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AP: Blood Flashcards

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6202806883HeartConsidered the pump of the circulating system0
6202813562Blood vesselsConsidered the conducting system of the circulating system1
6202816042BloodConsidered the fluid medium of the circulating system2
6202842619PlasmaWhole blood is made up of around 55% of this medium. This medium is mostly made up of water and dissolved proteins.3
6202825322RBCsThese formed elements make up 99.9% of blood's formed elements and are responsible for the transportation of oxygen.4
6202825323WBCsThese formed elements are part of the immune system5
6202827681PlateletsThese are not really cells; rather they are cell fragments involved in clotting.6
6202836220HemopoiesisThis is the process of producing formed elements from either myeloid or lymphoid stem cells.7
6202913126Myeloid hemopoiesisBlood formation in the bone marrow is called8
6202915475Lymphoid hemopoiesisLymphoid organs that produce lymphocytes undergo what process9
6202919600AlbuminsThis protein makes up 60% of plasma proteins and is important for maintaining osmotic pressure which maintains correct water balance between blood and tissues. It also acts like a buffer and carrier.10
6202950114GlobulinsThese proteins make up 35% of plasma proteins. There are at least 3 recognized forms of this protein: alpha, beta, and gamma.11
6202959930alpha and betaThese globulins transport fat-soluble vitamins and fats. They are produced in the liver along with other proteins.12
6202971979gammaThese globulins are antibodies released in immune response. They came from WBCs called B lymphocytes.13
6202988880FibrinogensThese are proteins that make up about 4% of plasma protein, associated with the clotting of blood. They produce long strands of proteins called fibrin.14
6202995279SerumThe liquid part of a blood sample in which dissolved fibrinogen has been converted to solid fibrin is called? Think of it like this: It's basically just plasma without the clotting protein.15
6203039470SodiumMost important plasma cation, making up about 90% of them. These ions are important for the osmolarity of blood. People with HBP are advised not to increase their intake of what?16
6203050200Red Blood Cell CountThis test reports the number of RBCs in 1 microLiter whole blood.17
62030606184.5-6.3, 4-5.5What is the normal RBC count (in millions) for a male and female adult respectively?18
6203064323HematocritThis is the packed cell volume, PCV. It is a test to measure the percentage of RBCs in centrifuged whole blood.19
620306929940-54, 37-47What is the PCV of a male and female adult respectively?20
6203074604Buffy coatThe "line" between plasma and RBCs in centrifuged whole blood that is composed of WBCs and platelets.21
6203153409HemoglobinThis is the protein molecule on RBCs that allows for the transportation of respiratory gases. It is a tetra peptide with 2 alpha chains and 2 beta chains.22
620316394814-18, 12-16What is the normal hemoglobin count (in g/dL of whole blood) in a male and female adult?23
6203170227IronWhat is the metal that is bound to the heme of each of the chains on hemoglobin?24
6203205870Fetal hemoglobinA strong form of this RBC protein. It consists of 2 alpha chains and 2 gamma (instead of beta) chains. This is only found in embryos and allows fetuses to take oxygen directly from the mother's blood.25
6203245831CarbaminohemoglobinThis form of RBC protein is associated with the release of O2 to peripheral tissues in the presence of low O2 levels. And the binding and transportation of CO2 to the lungs.26
6203256344AnemiaWhen hematocrit and hemoglobin levels are below the normal. This condition is usually caused by a lack of oxygen getting to cells.27
6203305262ErythropoietinThis hormone produced in the kidney can be responsible for some forms of anemia when the kidneys do not produce this enough. This hormone is responsible for RBC production.28
6203263809Hemorrhagic anemiaLow RBC count: Anemia resulting from bleeding29
6203266581Hemolytic anemiaLow RBC Count: Anemia resulting from RBC destruction30
6203270730Aplastic anemiaLow RBC Count: Anemia resulting from destruction to myeloid tissue31
6203286294Iron deficiency anemiaLow Hb Content: Anemia caused by not enough iron in diet32
6203290236Pernicious anemiaLow Hb Content: Anemia caused by lack of vitamin B1233
6203325572ThallasemiaAbnormal Hb: A genetic disorder in which RBCs are malformed making it harder for O2 to bind. Either the alpha or beta chains are affected but is not universally specific. It can happen to either chains34
6203350103Sickle cellAbnormal Hb: A genetic disorder in which RBCs are malformed making it harder for O2 to bind. Beta chain point mutation (from E to V) creates an hydrophobic patch. The altered RBCs clump together making it harder to pass through blood vessels and eventually starving tissues of O2.35
6203404846HemolysisRupturing of RBCs membranes36
6203413001HemoglobinuriaHemoglobin breakdown products are found in urine due to excessive hemolysis in blood stream37
6203416983HematuriaWhole RBCs are found in urine due to kidney or tissue damage.38
6203426002HypoxemiaO2 deficiency in blood39
6203428224EmphysemaLess lung tissues are able to oxygenate the blood40
6203431766PolycythemiaCategory of disorders characterized with abnormally high levels of RBCs.41
6203436867Polycythemia veraCancerous production of RBC where the erythropoeitc line of the bone marrow is affected42
