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Brain and Behavior Exam 1 Flashcards

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2911500809Describe the similarities and differences between the human brain and brains of other speciesSimilarities: brain areas, chemicals, proteins Differences: Overall brain size, size of individual parts (large neocortex in primates)0
2911505226What is gray matter?Nucleus in the CNS and Ganglion in the PNS1
2911505227What is white matter?Tract in the CNS and Nerve in the PNS Appear white because of mylenation2
2916086209What is the somatic nervous system?Movements that you are aware of and are consciously making3
2916087824What is the Autonomic Nervous System?The processes that your body controls for you4
2916093111What are afferent nerves?Sensory neurons going TOWARDS the brain5
2916099244What are efferent nerves?Neurons sending messages AWAY from the brain6
2916107718Where are the sympathetic and parasympathetic nervous systems located and what are their functions?Located in the efferent nerves of the ANS Symp: Arousal Para: Calming7
2911507621What are the three primary divisions of the brain and what major structures are in those divisions?1) Hindbrain - 2)Midbrain - 3)Forebrain -8
2911511597What 3 structures comprise the brain stem?1) Medulla 2) Pons 3) Midbrain9
2911514866What major functions is the medulla involved with?Base of the brain stem Contrals vital reflexes Control via cranial nerves Damage to medulla can cause coma or death10
2911517677What major functions is the pons involved with?Middle of the brainstem (lump) Sleep11
2911518934What major functions is the cerebellum involved with?Movement Well-learned movements Sensory timing Balance and postural control12
2911519969What major functions is the midbrain involved with?Top portion of the brainstem (right above pons) Reflexive orienting to visual and auditory stimuli Intrinsic/descending pain control Substantia nigra located here13
2911522707What are the structures within the midbrain? Functions?Substantia Nigra14
2911523841What major functions is the thalamus involved with?Relay station/filter for sensory information on its way to cortex Involved in many other systems15
2911523842What major functions is the hypothalamus involved with?Communicates with pituitary gland to alter hormone release Involved in drive-related behaviors and maintenance of homeostasis16
2911526921What major functions is the pituitary gland involved with?Endocrine gland Attached to hypothalamus by pituitary stalk Makes and releases hormones into bloodstream17
2911527005What major functions is the pineal gland involved with?Makes and secretes melatonin Daily and seasonal rhythms18
2911529726What major functions is the corpus collosum involved with?Largest hemisphere-connecting tract19
2911533681What major functions is the longitudinal fissure involved with?A groove that separates right and left hemispheres20
2911539076What is the function of the telencephalon?Largest division of the brain and it subserves language (aspects of language which are of interest to linguistics) Consists of basal ganglia, cerebral cortex, and olfactory bulb Anterior part of the brain21
2911541464What is the function of the diencephalon?Above the brain stem and embodies the thalamus and hypothalamus22
2911543565What is the general function of cranial nerves?Enter/exit the ventral surface of the brainstem and are important in neurological exams Information comes in through these nerves and eventually ends up in the sensory cortex23
2911547324What does "sensory and motor for face and head" mean?Cranial Nerves allow facial expression and jaw movement Damage to connections from cortex to brains stem contralaterally damage and weaken muscles of the lower portion of the face24
2916016447Describe a motor neuronThe cell body lives in the spinal cord and the axon is part of a nerve in your body The terminal synapse with muscle fibers25
2916025180Describe a somatosensory neuron?Touch neuron The soma lives outside of the spinal cord and has a long axon that has specialized endings in the skin and its terminals are in the spinal cord26
2911551186How many cranial nerves are there?12 pairs (24 nerves)27
2911554142What is the general function of the limbic system?Memory and emotion Regulation of motivated behaviors Hippocampus, amygdala, etc located here28
2911554143What is the general function of the basal ganglia?Movement Interconnected structures: striatum, globus pallidus, and substantia nigra29
2916213810The lobes of the Cortex1) Frontal 2) Parietal 3) Temporal 4) Occiptal30
2916217991Function of the Occipital lobeVision Primary and secondary visual cortex31
2916221023Function of the Frontal LobePrefrontal cortex: executive functions Planning, working memory, insight, impulse control, last to develop32
2916229048What structure is located within the frontal lobe?Motor Cortex: Voluntary movement, somatotopic organization, cerebellum and basal ganglia influence movement talking to motor cortex33
