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Biotechnology Flashcards

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15740183062BiotechnologyAny technology that uses living organism or substances from those organisms in agriculture, industry, or medicine (farming)0
15740211082What are the 4 organic molecules?Carbohydrates Lipids Proteins Nucleic acids1
15740216437Why are they called organic molecules?They have a carbon base2
15740218859What type of organic molecule is an enzyme?Protein3
15740221779Which 2 of the 4 types of organic molecules are involved in genetics?Proteins Nucleic acids4
15740223991What are the 2 types of Nucleic Acids?DNA (deoxyribonucleic acid) RNA (ribonucleic acid)5
15815156483What is a "Genome"?All the DNA in one cell of an organism6
15815163845What is a "Chromosome"?DNA divided into chunks7
15815171287What is a "Gene"?A section of DNA8
15815202124How many genomes do humans have?3 billion base pairs9
15815209609How many chromosomes do humans have?46 (23 pairs)10
15815217472How many genes do humans have?20,00011
15815366367What are the 3 parts of a genePromoter Coding region Termination sequence12
15815220053PromoterRegion where RNA polymerase attaches (attaches to nucleotide) and initiates transcription13
15815378914Coding regionWhere RNA polymerase makes mRNA14
15815394994Termination sequenceRNA polymerase releases from the DNA (end)15
15815408288Chromosomes come in...Matching pairs (Homologous Pairs)16
15815418706Where did each member of the pair come from?From the parents17
15815467918What does "XX" represent?Female18
15815472397What does "XY" represent?Male19
15815482070Chromosome theory of inheritance"The two members of each homologous pair of chromosomes carry alleles for the same gene and therefore affect the same trait" - Walter Sutton 190320
158155091412 alleles that are identical are...Homozygous21
158155212162 alleles that are different are...Heterozygous22
15815601789How many copies (Alleles) are there for every gene?Two23
15815644458The most common allele is known as the "Wild-Type", also known as...Dominant allele (WT)24
15815648740SNPSingle nucleotide polymorphism25
16104832627Gene codes for...Protein26
16104832628What's the order of Gene AddressChromosome Arm Region Band27
16104832629NucleotidesBuilding blocks of DNA28
16104832630SequenceOrder of DNA29
16104832631DNA is made up of how many different nucleotides? What are they called?Adenine Thymine Cytosine Guanine (4)30
16104832632What are the 3 parts of a nucleotide?Phosphate group Sugar Base31
16104832633What are the 5 elements make up a nucleotide?Carbon Hydrogen Oxygen Nitrogen Phosphorus Sulfur (sometimes)32
16105264734What is the function of "Globin" Genes?Contain instructions for making hemoglobin protein, which allows our blood to carry oxygen throughout the body33
16105294350The phosphate group is attached to...The 5th carbon of the sugar34
16105358601A hydrogen or a hydroxide is attached to...The 2nd carbon of sugar35
16105384161What is the function of the 3rd carbon of sugarUsed to attach the phosphate group of the next nucleotide in the sequence36
16105406905Which carbon of sugar is the base attached to?Attached to the 1st carbon37
16105429415What are the backbones of DNA called? (sides of the ladder)Sugar Phosphate38
16134523289What are Purines?Adanine Guanine39
16134524537What are Pyrimidines?Cytosine Thymine Uracil40
16134624669Examples of PrionsMad Cow Disease Kuru CJD Scrapies41
16134653172MutationPhysical change caused by a change in DNA42
16134592827How many amino acids are used by every human organism?2043
16134728973eRNAEnhancer RNA, activates transcription44
16134613010Proteins are made up of...Amino acid chains45
16134618209What determines the primary structure?DNA46
16134651922What is the protein that is made by the Lac OperonLactase47
16134635110What makes cells different?Which genes are turned off or on (how genes are expressed)48
16134680544Steps to repair after a lesion is foundEnzyme (1) separates the 2 strands of DNA Enzyme (2) removes misplaced or damaged nucleotide Enzyme (3) DNA polymerase fills the gap with the correct nucleotide using the template from the other strand49
16134638669How do we know if a gene is expressed?It makes a protein and can make RNA50
16134687977What does spliceosome do?Splices intron from mRNA51
16134652526VariantChange in DNA52
16134698631Can the 2 alleles be the same? Can they be different? What are the names of the allele pairings?Yes, homozygous and heterozygous53
