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| 4737109154 | Corn/Maize | Very popular in the south west. Caused nomads to settle Increase in population Transformed societies from hunters and gatherers to farmers. | 0 | |
| 4737109155 | horse | Bison hunting became easy. Native with horses became stronger militarily. | 1 | |
| 4737109439 | disease/smallpox | 1500's many americans died from exposure to small pox when the Europeans initially came. | 2 | |
| 4737109440 | Encomienda System | a Spanish system which allowed the government to "commend" or give Indians to certain colonists in return for the promise to try to Christianize them | 3 | |
| 4737111533 | land bridgeTheory | 4 | ||
| 4737111534 | Maya | A Mesoamerican civilization of Central America and southern Mexico. Achievements include mathematics, architecture, and a 365 day a year calendar. They flourished between the 4th and 12th centuries C.E.. | 5 | |
| 4737111633 | Aztec | Indian peoples in Mexico who shaped stunningly sophisticated civilizations with advanced agricultural practices, elaborate cities, far-flung commerce, and human sacrifices; their population reached up to 20 million | 6 | |
| 4737111634 | Inca | Advanced and wealthy civilization centered in the Andes mountain region; aided by smallpox, the were conquered in 1533 by Francisco Pizarro | 7 | |
| 4737111841 | Conquistadors | spanish word for "conquerors"; fanned out across the Caribbean and Americas | 8 | |
| 4737111842 | Hernan Cortez | Spaniard who conquered Aztecs in Mexico 1519-1521; had two interpreters with him | 9 | |
| 4737112184 | Francisco Pizzaro | Spanish conquistador who conquered Incas (in Peru) in 1532, adding to Spain's amount of silver | 10 | |
| 4737112185 | Roanoke Island | Established in 1587. Called the Lost Colony. It was financed by Sir Walter Raleigh, and its leader in the New World was John White. All the settlers disappeared, and historians still don't know what became of them | 11 | |
| 4737112332 | compass | an instrument containing a magnetized pointer that shows the direction of magnetic north and bearings from it | 12 | |
| 4737112333 | Printing Press | The printing press was invented in the Holy Roman Empire by the German Johannes Gutenberg around 1440, based on existing screw presses | 13 | |
| 4737112556 | Ferdinand And Isabella | king of Spain; married Isabella of Castile which united the nation in the late 15th century | 14 | |
| 4737112557 | protestant reformation | a religious movement of the 16th century that began as an attempt to reform the Roman Catholic Church and resulted in the creation of Protestant churches | 15 | |
| 4737112989 | Christopher Columbus | Italian seafarer who sailed for Spain; sighted an island in the Bahamas on October 12, 1492 seeking a new water route to the Indies; thought Americas were the Indies | 16 | |
| 4737112990 | Columbian exchange | the transfer of plants, animals, and diseases between the Americas and Europe, Asia, and Africa | 17 | |
| 4737113124 | treaty of tordesillas | treaty between Spain and Portugal (1494) that divided lands of New World; majority went to Spain, but Portugal received lands in Africa, Asia, and Brazil | 18 | |
| 4737113125 | slave trade | The Atlantic slave trade or transatlantic slave trade took place across the Atlantic Ocean from the 15th through 19th centuries | 19 | |
| 4737113378 | Bartolome de las casas | 1566) was a 16th-century Spanish historian, social reformer and Dominican friar. He became the first resident Bishop of Chiapas, and the first officially appointed "Protector of the Indians". | 20 |