2916238582Function of the Parietal Lobe and what structure is located hereSomatosensory Corex: first cortex to process somatosensory info and somatotopic organization Spatial Organization Visual association corrtex34
2916254022Temporal LobeAuditory Cortex - hearing Spoken Language comprehension Visual Association cortex35
2916236607What area of the frontal lobe is important for language?Broca's area36
2911559035What are the 2 major structures of the limbic system?Hippocampus and Amygdala37
2911561742What structures comprise the Central Nervous System?Brain and spinal cord38
2911564141What structures comprise the Peripheral Nervous System?Somatic Nervous System and Autonomic Nervous System39
2911566463How is the Peripheral Nervous System divided?SNS and ANS ANS --> Sympathetic and Parasympathetic NS40
2914913568All behavior, both normal and abnormal, including perceptions, thoughts, movements, and complex social behaviors, are correlated with...brain and nervous system activity41
2914917870Define and discuss the field of biopsychologyThe scientific study of the biology of behavior42
2914920174Describe six areas of neuroscience that are particularly relevant to biopsychological injuryNeuroanatomy - structure of the nervous system Neurophysiology - Functions and activities of the nervous system Neurochemistry - chemical bases of neural activity Neuropathology - nervous system disorders Neuropharmacology - Effects of drugs on neural activity Neuroendocrinology - Interactions between the nervous system and the endocrine system43
2914924641What are the advantages of humans and nonhumans as subject in biopsychological research?Humans: can follow instructions, make subjective reports, and are cheaper to work with Nonhumans: simpler brains, comparative approach, ethical reasons44
2914924642What are the disadvantages of humans and nonhumans as subject in biopsychological research?Humans: Ethical limitations, complex brain Nonhumans: only can get a comparison to the human brain, no subjective reports45
2914973121True experiments are not always possible. Why and give examples?Ethics, costs, etc Ex: We don't/can't assign some people to smoke cigarettes and others not to, We can't subject some participants to a disease, etc46
2914981867What are converging operations? Give examplesMultiple approaches; strengths of some compensate for the weaknesses of others Ex: Epidemiological studies in humans, Exposure and toxicity studies in animal models (not in humans but allows experimentation)47
2914992100What is preponderance of the evidence? Give examplesThe majority of the evidence points to a single answer Ex: Smoking cigarettes correlated with lung cancer, longer someone smokes --> more likely to get lung cancer, exposure to smoke in non-smokers --> increased rick of lung cancer48
2914929082Explain how converging operations contributed to the study of Korsakoff's syndromeKorsakoff's Syndrome: severe retrograde amnesia and confabulation, but intelligences in tact (often seen in severe alcoholism) We don't assign some people to have poor diet, and some people to be alcoholics. We do however see, that the syndrome typically is a result of poor nutrition and is exacerbated by alcohol The above correlation was seen in rats49
2914930815What are the four major themes of our approach to Biopsychology1) Thinking (critically and) Creatively about Biopsychology 2) Clinical Implications 3) The Evolutionary Perspective 4) Neuroplasticity50
2915026129Describe what is meant by the major theme "Thinking Creatively about Biopsychology"Base thinking on the evidence presented Consider physiology, development, evolutionary history, emotional state, current circumstances, experience, function, etc Consider the source of your information51
2915036234Describe what is meant by the major theme "Clinical Implications" of biopsychologyThe study of diseased or damaged brains leads to new knowledge; new knowledge leads to new treatments52
2915043598Explain the parts of Psychological research (basic, applied, translational)Basic - Conducted for the purpose of acquiring knowledge (basic research programs) Applied - Intended to bring about direct benefit to humankind, animal studies Translational - Direct steps taken in practical application (ex: human drug trials)53
2915056747Describe what the major theme "The evolutionary perspective" in biopsychology meansConsideration of environmental pressures on human evolution May use a comparative approach54
2915062544Describe what the major theme "Neuroplasticity" in biopsychology meansThe brain is plastic, not static The brain is constantly strengthening connections between neurons55
2914935741Explain and discuss why thinking about the biology of behavior in terms of a traditional physiological-psychological dichotomy is flawedBehavior is not physiological or psychological What is psychological IS physiological56
2914938706What is the mind-brain connection and describe examples?Dualism vs. monism monism - "the mind is what the brain does" What effects the brain, effects the mind Ex: HM had his hippocampus removed and could not make new memories Ex: Removing one hemisphere of the brain effects contralateral processing Ex: Blindsight, throwing a ball to someone blind and them still being able to catch it or know where it is going57