16134588804Where did the information to make tRNA come from?mRNA54
16134528093Why are the rungs (steps of the ladder) held together with weak hydrogen bonds?Easier to split side-to-side instead of halves55
16134667995SNPs (snips)Single Nucleotide Polymorphisms Change at one nucleotide position, can be a single nucleotide mutation if it changes the amino acid coded by the gene56
16134629075If the hydrogen bonds break in a protein, what will happen?It will denature (fall apart)57
16134554648What is the difference between DNA and RNADNA: Double stranded Missing one oxygen (uses deoxyribose as sugar) Has Thymine Found in nucleus (location) RNA: Single stranded Has all oxygen (uses ribose as sugar) Has Uracil Found in nucleus and cytoplasm (location)58
16134608396What are the names of the proteins called?Carbon Hydrogen Oxygen Nitrogen Sulfur (sometimes)59
16134600017Who won the Nobel Prize for RNAiAndrew Z. Fire Craig C. Mello60
16134566761Is an enzyme a folded amino acid chain?Yes61
16134713647(Rr) The dominant trait is expressed but the protein level is less, why?Due to one of the genes are making the proteins62
16134666674TransposonsJumping genes63
16134586309Where did the information to make ribosomal RNA come from?DNA64
16134630859What are the 2 most common causes of denaturing (breaking of hydrogen bonds) in a protein?Increase temperature Change in pH65
16134649100Why is Lac Operon important?First experiment to show genes can be turned off and on66
16134644387Can genes be switched on and off?Yes67
16134532356Which DNA nucleotide always pair up in the the middle of the ladder?A-T C-G68
16134609974What are proteins used for?Muscles, hormones and enzymes69
16134578849How many genes are in humans?20,00070
16134694603One allele for each gene is inherited from each parent, what does that mean?You inherit a version of a gene71
16134580118How many chromosome pairs do humans have?23 (46 chromosomes)72
16134691968AlleleParticular sequence of DNA73
16134650523Quiescent geneQuiet gene74
16134583891Where do amino acids come from?Food & floats around the cytoplasm75
16134578380How many base pairs are in humans?3 billion76
16134597131Gene therapy can be used for...Huntington disease77
16134708278How is heterozygous be shown in basic Mendelian genetics?Aa78
16134582986Who won the Nobel Prize for DNA transcription?Roger Kornberg79
16134627480What's the function of hemoglobin?Carries oxygen in red blood cells80
16134686518What the function of DNA ligase?Links the sugar-phosphate backbone together81
16134677522Neutral MutationMutation with no known function82
16134645058OperonCombination of protein-coding DNA sequence and the regulatory sequence83
16134607841T/F: Proteins are very complexTrue84
16134656138What are examples of mutation?Whole Chromosomes Transposons SNPs Neutral Mutation85
16134542001What are the DNA properties?DNA encodes information Controls synthesis of protein and RNA, function of the cell Stores instructions to be passed onto the next generation DNA changes by mutation DNA makes copies of itself86
16134549520HelicaseAn enzyme that unzips DNA87
16134563615ProteinA folded amino acid chain88
16134632622What are examples of denaturing?Bacteria and viral death by sterilization and disinfectants Tenderizing meat Change in color and texture of fried egg whites89
16134696681How many alleles for a gene does one individual have? Why?2 sets of chromosomes, come from each parent90
16134587034Where did the information to make mRNA come from?DNA91
16134636883All cells in one individual have the same DNA, how did this happen?Started from one cell, mitosis92
16134657669Whole ChromosomesFailure in an egg or sperm that results an abnormal increase or decrease of chromosomes93
16134620284PrionsPart of the nervous system, once they come in contact with a misfolded prion protein they change their folding94
16134707011How is homozygous be shown in basic Mendelian genetics?aa or AA95
16134627062How many chains are in the hemoglobin?496
16134652527PolymorphismCommon variation97
16134643769How could Gene Expression happen?Different cells and different genes are turned on98
16134664514KarotypeA picture of chromosomes lined up in order (biggest to smallest) Spots extra or missing chromosomes99
16134617428What is removed when a peptide bond is formed?Water100
16134723268Protein Synthesis is also called...Central Dogma101
