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13993037851AneuploidyAbnormal number of chromosomes.0
13993040686Klinefelter's syndromemale extra X;;;XXY1
13993048805Turner's syndromefemale with only 1 X2
13993057708XYYmale extra Y3
13993139815SRY geneon the Y chromosome initiates testes development/ "maleness"; female is "default" in humans (X chromosome does have genes that regulate female development)4
13993147023Gonads begin development5th week as gonadal ridges5
13993156386Effects pregnancy has on motherIncrease in progesterone/estrogen → nausea & morning sickness Increase in urine output because of an increase in wastes and pressure on the bladder Increase in tidal volume and dyspnea (difficult breathing) may occur later in pregnancy Use of lipids/proteins instead of glucose for metabolism → glucose for baby, but can cause gestational diabetes Increase in blood volume, but a decrease in BP due to widespread vasodilation; varicose veins common Increase in cardiac output & GFR; decrease in plasma osmolality → potential anemia (decrease Hct) Reproductive organs become engorged with blood & breasts enlarge and areolas darken Increase in skin pigmentation → chloasma ("pregnancy mask") Weight gain of ~13 kg (28 lbs) on average Relaxin causes pelvic ligaments and the pubic symphysis to relax to ease birth passage6
13993164923Chorionencloses all other layers; composed of trophoblast and extraembryonic mesoderm7
13993169941Amnioninnermost membrane that contains the amniotic fluid; provides buoyancy and thermoregulation8
13993177362Yolk sacfirst site of RBC formation; integrates with the gut9
13993185286Allantoisbase of the umbilical cord; integrates with the bladder10
13993190280Umbilical cordincludes embryonic connective tissue, 1 umbilical vein, and 2 umbilical arteries11
13993195504Egg passageOvary-> fimbriae-> uterine/fallopian tube-> uterus12
13993200702Ampulladistal expansion with infundibulum (expansion) near ovary; usual site of fertilization13
13993269245Leydig cellsMale reproductive system Interstitial (leydig) cells outside the seminiferous tubules produce androgens14
13993279579the location where the fertilized zygote implantsEndometrium15
13993290500Mittelschmerz:twinge of pain sometimes felt at ovulation16
13993297151Luteal Phaseperiod of activity of the corpus luteum17
13993316373Phase 1: Zygote Phase 2: 2 Blastomeres at 36 hours with continued division Phase 3: Morula- solid ball of about 16 cells at 72 hrs Phase 4: Blastocyst- fluid filled ball of cells at day 3 to 4, inner cell mass becomes conceptus and trophoblast lies superficially; reaches uterus for implantation18
13993321786Fraternal twinsIf more than 1 secondary oocyte is released from the ovaries AND is fertilized by sperm19
13993332532Sustentacular (sertoli) cellslarge supportive cells that extend through the wall of the tubule and surround developing cells to provide nutrients and signals to developing cells, dispose of excess cytoplasm sloughed off during spermatogenesis, & secrete testicular fluid into lumen for transport of sperm; tight junctions that form the blood/testis barrier (prevent antigens from escaping) divide the wall into two components20

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