2915087297How does stimulation of brain activity effect the mind-brain connection?Evokes experiences or behavioral tendencies Drugs of abuse stimulate certain brain regions and reinforce behaviors58
2915118105Experiments vs. NonexperimentsExperiment: involves the manipulation of variables and CAUSAL relations can be drawn Nonexperiment: researcher does not control the variables of interest and ASSOCIATIONS can be drawn59
2915124990Quasiexperimental studiesStudies of groups of subjects exposed to conditions in the real world60
2915127212Case StudiesFocus is on a single individual Often test a hypothesis, not necessarily generalizable61
2915132597Define what is meant by a Causal RelationRequires more rigorous science Variables must be manipulated and systematically tested against a control group (you cannot just measure variables) Correlation does not imply causation Generalizability is also an important factor to consider62
2915144108Describe Darwin's evidence for evolutionPresented 3 kinds of evidence for species' evolution, and argued that evolution occurs through natural selection 1) Fossil Evidence of evolution 2) Structural similarities among living species suggest common ancestors 3)Impact of selective breeding63
2915182247What is natural selection?The idea that heritable traits that are associated with high rates of survival and reproduction are preferentially passed on to future generations64
2915187160Why did Darwin prefer the term "decent with modification" to "evolution"?Evolution denotes a change that will always be better than what came previously. As the environment changes, however, preferred traits will also change. Thus a trait is advantageous to an individual at one time, might be detrimental at another time if the environment has changed.65
2915187161In what ways has the human brain evolved?1) The human brain has increased in size during evolution 2) Most of the increase in size has occurred in the cerebrum 3) Increased convolutions (folds in cortex) = increase the volume of the cerebral cortex66
2915237848Most human phenomena (facial expressions, intelligence, sexual orientation, etc) are based in part of...genetics67
2915242813What are chromosomes, what types exist within humans, and how many are there?22 paired chromosomes (46 chromosomes total 2 sex chromosomes located in the nucleus of the cell and contain DNA68
2915254030What does the sequence of DNA determine?The gene69
2915255767What is a gene?Contains information on hereditary characteristics70
2915257830What is a phenotype?An observable trait Ex: Hair color, eye color, height, susceptibility to certain disease71
2915245706What is a karyotype?the number and appearance of the chromosomes72
2915251047What is a genotype?The genes you have for a trait Ex: BB, ww, Bw73
2915265238What are alleles?Two genes that control the same trait74
2915268254Homozygous vs. Heterozygous allelesHomo: identical alleles for a trait Hetero: different alleles for a trait75
2915273619What is meant by gene dominance?A gene that shows a strong effect in the heterozygous or homozygous condition76
2915275618What is meant by a gene being recessive?A gene that shows a strong effect only in the homozygous condition77
2915282365What are sex-linked genes and where are they typically located?The genes on the sex chromosomes and are usually found on the X because it has a lot more genes on it than the Y78
2915288952What are sex-limited genes and where are they located?Present in both sexes but has an effect only (mostly) in one sex Ex: genes for chest hair and genes for breast size They are on autosomal chromosomes and are "turned on" under influence of sex hormones79
2915295607Describe the structure of DNADouble stranded Four base pairs Self-replicating80
2915189552Outline the mechanisms of gene expression1) Strands of DNA unravel 2) A copy is made (messenger RNA) through transcription 3) Protein is built based on code of mRNA through process of translation81
2915314632Define TranscriptionA strand of RNA is copied from one of the strands of exposed DNA --> RNA goes to cytoplasm DNA-->RNA82
2915317532Define TranslationMessenger RNA attaches to a ribosome --> ribosome reads each codon and attaches appropriate amino acid RNA-->Protein83
2915323556What is a codon?3 base pairs which code for an amino acid84
2915330021How many meters of DNA are in a cell? In a person?2 meters per cell 100 trillion m per person85
2915333219What is chromatin?Condensed DNA coiled around a core of histone proteins86
2915339147What does the structure of coiled DNA have strong implications for?gene expression To express a gene, the coil where the gene is located needs to be loosened (by chemical groups - methyl/acetyl)87
2915191146Describe the difference between genetics and epigeneticsGenetics: the genes we get from our parents Epigenetics: alterations that can occur to our genes based on experience, and they can be heritable88
2915369701What are especially powerful experiences that may influence epigenetics?prenatal and neonatal experiences89