16134724687T/F: Protein synthesis does require DNA replicationFalse102
16134551552DNA polymeraseAn enzyme that makes DNA103
16134589930Where did the information to make any RNA come from?eRNA104
16141804614Steps for DNA replicationDNA unzips and rebuilds other side one nucleotide at a time (creating a new strand) Starts at the 5' (carbon) end of the template strand Enzyme unzips (helicase) Rebuilds DNA (DNA polymerase)105
16141967724IntronsSequence of DNA that is not involved in coding for a protein ("intruders")106
16141961548The disorder "Muscular Dystrophy" is a result of...?An intron splicing error (wrong protein or no protein is made)107
16141965491ExonsExpressed sequence of DNA; codes for a protein ("extra special")108
16142570922Diploid2 sets of chromosomes109
16142598012What is an example of a DNA mutation that effects Transcription?Methylation110
16142570290Haploidsingle set of unpaired chromosomes111
16142678762Our cells contain an _____ that cuts up double stranded RNA.Enzyme Dicer112
16141951552When splicing an Intron, what can it result?Exome113
16142670821What does RNAi do?Blocks translation by attaching to mRNA and destroying the mRNA114
16141911169What are the steps of "Transcription"?RNA polymerase binds to the promoter, signals DNA to unzips, separates strands for a template RNA polymerase reads unzipped DNA strand & builds mRNA to make a RNA chain growing 5' to 3', RNA is formed & leaves DNA Transcript is finished (terminated)115
16141930956RNA EditingRemoving introns and putting exons together in mRNA after leaving the DNA116
16141797528What is DNA replication used for?Mitosis or Meiosis, not for protein synthesis117
16142664043What was DNA methylation used for?Estimating age, forming an accurate biological clock in humans & chimpanzees118
16142025005Steps of TranslationAfter transcription, mRNA carries instructions in codons for building polypeptides The edited mRNA moves to a ribosome to meet the tRNA tRNA binds to matching codon119
16141940974How are Introns removed?By a spliceosome (splicing)120
16141848572What is DNA transcribed into?mRNA by RNA polymerase121
16141841020TranscriptionCollecting information to make one protein out of the nucleus (making DNA into RNA - 1st step of protein synthesis)122
16142684102Amino acids are joined together by...?Dehydration synthesis (by removing the water, the amino acids are able to stick together123
16142637605What does DNA methylation do?Physically prevent the binding of the proteins to the gene124
16142601657What is Methylation? What is happening throughout the mutation?When C (Cytosine) is next to G (Guanine) can mutate and become a T (Thymine) which changes the code A cluster of Cs next to Gs is often in the promoter region of the genes and when the Cs are altered, the RNA polymerase cannot attach and the gene can't be transcribed125
16142667787What are ribosomes made of?RNA126
16142941847DNAdeoxyribonucleic acid127
16142941848RNAribonucleic acid128
16143342949Polypeptidechain of amino acids129
16148724156What are the structures in "Amino Acid"? Where are the structures located?Animo group (left side) Hydrogen (located on top) Carbon (center) R - R group variant (bottom) Carboxyl (right side)130
16148481804Primary structureSequence of amino acids (stretched)131
16148617459What happens during "Dehydration Synthesis"?Amino acids are joined together with peptide bonds that are always connecting the amino group of one to the carboxyl group of the next in a chain (polypeptide) & water is removed. Once the water is removed, the chain folds up and creates a protein132
16148385165Who won the Nobel Prize for DNA structureWatson, Crick, and Wilkins133
16148433149Punnet SquaresDiagram showing the gene combinations that might result from a genetic cross EX: DDxdd, DdxDd, DDxDD, ddxdd134
16148493444Secondary structureThe second level of protein structure; the regular local patterns of coils or folds of a polypeptide chain. (twisted)135
16148526362Teritary structureThe complex 3-dimensional structure of a single peptide chain; the structure at which polypeptide chains become functional (bundled chains)136
16148506108What are the levels of Protein structures?Primary structure Secondary structure Tertiary structure Quaternary structure137
16148558222Quaternary structureThe fourth level of protein structure; the shape resulting from the association of two or more polypeptide subunits.138

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