6203446591Secondary polycythemiaExcessive production of RBCs caused by anything other than cancer, ex: dehydration, changes in altitude, and pregnancy.43
6203494858BiliverdinPhagocytes convert the heme of RBCs into this. This will further be converted into bilirubin; which is secreted by the liver in the form of bile. Microbiota will convert bilirubin into uorbilins and stercobilins.44
6203511801TransferrinThe transport protein that carries Iron to the liver during RBC recycling.45
6203516858Hemosiderin or FerritinThe storage proteins that store iron in the liver during RBC recycling.46
6203539019ErythropoiesisRBC cell formation that only occurs in the myeloid tissue or Red bone marrow. This process takes about 3-5 days.47
6203542414HemocytoblastsThese are stem cells in the bone marrow that divide to produce myeloid stem cells or lymphoid stem cells.48
6203560804Pluripotent stem cellsHemocytoblasts are a type of these cells. They can differentiate into cells that the body needs.49
6203632857ProerythroblastDay 1 of Erythropoiesis50
6203638524Basophilic erythroblastDay 2 of Erythropoiesis51
6203641360Polychromatic erythroblastDay 3 of Erythropoiesis52
6203644516NormoblastDay 4 of Erythropoiesis: nucleus is ejected53
6203646472ReticulocyteDays 5-7 of Erythropoesis54
6203700389Myeloid stem cellsStem cells that can become RBCs or some WBCs55
6203702202Lymphoid stem cellsStem cells that exclusively become lymphocytes.56
62037762180.8Normal reticulocyte count; which is a test used to determine the percentage of circulating reticulocyte.57
6203781941ReticulocytosisThis is a disorder resulting from elevated levels of reticulocytes circulating.58
620380225982-101What is the average volume ( in micrometer cubed) of a single RBC? the Mean Corpuscular volume (MCV) measures this.59
6203812470MacrocyticLarger than average volume of a RBC.60
6203815178MicrocyticSmaller than average volume of RBC61
620381796527-34What is the average amount of Hemoglobin (in pg/microLiter) in one RBC? The Mean corpuscular hemoglobin concentration (MCHC) measures this.62
6203824397HyperchromicHigher than average Hb count in one RBC63
6203826991HypochromicLower than average Hb count in one RBC64
6203846306AgglutinogensThese are the antigens on the surface of RBCs. They are constantly screened by the immune system.65
62039780636000-9000Normal WBCs count in blood. This number usually increases in the presence of foreign pathogens.66
6204038705GranulocytesThese types of WBCs contain granules easily visible under the microscope.67
6204152470AgranulocytesThese types of WBCs do not contain granules.68
6204161552NeutrophilsMost abundant WBCs (50-70%), first to attack bacteria; usually rises in response to bacterial infection. Can perform phagocytosis. They are also called polymorphonuclear leukocytes.69
6204191754EosinophilsMakes up 2-4% of circulating WBCs. They attack large parasites. These are also called acidophils. They are also sensitive to allergies and control inflammation70
6204220053BasophilsMake up less than 1 percent of circulating WBCs. They are small and accumulate in damaged tissue. These cells release histamine (vasodilator) and heparin (prevents blood clotting)71
6204243083MonocytesMake up 2-8% of circulating WBCs. They are large and spherical. When they enter peripheral tissues, they become macrophages. They increase in response to viral/ fungal infections. They are engaged in phagocytosis. They secrete substances that attract immune cells and fibroblasts to injured areas.72
6204256302LymphocytesMakes up 20-30% of circulating WBCs. These are larger than RBCs and they migrate in and out of the blood. They are mostly found in connective tissues and lymphatic organs. They are a part of the body's specific defense system.73
6204269842B cellsThese types of lymphocytes differentiate into cells that produce antibodies.74
6204273976T cellsThey types of lymphocytes attack viruses, fungi, translated cells, cancers, some bacteria, and some allergic reactions.75
6204279154Natural killer cellsThese types of lymphocytes attach a wide range of infectious microbes and certain spontaneously arising tumor cells.76
6204306937Leukopeniaabnormally low WBC count77
6204308935leukocytosisabnormally higher WBC count78
6204311198leukemiaextremely high WBC count; cancerous.79
6204377765150-500Normal platelet count (in thousands per microL)80
6204380213ThrombocytopeniaAbnormally low platelet count81
6204382058ThrombocytosisAbnormally high platelet count.82
6204418151ThrombocytopoiesisThe process of platelet production. This occurs in the bone marrow.83
6204446567HemostasisThis is a 3 step process of clotting84
6204449642Vascular phaseFirst stage in hemostasis. This, itself, occurs in 3 steps. This step lasts for 30 minute where spasms are triggered and contractions try to narrow vessels.85
6204574490Platelet PhaseSecond stage in hemostasis. This begins 15 seconds after injury where platelets adhere to sticky surfaces and aggregate to form a plug.86
6204718449Coagulation PhaseThird stage in hemostasis. This begins 30 seconds or more after injury. This final step involves the usage of fibrin threads to reinforce the platelet plug originally formed in the previous step.87
6205148592thrombusa clot that forms and persists in an unbroken vessel. This may block vessel and cause death of that tissue as in heart attack.88
6205156068coronary thrombosisClot in the heart89
6205158530Embolusa detached clot which may also eventually cause blockage and lead to death.90

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