2915192225What are the two main epigenetic changes that can occur? Describe each1) Histone Remodeling - modifications to a histone protein (around which DNA is coiled) can either decrease or increase gene expression 2) DNA methylation - the attachment of a methyl group to DNA tends to reduce the expression of adjacent genes90
2915195590Describe 3 classic examples of research on behavioral development and how each illustrates gene-experience interaction1) Selective Breeding of "maze-bright" and "maze dull" rats 2) Phenylketonuria (PKU): a single-gene metabolic disorder 3) Development of birdsong91
2915196999Explain heritability estimatesHow much of the variance in a characteristic is due to differences in heredity (genes) Contribution of genetic differences to phenotypic differences92
2915382659How could genes affect behaviors?Altering neurotransmitter systems and other chemicals, thus how an individual processes info, perceives stimuli, and responds to the environment Altering physical appearance and thus how the environment responds to the individual93
2915394341How do we know about heritability of behavior?Biochem methods: identification of certain genes linked to behaviors or disorders Twin and adoption studies94
2915203162Describe the twin studies discussed in class. What were their strengths weaknesses, and what they tell us about the interaction of genes and experience?MZ and DZ twins 1) Greater concordance in MZ twins than DZ twins --> the more DNA 2 individuals share, the more likely they are to share a trait Suggests high heritability 2) Same concordance in MZ twins and DZ twins --> amount of shared DNA doesn't impact likelihood of sharing trait Suggest low heritability95
2915418632Twins Reared Apart59 pairs of MZ twins 47 pairs of DZ twins Extensive intelligence and personality testing Adult MZ twins more similar on all measures than adult DZ twins96
2915429908What is meant by the term "virtual twins"?Children of the same age, with no relation to each other, adopted into a home at the same time97
2915437039What are the problems with twin studies?MZ twins usually share chorion and blood supply...so could be genetics or could be prenatal environment The studies assume that DZ twins are treated as similarly as MZ twins98
2915445405What are the problems with adoption studies?Biological children tend to have similar mental problems to biological parents even if raised by "great" adoptive parents...could be genes, BUT could be reflection of poor prenatal environment99
2915461865What have we learned from twin studies of the effect of experience on heritability?1) Intelligence develops as an interaction of inheritance and experience 2) Can inherit potential for superior intelligence, but might not be realized in poverty-stricken environment100
2915474980What is the interaction of genetic factors and experience on behavioral development?Ex: Raised maze-dull and maze-bright rats (impoverished areas --> more mistakes) Ex: PKU Disorder (mitigated entirely by a special diet during critical development period --> interaction between genetics and environment101
2915497157Define ConcordanceThe presence of the same trait in both individuals of a pair of twins102
2915500436What is an autosomal chromosome?Chromosomes that come in matched pairs In mammals, these are all of the chromosomes except the sex chromosomes103
2915502647What are nucleotide bases and how are they paired?A class of chemical substances that includes adenine, thymine, guanine, cytosine - the constituents of the genetic code A-->T C--> G104
2915508136What are proteins?15% of body mass Some become part of the body's structure and others are enzymes that control the rate of chemical reactions105
2915617542What are neurons?Specialized cells for the reception, conduction, and transmission of electrochemical signals Basic units of the nervous system106
2915626151What are the similarities between neurons and other cells in the body?Organelles, including plasma membrane, ER, nucleus, mitochondria, cytoplasm, ribosomes, Golgi complex, vesicles, microtubules107
2915648641What is a cell nucleus?A structure in the central region of a cell, containing the nucleolus and chromosomes108
2915655013What is the nucleolus?A structure within the nucleus of a cell that produces the ribosomes109
2915657532What is a neurotransmitter?A chemical that is released by a terminal button; has excitatory or inhibitory effect on another neuron110
2915663525What is a cells mitochondrion?An organelle that is responsible for extracting energy from nutrients111
2915666475What is ATP?A molecule of prime importance to cellular energy metabolism; its breakdown liberates energy112
2915673670What is the Endoplasmic Reticulum?Parallel layers of membrane found within the cytoplasm of a cell Two types: smooth and rough ER Smooth: site of sysnthesis of lipids and provides channels for the segregation of molecules Rough: contains ribosomes and involved with production of proteins113
2915685901What is the Golgi apparatus?A complex of parallel membranes in the cytoplasm that wraps the products of a secretory cell114
