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Campbell Biology 7th Edition Chapter 16 Molecular Basis of Inheritance Flashcards

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1245471045TransformationIncorporation of naked DNA into a bacteria cell.0
1245471046Chargraff's RuleAdenine to Thymine amount is proportional Cytosine to Guanine amounts and are proportional in a cell of an organism.1
1245471047origins of replicationwhere DNA replication begins.2
1245471048How do eukaryotic chromosome replication origins differ from prokaryotic?Eukaryotic may have hundreds or even thousands of replication origins, compared to single origin site for prokaryotes.3
1245471049What is the function of helicase?Unwinds DNA during DNA replication.4
1245471050What is the function of Single Stand Binding Protein?Binds to and stabilizes unwound DNA during DNA replication.5
1245471051What is the function of topoisomerase?Corrects for overwinding and high tension at the replication fork during DNA unzipping.6
1245471052What is the function of Primase?Primase is an enzyme that makes RNA primers that attach to the 5 prime end of the leading strand and lagging strand.7
1245471053What is the function of DNA polymerase 3?It adds nucleotides to the 3 prime end of the RNA primer during DNA replication in leading and lagging strands.8
1245471054What is the function of DNA polymerase 1?It removes RNA primers and replaces them with DNA on the 3 prime end of leading and lagging strands.9
1245471055What is the function of ligase?Ligase is an enzyme that joins DNA strand that replaced the RNA primer to the rest of the strand, in both the leading and lagging strand.10
1245471056Name 3 DNA repair mechanisms.1) DNA Proof reading - finds errors and corrects them as "it" moves along the strand. 2) Mismatch repair - finds matching errors, cuts out the mismatched section and DNA pol I comes in and inserts a new corrected sequence of DNA. 3) Excision repair - finds non functional damaged DNA and excises it, then DNA pol I inserts the correct DNA base sequence in 5 prime to 3 prime direction.11
1245471057What is the function of telomerase?Telomerase catalyzes the lengthening of telomeres in cells, and provides 3 prime O H hydroxyl to the RNA primer, making it serve as a template for laying down more DNA nucleotides to restore the original length of the DNA strand.12

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