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| 10169583198 | Iroquois | A league of Iroquois tribes including originally the Mohawk, Oneida, Onondaga, Cayuga and Seneca; after 1722 they were joined by the Tuscarora. | 0 | |
| 10169583199 | Colombian Exchange | Trade of natural resources,technology, and disease between the NEW WORLD + OLD WORLD | 1 | |
| 10169591069 | Reformation | A 16th century religious movement marked ultimately by rejection or modification of some Roman Catholic doctrine and practice and establishment of the Protestant churches. | 2 | |
| 10169591070 | Columbus | Christopher Columbus was an Italian-born explorer who set sail in August 1492. | 3 | |
| 10169594463 | Tenochtitlan | The capital city of the Aztec Empire from the middle of the 1300s to the early 1500s. | 4 | |
| 10169595374 | Mestizos | A person of mixed racial or ethnic ancestry, especially, in Latin America, of mixed | 5 | |
| 10169595375 | Small Pox | a pox virus that is transmitted from person to person. Smallpox is the only disease that has been completely wiped out throughout the world. | 6 | |
| 10169597759 | Pizarro | Spanish conquistador who conquered the Incas in what is now Peru and founded the city of Lima (1475-1541). | 7 | |
| 10169597760 | Maize | technical or chiefly British term for corn. | 8 | |
| 10169599581 | Encomienda System | A labor system instituted by the Spanish crown in the American colonies. In this system. | 9 | |
| 10169601586 | Cortes | Spanish conquistador who defeated the Aztecs and conquered Mexico (1485-1547) | 10 |