2915693222What is the cell membrane and what is its function?A phospholipid bilayer with signaling proteins and channel proteins embedded in it that is semipermeable to let water, oxygen, and CO2 move freely Na+, CA2+, K+, Cl- move thru ion channels115
2915630000What are the differences between neurons and other cells in the body?Morphology Communication with each other, often very long distances Postmitotic116
2915638277Define the term "postmitotic"Cells that are no longer dividing Once they have gone where they are going to stay in the brain, with their distinct shapes, they do not divide any longer117
2915601027Compare and contrast multipolar, bipolar, and unipolar neuronsMultipolar: Cell body with dendrites and an axon (majority of the brain's neurons) Bipolar: Long axon with cell body with in the middle and two axons branching from opposite sides Unipolar: Long axon that bifurcates at a cell body (cell body is not attached to axon from two sides)118
2915602476Identify the parts of a synapse1) Synapse, Synaptic Cleft, Synaptic Gap - space between the terminal and dendrites of two neurons where chemicals cross 2) Presynaptic - conducts action potential from soma to terminal 3) Postsynaptic - neuron that is receiving chemicals119
2915605067Describe the techniques used to visualize neurons1) Electron Microscopy - microscope that produces an electronically magnified image of a specimen for observation 2) Golgi Stain - heavy metal stain penetrates and fills a subpopulation of neurons 3) Nissl Stain - Stains all cell bodies, but you cannot see the entire morphology of the neuron (good indication of neural density) 4) Fluorescence microscopy - Certain things are amplified with a fluorescent tag 5) Tracing Studies - Tracing to and from where axons project from120
2915608094Briefly describe 6 kinds of glial cells and their functions in the nervous system1) Cell Body - "Soma" contains all of the organelles of the cell 2) Dendrites - Receiving ends of neurons that receive signals from other neurons 3)Axon - Myelinated channel through which the action potential travels, microtubules inside for transmission of information 4) Terminal Buttons - End of the axon that stores and releases neurotransmitters 5) Axon Hillock - first part of axon that decides if the action potential will be passed on or not 6)Synapse - Space between the terminal button and dendrite of two neurons, where neurotransmitters are released121
2915825056What is the "new" definition of nucleus? And how is this related to neurological diseases?A group of neurons with a common location, common connections, and common functions Many neurological diseases are due to loss of a group of neurons (nucleus)122
2915837767What are glial cells and what do they do?Support neurons by means of communication by changing the way that neurons function123
2915844810What type of Glial cells are Schwann and Oligodendrocytes?Myelinated glial cells Schwann - myelinates PNS Oligo - myelinate CNS124
2915853886What type of glial cells are Microglia?Search for and respond to injury or disease Multiply, engulf cellular debris, trigger inflammatory response125
2915867836What type of glial cells are satellite cells?Surround cell bodies of neurons in the PNS126
2915871864What type of glial cells are ependymal cells?In the walls of the ventricles and help make cerebrospinal fluid Help nurture and support the stem cells that are in the brain127
2915878810What type of glial cells are astrocytes?Wrap around terminal of related axons, remove waste material, provide structural support, form dense scars upon injury, dialate blood vessels in active regions of the brain, provide nutrients from blood to neurons, BBB128
2915610300Describe the structure and function of the blood brain barrierA barrier around blood vessels in the brain that protect neurons from all the chemicals/toxins that we cannot flood neurons with129
2915895398What are endothelial cells?Cells of capillary walls that form tight junctions but are made of a thin layer of cells Surrounded by astrocytes130
2915901431BBB keeps out:Viruses and bacteria Many chemical and nutrients131
2915905651BBB lets through:Small uncharged molecules Fat-soluble molecules Glucose L-Dopa Some viruses (ex: chicken pox, herpes)132
2915610301Describe the incomplete regions of the BBBThese are called Circumbentricular organs and they are important for the brain to sense toxins in the blood that need to be removed133
2915960814What are the contributions of Camillo Golgi to our understanding of neurons?Revolutionary method of staining individual nerve and cell structures by using silver nitrate134
2915965587What are the contributions of Santiago Ramon y Cajal to our understanding of neurons?Fine structure of NS and especially of brain and spinal cord135
2915988108What causes the onset of Parkinson's Disease?Loss of substantia nigra in midbrain136
2916001379What causes the onset of Huntington's Disease?Loss of caudate and putamen in forebrain137
2916004550What causes the onset of ALS?Loss of motor neurons in cerebral cortex and spinal cord138

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