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Biochemistry Flashcards

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11814855845Structure and Function of Bio-moleculesMost are organic molecules Extremely large Complex 3D shapes Function depends on 3D shape Stereochemistry0
11866699446D-IsomerRight handed forms1
11866705609L-IsomerLeft handed forms2
11866716356MonomersBuilding blocks3
11866720431PolymersGroups of monomers that bond together4
11866735540When putting monomers together, you lose H2ODehydration Synthesis5
11866750011Can be reversed by adding water to break molecules downHydrolysis6
11866761751CarbohydratesPolar Water soluble Have lots of -OH Can either be a ketone or aldehyde Carbonyl Three types: monosaccharides, oligosaccharides, polysaccharides7
11866796895MonosaccharidesMade of monomers Simplest form Simple sugars/carbs8
11866812585Oligosaccharides2-20 monosaccharides 2 mono = disaccharide 3 mono = trisaccharide9
11866836125Polysaccharides>20 monosaccharides Complex sugars10
11866847458Classification of monosaccharides1. Type of carbonyl group Aldehyde - aldose sugar Ketone - ketone sugar 2. Number of carbon atoms 3 C = triose sugar 4 C = tetrose sugar 5 C = pentose sugar 6 C = hexose sugar11
11866914094Monosaccharides to knowGlucose - aldohexose sugar Galactose - aldohexose sugar Fructose - keothexose sugar Ribose - aldopentose sugar12
11866961799Glycosidic BondBond that bonds two monosaccharides together13
11866974253DisaccharidesSucrose (table sugar) Glucose + Fructose Lactose (milk sugar) Galactose + Glucose Maltose (malt sugar) 2 Glucose bound together14
11866997128GlucansOnly building block is glucose15
11867004335Three types of glucansStarch, glycogen, and cellulose16
11867011740StarchStorage form of glucose in plants Amylose - continuous chain of glucose Amylopectin - has branches of glucose ever 24-3017
11867034105GlycogenStorage form of glucose in animals Structure same as amylopectin, branches every 8-10 Found in liver and skeletal muscle18
11867045782CelluloseFiber Main structural feature of plant cell walls19
11867053270Function of CarbohydratesEnergy (glucose) Structure (cellulose) Information carriers20
11867070032LipidsDiverse group of molecules Nonpolar molecules Water insoluble21
11867083701Fatty Acids (FA)Long chain of carboxylic acids > 16 C atoms Even # of C atoms Saturated (C-C) or Unsaturated (C=C)22
11867103435MUFAMonounsaturated fatty acid23
11867109836PUFAPolyunsaturated fatty acid24
11867121599C=C ClassificationC numbering starting at carboxyl end Omega numbering starting at methyl end25
11867146254Delta SystemUses C numbering and indicates position of C=C26
11867177493Omega (w) SystemUses omega numbering and indicates position of 1st C=C27
11867187552Fatty Acid FunctionMakes energy (2nd behind glucose) More energy dense Brain and RBC dont use FA, they use glucose Makes other lipids Structure (membranes) Every double bond kinks the chain.28
11867246760Fatty acid state at room tempSaturated - solids Unsaturated - liquids/oils29
11867251970Wax functionsIs protective Waterproofing/Buoyancy30
11867277390Triglycerides functionsEnergy storage - adipose tissue Insulation Protection31
11867298907Phospholipids32
11867307371SteroidsCholesterol 1. used for structure in cell membrane Adds rigidity 2. Makes bile salts Bile acids leave through poo and are made in the liver Stored in gallbladder 3. Can make steroid hormones33
11867343390Steroid Hormones FunctionCarries information34
11867373907Progestin (progesterone)Made in ovary and all steroid synthesizing cells Menstruation Pregnancy35
11867395099Mineralocorticoids (aldosterone)Regulates fluid and electrolyte balance Increases blood pressure Adrenal gland Kidneys36
11867429828Glucocorticoids (cortisol)Controls general body physiology Regulates energy production, immune response, and inflammation Stress hormones Adrenal gland37
11867473811Androgens (testosterone)Made in testes/ovary Male sex hormones Anabolic molecule (growth of muscle and bone) Estrogens E1, E2, E3 In ovary Female sex hormones38
11867507844Eicosanoidslipids derived from arachidonic acid 20 C - 20 C FA39
11867521512ProstaglandinsStimulates fever Pain stimulation Inflammation Physiology of eye Male and female reproduction40
11867541911ThromboxanesCoagulation41
11867552363LeukotrienesRespiratory physiology Bronco constrictors (asthma)42
11867615190enzyme-catalyzed reaction43
11867649934KmMeasure of binding strength44
11867657129VmaxHow fast reaction occurs45
11867663059Protein functions"Proteins are life" They do everything They form structure (cell, organelles, tissue, organs) They transport Moves things across membranes Information carriers (hormones) Function as enzymes46
11867705569primary structure of proteinsequence of amino acids (not random) every protein has its own primary and unique 1 structure Only thing necessary is peptide bonds47
11867719770secondary structure of proteinDiscrete 3D shapes that from in certain parts of proteins Each protein has ts own unique number of 2 structures Hydrogen bonds formed between side chains48
11867769925tertiary structure of proteinoverall 3D shape of whole proteins 2 major types of 3D shapes: globular proteins and fibrous proteins Hydrogen bonds/Hydrophobic force/Disulfide bond Some proteins stop at this level of structure and are functional, some are not ready49
11867809097quaternary structure of a protein2 or mroe polypeptides associating together to create a functional protein Hydrogen bonds/Disulfide bonds50
11867826597EnzymesBiological catalyst Speeds reactions without being used up 99.9% catalyzed by enzymes Delta G = favorable reaction51
11867861030Affect Enzyme ActivityTemperature, pH, inhibitors52
11867877934Competitive inhibitorsCompetes with substrate, increases Km value53
11867890931Noncompetitive inhibitorsdecreases Vmax, blocks ability to form product54
11867902265Irreversible inhibitorspermanent inhibitor, decreases Vmax55
11867913289Nucleic Acids2 major types DNA- Deoxyribonucleic Acid RNA- Ribonucleic Acid56
11867934679Nucleotidesbuilding blocks Made up of 3 components: sugar, nitrogenous base, and a phosphate group57
11867981952SugarsDNA- Deoxyribose (aldopentose with one missing -OH) RNA- Ribose (aldopentose sugar)58
11867998108Nitrogenous Base2 main types: Purines and Purimidines59
11868009687PurinesAdenine and Guanine60
11868018986Pyrimidinescytosine, thymine, uracil61
11868030218NucleosidesSugar + Base62
11868048364ATPPrimary energy molecule in all living organisms63
11868106296Nucleic acid functionsStorage and transmission of genetic information64
11868114370Central Dogma of Biology65
11868124349DNAStorage of genetic information66
11868124487RNATransmitter of genetic information67
11868137470ProteinsGenetic information in action; is realized68
11868172502ReplicationHappens in nucleus Mitosis/Meiosis69
11868204234Messenger RNA (mRNA)Info making proteins70
11868208463Transfer RNA (tRNA)Deliver amino acids to ribosomes71
11868215440Ribosomal RNA (rRNA)Structure of ribosomes72

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