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BIOL 1406 Chapter 15 Meiosis Flashcards

BIOL 1406 Chapter 15 Meiosis

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427954831Geneticsscientific study of heredity and hereditary variation0
427954832Heredity/inheritancethe transmission of traits from one generation to the next1
427954833Hereditary variationdemonstrated by the differences in appearance that offspring show from parents and siblings2
427954834Geneshereditary units in which parents endow their offspring with coded information; made up of segments of DNA, the polymer that consist of four different nucleotides (A, G, C and T)3
427954835GametesGenes are passed to the next generation through reproductive cells (sperm and eggs); contain a single chromosome set (n)4
427954836Chromosomesexcept for small amounts of DNA in mitochondria and chloroplasts, the DNA of a eukaryotic cell is packaged as THIS in the nucleus; humans have 46; each consists of a single long, linear DNA molecule elaborately coiled in association with various proteins; represented by the letter n5
427954837Somatic cellany cell other than a gamete6
427954838Karyotypechromosomes are arranged in pairs, starting with the longest chromosome, the resulting ordered display7
427954839Homologous chromosomestwo chromosomes in each pair have the same length, centromere position and staining pattern8
427954840Autosomal chromosomesThe 22 pairs of chromosomes that do not determine sex9
427954841Diploid cellAny cell with two chromosome sets (2n)10
427954842FertilizationThe union of gametes, culminating in the fusion of their nuclei11
427954843ZygoteFertilized egg; diploid b/c of 2 haploid sets of chromosomes, one set from each parent12
427954844Germ cellsSpecialized cells where gametes develop13
427954845Meiosisreduces the number of chromosome sets from two (diploid=2n) to one (haploid=n), producing 4 haploid daughter cells that differ genetically from each other and from the parent cell. Each haploid daughter cell has a random mix of chromosomes14
427954846Prophase 1typically occupies more than 90% of the time required for meiosis; Chromosomes begin to condense; synapsis and crossing over occurs15
427954847Synapsishomologous chromosomes loosely pair up, aligned gene by gene16
427954848Crossing overnonsister chromatids exchange DNA segments17
427954849Tetrad/bivalentgroup of four sister chromatids18
427954850ChiasmataX-shaped regions where crossing over occurred; each tetrad usually has one or more19
427954851Prometaphase 1The spindle apparatus is complete, and the chromatids are now attached to kinetochore microtubules; Pairs of sister chromatids, one member of each homologous pair, are attached to opposite poles20
427954852Metaphase 1the tetrads line up at the metaphase plate, with one replicated chromosome facing each pole Kinetochore microtubules from one pole are attached to the kinetochore of one replicated chromosome of each tetrad Kinetochore microtubules from the other pole are attached to the kinetochore of the other replicated chromosome21
427954853Anaphase 1pairs of homologous chromosomes separate; Connections between the bivalents break, but not the connections that hold the sister chromatids together One replicated chromosome moves toward each pole, guided by the spindle apparatus Sister chromatids remain attached at the centromere and move as one unit toward the pole22
427954854Telophase 1 and Cytokinesisin the beginning, each half of the cell has a haploid set of replicated chromosomes; each chromosome still consists of two sister chromatids Replicated chromosomes have reached their respective poles and decondense and nuclear membranes reform Cytokinesis usually occurs simultaneously, forming two haploid daughter cells23
427954855Meiosis 2There is no S phase before The sorting events during are very similar to those of mitosis Sister chromatids are separated during anaphase II, unlike anaphase I24
427954856Prophase 2a spindle apparatus forms. There are no tetrads or bivalents.25
427954857Prometaphase 2Kinetochore microtubules attach to replicated chromosomes (each still composed of two chromatids) and move them toward the metaphase plate.26
427954858Metaphase 2the sister chromatids (replicated chromosomes) are arranged at the metaphase plate. Because of crossing over in meiosis I, the two sister chromatids of each chromosome are no longer genetically identical! The kinetochores of sister chromatids attach to microtubules extending from opposite poles.27
427954859Anaphase 2the sister chromatids separate. The sister chromatids of each chromosome now move as two newly individual chromosomes toward opposite poles.28
427954860Telophase 2In telophase II, the chromosomes arrive at opposite poles. Nuclei form, and the chromosomes begin decondensing. Cytokinesis separates the cytoplasm. At the end of meiosis, there are four daughter cells, each with a haploid set of unreplicated chromosomes. Each daughter cell is genetically distinct from the others and from the parent cell.29
427954861Mitosisconserves the number of chromosome sets, producing 2 daughter cells that are genetically identical to the parent cell30
427954862Allelesalternate versions of the same gene that occupy the same locus31
4279548633 things contributing to genetic variation-Independent assortment of chromosomes -Crossing over -Random fertilization32
427954864Independent Assortment of Chromosomes-One aspect of sexual reproduction that generates genetic variation is the random orientation of homologous pairs of chromosomes at metaphase of meiosis I. -each pair of chromosomes sorts maternal and paternal homologues into daughter cells independently of the other pairs. -Each pair may orient with either its maternal or paternal homolog closer to a given pole -The number of combinations possible when chromosomes assort independently into gametes is 2n, where n is the haploid number. -For humans (n = 23), so then, there are more than 223 or 8 million possible combinations of chromosomes.33
427954865Crossing over-produces recombinant chromosomes, individual chromosomes that carry genes (DNA) derived from two different parents. -homologous chromosomes pair up gene by gene and homologous portions of two nonsister chromatids trade places. -contributes to genetic variation by combining DNA from two parents into a single chromosome.34
427954866Random fertilization-adds to genetic variation because any sperm can fuse with any ovum (unfertilized egg). -The fusion of two gametes (each with 223 or 8.4 million possible chromosome combinations from independent assortment) produces a zygote with any of about (223 x 223) 70 trillion diploid combinations. -If we factor in the variation brought about by crossing over, then the number of possibilities is truly astronomical35

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