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Cambell's Biology Chapter 17 Flashcards

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1896878888GeneA discrete unite of hereditary information consisting of a specific nucleotide sequence in DNA0
1896878889DNAA double-stranded, helical nucleic acid molecule, consisting of nucleotide monomers with a deoxyribose sugar and the nitrogen bases (A,T,C,G)1
1896912024Nucleotide DifferencesRNA is a single strand, ribose sugar and U with A, not T. DNA is double stranded, deoxyribose and T, A, C, G.2
1896924719RNA Modifications after transcriptionImmature RNA becomes mature due to protein splicing3
1896924720mRNA...messanger RNA in the nucleus that encodes the DNA code, writes it down, has U's instead of T's, only one strand4
1896924721RNA PolymeraseAn enzyme that produces primary transcript RNA by attaching to the promoter region of the DNA, after it's unwound(by helicase).5
1896924722poly(A) TailA sequence of 50 to 250 adenine nucleotides added onto the 3' end of a pre-mRNA molecule6
18969247235' Capspecially altered nucleotide on the 5′ end of some eukaryotic primary transcripts -guanine cap which srves to protect the RNA and attach the ribosomes.7
1896924724TranslationWhen mRNA and tRNA(anticodon) translate the code, by transferring the correct amino acid for the codon(mRNA) There is a change of "language" from nucleotides to amino acids8
1896924725Protein Synthesisthe process by which amino acids are linearly arranged into proteins by mRNA writing down the code from the DNA template, tRNA transferring the correct amino acid, and then they bond to form the protein.9
1896924726Ribosome (large vs small)A molecule consisting of 2 subunits that fit together and work as 1 to build proteins according to messages in mRNA. Using mRNA as a template, it traverses codon and pairs with the right amino acid. Interacting with tRNA.10
1896924727A siteA: ribosome binding site. holds tRNA carrying amino acid for polypeptide chain11
1896924728tRNATransports specific amino acids to ribosome to add to polypeptide chain on the ribosome12
1896924729rRNAlocation where the mRNA and tRNA meet; 2 units(lg and sm)13
1896924730Start CodonThe first of the 3 nucleotide sequence that specifies, AUG, that establishes the reading frame for protein synthesis14
1896924731Aminoacyl-tRNA synthesaseAn enzyme that joins each amino acid or the to the appropriate tRNA15
1896924732Amino acidsAn organic molecule possessing both carboxyl and amino groups. Amino acids serve as the monomers of polypeptides to build a protein16
1896924733Peptidyl Transferasean enzyme that catalyzes the addition of amino acid residues to the growing polypeptide chain in protein synthesis by means of peptide bonds17
1896924734Polypeptidesingle linear chain of many amino acids, held together by peptide bonds18
1896924735Codonsa sequence of three DNA or RNA nucleotides that corresponds with a specific amino acid or stop signal during protein synthesis19
1896924736Stop Codonsnucleotide triplet within messenger RNA that signals a termination of translation. UGA, UAG, UAA20
1896924737Anticodonsa sequence of three nucleotides in a region of transfer RNA that recognizes a complementary coding triplet of nucleotides in messenger RNA during translation21
1896924738Initiation...1st step in translation of RNA. Two step process to establish exactly where translation will begin, ensuring that the mRNA codons are translated in the correct sequence of amino acids.22
1896924739Elongation...Aminoacyl tRNA brings a new amino acid to the A site. And the binding occurs due to cod an/anticodon recognition23
1896924740Termination...tells the polymerase to stop by Release Factors which bind with stop codons in the A site; add water to release the chain from final tRNA, mRNA is released and free24
1925595818promoterDNA sequence where RNA polymerase attaches and initiates transcription, contains the TATA box25
1925595819TATA boxa promoter DNA sequence26
1925595820direction for processing mRNADNA-3 to 5, mRNA-5 to 327
1925595821transcription factorsproteins that mediate the binding of RNA polymerase28
1925595822RNA splicingremoval of large portions of RNA molecule that is initially synthesized-long noncoding sequences, not continuous(split into segments)29
1925595823intronsintervening sequences that do not code-stay in the nucleus, refer to both the DNA and RNA sequences that encode them30
1925595824exonsEXIT the nucleus, because they will be coded31
1925595825wobblepairing with tRNA -can be different anticodons synonymous for a given amino acid; allows 45 rRNA molecules to service all the different types of codons on the mRNA32
1925595826point mutationsingle base pair of a gene, can be harmful, not fatal, a disease for instance, only affects one amino acid33
1925595827insertions and deletionsadd or loss-causes a frame shift-can be disastrous34
1925595828Bacteria..prokaryotic cells that consists of 1 double stranded circular DNA.35
1925595829operon...promoter/operator pair that services multiple genes36
1925595830operator...a short sequence near the promoter that assists in transcription by interacting with regulatory proteins(factors)37
1925595831regulator...enhancer, DNA region that is influences transcription by interacting with specific transcription factors38
1925595832repressor...protein that prevents the binding of RNA polymerase to the promoter site39
1925595833inducer...molecule that binds to and inactivates a repressor40
1928959012pyrimidineThymine and cytosine, single ring structure, will match with a purine41
1928959013purineadenosine and guanine, double ring structure, will match with a pyrimidine42
1928959014helicaseunzips the helix of DNA to start replication and protein synthesis43
1928959015P sitethe site the polypeptide bond of the protein, A site is behind it "new P site" is bonding the amino acid from the A site, and the "old P" site release the tRNA44
1928959016DNA methylationaddition of methyl, CH3, to DNA which renders DNA inactive, ex. Barr Bodies45
1928959017virusparasitic infectious agent that can only survive on a host, only DNA and a capsid(protein coat)46
1928959018retrovirusRNA virus that carries an enzyme, reverse transcriptase, EX: HIV virus of AIDS, reverse transcription47
1928959019lytic cyclethe cell produces many viral offspring which are released from the cell and kill the host cell in the process48
1928959020lysogenic cyclethe virus falls dormant and incorporates its DNA into the host DNA as an entity(provirus). Viral DNA is reproduced every time, staying alive, never killing the host. Can enter into a lytic cycle49
1928959021plasmidscircular DNA in bacteria, with only a few genes, replicate independent of the main chromosome50
1928959022binary fissionbacteria's reproductive process, replicates DNA and pinches in half, so identical to parent51
1928959023transformationuptake of foreign DNA, use of proteins on the surface of cells that snag pieces of DNA52
1928959024Griffith's experimentbacteria Strep which is either rough(non virulent) or smooth(virulent)-->passes the virulent strain because they were transformed53
1928959025virulentstrain that contracts the illness54
1928959026bacteriophagea virus that infects bacteria, by latching on the surface of a cell and firing the DNA into the cell55
1928959027transductionmovement of genes from one cell to another by phages, specialized or specialized56
1928959028generalized transductioncreating a new cell to resistant to penicillin by a phage virus infecting and taking over a bacterial cell that contains a functional gene for resistance to penicillin57
1928959029specialized transductionvirus that is in the lysogenic cycle, resting quietly along with the other DNA of the host cell. If the new phage offspring attaches to a cell that is not penicillin resistant and injects its DNA and crossover occurs, specialized transduction occurred.58
1928959030recombinant DNAwhen DNA fragments with sticky ends reconnect with other DNA fragments. For genetic engineering to move DNA from one source to another.59

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