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Biochemistry Flashcards

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7787330446U= q-wq= heat absorbed by the surroundings w= work done by the system on the surroundings0
7787357177Enthalpy (E)ΔH= q1
7787399222Entropy (S) (JK^-1)S = kB lnW W = the number of energetically equivalent ways of arranging components in a system kB = Boltzmann constant2
7787423104Free Energy (G)If ΔG of a process is negative, the process is called "exergonic"; If ΔG of a process is positive, the process is called "endergonic"3
7787424681ΔG = ΔH −TΔSAt constant P and T, ΔG will be negative for a spontaneous process.4
7787441226ΔG0 in equilibriumΔG0= −RTlnKeq5
7787792641ΔG and the rate of a processgoing from the state with higher G to the state with lower G, but does not ensure that this process will proceed at a fast rate.6
7787797571Eukaryotic plant cellMitochondrion power house of the cell , Chloroplast photosynthesis, energy converter, Nucleus contains chromosomal DNA7
7787803653Eukaryotic animal cellmitochondria (powerhouse of the cell, lysosome (protein degradation), Organelles differ in major ways from the cytoplasm, e.g. in: 1. Protein content 2. DNA & RNA content 3. Cofactors 4. pH8
7787810015Malaria parasiteMicroneme and rhoptry provide protein for red blood cell entry for invasion of host cell9
7787818220lipidsglycerol backbone, 2 fatty acids (C 1&2), and a phosphatidylcholine10
7787827808prokaryotesnot as compartmentalized, lack protection from harmful events inside an organelle and specialized membrane bound machineries11
7787832273Escherichia coli cell (rapidly dividing)Number of all proteins inside cell ~ 2,600,000 Number of external proteins (flagella & pili) ~ 1,000,000 Number of all proteins of an E. coli cell ~ 3,600,00012
7787834802proteinscomposed of amino acids13
7787835212nucleic acidscomposed of nucleotides14
7787836130polysaccharidessugars15
7787838250tRNA3 prime terminus that accepts amino acid, and three nucleotide anti codon, and has a phospho-ribose backbone.16
7787856452glucosecellulose and glycogen OH down alpha, and beta is down17
7787860778alpha-amylose1-4 linkage (glycogen by adding branches every 8 to 14 glucose units)18
7787864206ATP19
7787868930non-covalent interactions (van der waals interactions)dipole-dipole > dipole induced dipole > London dispersion forces20
7787888279H2Obent 104 degrees, H bonding, O-O distance 2.74 angstroms, (i) the O-H covalent bond distance of ~0.97 Å + (ii) the H vdW-radius of ~1.2 Å + (iii) the O vdW-radius of ~1.4 Å,21
7787912646water as icefour interactions,22
7790986133Hydrocarbons and waterThe entropy S is smaller (thus, less favorable) for a hydrocarbon in water than when surrounded by hydrocarbons.... NOTICE THAT ΔH IS ZERO water molecules around hydrocarbon are restricted in rotational freedom23
7791193917"amphiphilic" or amphipathicmolecules with both polar and nonpolar segments24
7791220437clustering of amohiohilic moleculesfewer water molecules are restricted in rotational freedom. Therefore, the entropy of the system is increased by clustering lipids25

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