591Energy Pyramideach energy level receives only 10% of the pervious level's energy141
6679902592Gross Primary Production vs. Net Primary Productiontotal amount of energy from light converted to chemical energy to organic molecules / GPP - energy used by primary producers for "autotrophic respiration"142
6679902593Carbon CycleConnect photosynthesis (fixation) to cellular respiration (CO2 release)143
6679902594Plasmidsa small, circular, double-stranded DNA molecule that carries accessory genes separate from those of a bacterial chromosome144
6679902595Recombinant DNAa DNA vector made in vitro with segments from different sources145
6679902596Restriction Enzymean enzyme that recognizes and cuts DNA molecules at specific nucleotide sequences (restriction sites), can then be used to create recombinant DNA146
6679902597Gel Electrophoresisanalyzing fragments of DNA (RFLPs) by their length and charge to determine genetic fingerprints and other genetic information147

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