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Biology Chapter 12: DNA and RNA Flashcards

Key words of Chapter 12 of the 2004 edition of Prentice Hall 's Biology textbook. Also includes some information from Chapters 13 and 14.

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635564882DNAA long molecule made up of nucleotides that stores and transmits the genetic information from one generation of an organism to the next.0
635564883ChromatinConsists of DNA bound to protein in nucleus. When a cell divides the chromatin condense to form chromosomes1
635564884Nucleotidesmonomer of DNA. Made up of three basic components: 5-carbon sugar, a phosphate group, and a nitrogenous base (Adenine, Thymine, Guanine, and Cytosine. In RNA Uracil replaces Thymine)2
635564885PurinesA group of compounds that include Adenine and Guanine. Have two rings in their structures3
635564886PyrimidineA group of compounds that include Cytosine and Thymine. Have one ring in their structure4
635564887Chargaff's RuleAdenine pairs with Thymine and Guanine pairs with Cytosine. He discovered that the ratio between the pairs were almost the exact same5
635564888Double Helixstructure of DNA, has two DNA strands wound around eachother. The two strands are held together by hydrogen bonds that formed in between bases6
635564889Base pairingAdenine can only pair with Thymine and Cytosine can only pair with Guanine. Hydrogen bonds form between the pairs to hold the double helix together7
635564890HistoneProteins that DNA coils around8
635564891NucleosomeThe DNA and histone molecules form a beadlike structure called a nucleosome9
635564892Amino AcidsMonomer of proteins10
635564893DNA replicationDuring this process, the DNA molecule separates into two strands, then produces two new complementary strands. Each strand of the double helix of DNA serves as a template, or model, for the new strand.11
635564894DNA polymeraseenzyme that joins individual nucleotides to produce a DNA molecule, which is a polymer. It also proofreads each new DNA strand, helping to maximize the odds that each molecule is a perfect copy of the original DNA.12
635564895Genescoded DNA instructions that control the production of proteins within the cell.13
635564896RNAContains the genetic code for making proteins14
635564897mRNAServe as messengers from DNA in nucleus to the rest of the cell15
635564898rRNAHelps the ribosome make proteins16
635564899tRNATransfers an amino acid to the ribosome17
635564900TranscriptionThe process in which RNA is made. RNA polymerase separates a DNA strand and uses it as a template with which to make a complimentary RNA strand18
635564901PromoterRegions on the DNA that signal the RNA polymerase to start copying at that point on the chain19
635564902CodonThree consecutive nucleotides that specify a single amino acid that is to be added to the polypeptide (protein) located on the mRNA20
635564903TranslationThe process in which proteins are made. mRNA enters a ribosome and provides the code for which amino acids should be put together. tRNA brings the amino acid to the ribosome so it can form a polypeptide21
635564904PolypeptideMany amino acids held together by peptide bonds22
635564905Anti-codonComplimentary bases on a tRNA to match the mRNA codon23
635564906Gene mutationChanges in the nucleotides24
635564907Point mutationA gene mutation that only changes a single point on the DNA sequence25
635564908Insertion (point mutation)when one nucleotide is added26
635564909Deletion (chromosomal and point mutation)when one nucleotide is taken out27
635564910Substitution (point mutation)when one nucleotide is switched with a different nucleotide28
635564911Frameshift mutationOccurs after an insertion or deletion; all codons are changed to accommodate the extra/one less nucleotide. Can alter protein so much that it is unable to perform its function29
635564912Chromosomal mutationInvolve changes in the number or structure of chromosomes. Mutations may change the locations of genes on chromosomes, and may even change the number of copies of some genes. Changes in whole chromosomes.30
635564913Deletion (chromosomal mutation)When one nucleotide is taken out31
635564914Duplication (chromosomal mutation)When a chromosome produces extra copies of parts of the chromosome32
635564915Inversion (chromosomal mutation)When a part of the chromosome reverses direction33
635564916TranslocationWhen one part of the chromosome breaks of and transfers to another chromosome34
635564917PolyploidyWhen an organism has extra sets of chromosomes35
635564918TransformationAny change in an organism that alters its general character and mode of life36
635564919Recombinant DNADNA molecules that are produced by combining DNA from different sources37
635564920Restriction EnzymeAn enzyme that cuts DNA at a specific sequence of nucleotides38
635564921BacteriophageA kind of virus that infects bacteria. "bacteria eater"39
635564922Missense mutationA point mutation in which a single nucleotide is changed, resulting in a different codon that codes for a different amino acid40
635564923Nonsense mutationA point mutation that results in a premature stop codon41
635564924LigaseAn enzyme that repairs places where the DNA is broken42
635564925Complementary strandA strand of DNA or RNA that has complementary bases to another strand of DNA or RNA. For instance, during DNA replication, the new strand that is formed is a complementary strand. (Complementary bases: A-T, C-G)43
635564926RNA polymeraseThe enzyme that separates and copies the DNA strand to make a complementary RNA strand.44
635564927HelicaseThe enzyme that splits the two strands for DNA replication45
635564928DNA replication1. Helicase unzips the double helix 2. DNA polymerase uses one strand to copy the information to produce another complementary strand 3. DNA polymerase connects individual nucleotides to their corresponding bases to connect the DNA molecule 4. DNA polymerase proof-reads the DNA46
635564929Transcription1. RNA polymerase splits a DNA double helix at a point called a promoter (AUG) 2. RNA polymerase uses one strand as a template to make a complementary mRNA strand47
635564930Translation1. An mRNA molecule in the cytoplasm attaches to a ribosome 2. The proper amino acid is brought into the ribosome by a tRNA (proper=tRNA that matches the codon on the mRNA) 3. In the ribosome connects the amino acids from the tRNA to each other, using rRNA. Ribosome forms a peptide bond between the amino acids and breaks the bond that had held the amino acid to the tRNA. It continues this until it reaches a stop codon, where the polypeptide (or protein) and mRNA is released48
635564931Restriction enzymeEnzymes that cut DNA at a specific sequence of nucleotides49
635564932Recombinant DNADNA molecules that are produced by combining DNA from different sources50
635564933TransformationAny change in an organism that alters its general character and mode of life51
635564934Genetic engineeringMaking changes directly to the DNA molecule52
635564935CloneA member of a population of genetically identical cells produced from a single cell53

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