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Cambell's Biology Chapter 17 Flashcards

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1946193152GeneA discrete unite of hereditary information consisting of a specific nucleotide sequence in DNA0
1946193153DNAA double-stranded, helical nucleic acid molecule, consisting of nucleotide monomers with a deoxyribose sugar and the nitrogen bases (A,T,C,G)1
1946193154Nucleotide DifferencesRNA is a single strand, ribose sugar and U with A, not T. DNA is double stranded, deoxyribose and T, A, C, G.2
1946193155RNA Modifications after transcriptionImmature RNA becomes mature due to protein splicing3
1946193156mRNA____in the nucleus that encodes the DNA code, writes it down, has U's instead of T's, only one strand4
1946193157RNA PolymeraseAn enzyme that produces primary transcript RNA by attaching to the promoter region of the DNA, after it's unwound(by helicase).5
1946193158poly(A) TailA sequence of 50 to 250 adenine nucleotides added onto the 3' end of a pre-mRNA molecule6
19461931595' Capspecially altered nucleotide on the__end of some eukaryotic primary transcripts -guanine cap which serves to protect the RNA and attach the ribosomes.7
1946193160TranslationWhen mRNA and tRNA(anticodon) translate the code, by transferring the correct amino acid for the codon(mRNA) There is a change of "language" from nucleotides to amino acids8
1946193161Protein Synthesisthe process by which amino acids are linearly arranged into proteins by mRNA writing down the code from the DNA template, tRNA transferring the correct amino acid, and then they bond to form the protein.9
1946193162Ribosome (large vs small)A molecule consisting of 2 subunits that fit together and work as 1 to build proteins according to messages in mRNA. Using mRNA as a template, it traverses codon and pairs with the right amino acid. Interacting with tRNA.10
1946193163A siteribosome binding site. holds tRNA carrying amino acid for polypeptide chain11
1946193164tRNATransports specific amino acids to ribosome to add to polypeptide chain on the ribosome12
1946193165rRNAlocation where the mRNA and tRNA meet; 2 units(lg and sm)13
1946193166Start CodonThe first of the 3 nucleotide sequence that specifies, AUG, that establishes the reading frame for protein synthesis14
1946193167Aminoacyl-tRNA synthesaseAn enzyme that joins each amino acid or the to the appropriate tRNA15
1946193168Amino acidsAn organic molecule possessing both carboxyl and amino groups. They serve as the monomers of polypeptides to build a protein16
1946193169Peptidyl Transferasean enzyme that catalyzes the addition of amino acid residues to the growing polypeptide chain in protein synthesis by means of peptide bonds17
1946193170Polypeptidesingle linear chain of many amino acids, held together by amide bonds18
1946193171Codonsa sequence of three DNA or RNA nucleotides that corresponds with a specific amino acid or stop signal during protein synthesis19
1946193172Stop Codonsnucleotide triplet within messenger RNA that signals a termination of translation. UGA, UAG, UAA20
1946193173Anticodonsa sequence of three nucleotides in a region of transfer RNA that recognizes a complementary coding triplet of nucleotides in messenger RNA during translation21
1946193174Initiation...1st step in translation of RNA. Two step process to establish exactly where translation will begin, ensuring that the mRNA codons are translated in the correct sequence of amino acids.22
1946193175Elongation...Aminoacyl tRNA brings a new amino acid to the A site. And the binding occurs due to cod an/anticodon recognition23
1946193176Termination...tells the polymerase to stop by Release Factors which bind with stop codons in the A site; add water to release the chain from final tRNA, mRNA is released and free24
1946193177promoterDNA sequence where RNA polymerase attaches and initiates transcription, contains the TATA box25
1946193178TATA boxa promoter DNA sequence26
1946193179direction for processing mRNADNA-3 to 5, mRNA-5 to 327
1946193180transcription factorsproteins that mediate the binding of RNA polymerase28
1946193181RNA splicingremoval of large portions of RNA molecule that is initially synthesized-long noncoding sequences, not continuous(split into segments)29
1946193182intronsintervening sequences that do not code-stay in the nucleus, refer to both the DNA and RNA sequences that encode them30
1946193183exonsEXIT the nucleus, because they will be coded31
1946193184wobblepairing with tRNA -can be different anticodons synonymous for a given amino acid; allows 45 rRNA molecules to service all the different types of codons on the mRNA32
1946193185point mutationsingle base pair of a gene, can be harmful, not fatal, a disease for instance, only affects one amino acid33
1946193186insertions and deletionsadd or loss-causes a frame shift-can be disastrous34
1946193187Bacteria..prokaryotic cells that consists of 1 double stranded circular DNA.35
1946193188operon...promoter/operator pair that services multiple genes36
1946193189operator...a short sequence near the promoter that assists in transcription by interacting with regulatory proteins(factors)37
1946193190regulator...enhancer, DNA region that is influences transcription by interacting with specific transcription factors38
1946193191repressor...protein that prevents the binding of RNA polymerase to the promoter site39
1946193192inducer...molecule that binds to and inactivates a repressor40
1946193193pyrimidineThymine and cytosine, single ring structure, will match with a purine41
1946193194purineadenosine and guanine, double ring structure, will match with a pyrimidine42
1946193195helicaseunzips the helix of DNA to start replication and protein synthesis43
1946193196P sitethe site the polypeptide bond of the protein, A site is behind it "new ___" is bonding the amino acid from the A site, and the "old P" site release the tRNA44
1946193197DNA methylationaddition of methyl, CH3, to DNA which renders DNA inactive, ex. Barr Bodies45
1946193198virusparasitic infectious agent that can only survive on a host, only DNA and a capsid(protein coat)46
1946193199retrovirusRNA virus that carries an enzyme, reverse transcriptase, EX: HIV virus of AIDS, reverse transcription47
1946193200lytic cyclethe cell produces many viral offspring which are released from the cell and kill the host cell in the process48
1946193201lysogenic cyclethe virus falls dormant and incorporates its DNA into the host DNA as an entity(provirus). Viral DNA is reproduced every time, staying alive, never killing the host. Can enter into a lytic cycle49
1946193202plasmidscircular DNA in bacteria, with only a few genes, replicate independent of the main chromosome50
1946193203binary fissionbacteria's reproductive process, replicates DNA and pinches in half, so identical to parent51
1946193204transformationuptake of foreign DNA, use of proteins on the surface of cells that snag pieces of DNA52
1946193205Griffith's experimentbacteria Strep which is either rough(non virulent) or smooth(virulent)-->passes the virulent strain because they were transformed53
1946193206virulentstrain that contracts the illness54
1946193207bacteriophagea virus that infects bacteria, by latching on the surface of a cell and firing the DNA into the cell55
1946193208transductionmovement of genes from one cell to another by phages, specialized or specialized56
1946193209generalized transductioncreating a new cell to resistant to penicillin by a phage virus infecting and taking over a bacterial cell that contains a functional gene for resistance to penicillin57
1946193210specialized transductionvirus that is in the lysogenic cycle, resting quietly along with the other DNA of the host cell. If the new phage offspring attaches to a cell that is not penicillin resistant and injects its DNA and crossover occurs, specialized transduction occurred.58
1946193211recombinant DNAwhen DNA fragments with sticky ends reconnect with other DNA fragments. For genetic engineering to move DNA from one source to another.59

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