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B12 Flashcards

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4464428928Causes of low b12Diet-strict a vegans or failure of absorption.0
4464428929Requirements to absorb B12Acid to release food bound cobalamin. Secretion of intrinsic factors from healthy parietal cells. Normal pancreatic secretions. Normal ideal function.1
4464428930Disadvantages of schilling testTime consuming, involves radioisotopes and collection of urine. Results difficult to interpret, distinction between illegal and gastric disease is not clear cut2
4464428931Evidence of autoimmune gastritisAntibodies to parietal cells and intrinsic factor. Low acid output.3
4464428932Hb low, mean cell volume high, hyper segmented neutrophils, bone marrow unresponsive to usual stimulus of anaemia. Iron and folate normal, B12 lowPernicious anaemia related to autoimmune gastritis4
4464428933Requirement for normal erythropoesisisIron. Folate. B12.5
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