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Campbell Biology 9th Edition - Chapter 12 Flashcards

The Cell Cycle

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546174835cell divisionprocess by which a cell divides into two new daughter cells
546174836cell cyclesequence of events from the production of a eukaryotic cell to the time the cell itself reproduces
546174837genomethe complete genetic material contained in an individual
546174838chromosomesthreadlike structures made of DNA molecules that contain the genes
546174839chromatingranular material visible within the nucleus; consists of DNA tightly coiled around proteins
546174840somatic cellsall the cells of your body except your sex cells
546174841gametesreproductive cells, have only half the number of chromosomes as body cells
546174842sister chromatidsidentical copies of a chromosome; full sets of these are created during the S(DNA replication) subphase of interphase
546174843centromerethe region of the chromosome that holds the two sister chromatids together during mitosis
546174844mitosisin eukaryotic cells, a process of cell division that forms two new nuclei, each of which has the same number of chromosomes
546174845cytokinesisdivision of the cytoplasm during cell division
546174846M phasethe phase of the cell cycle that includes mitosis and cytokinesis
546174847interphasethe period of the cell cycle during which the nucleus is not undergoing division, typically occurring between mitotic or meiotic divisions
546174848G1 phaseThe first growth phase of the cell cycle, consisting of the portion of interphase before DNA synthesis begins.
546174849S phaseThe synthesis phase of the cell cycle; the portion of interphase during which DNA is replicated.
546174850G2 phasestage of interphase in which cell duplicates its cytosol and organelles
546174851prophasethe replicated chromosomes, each consisting of two closely associated sister chromatids, condense. Outside the nucleus, the mitotic spindle assembles between the two centrosornes, which have replicated and moved apart.
546174852prometaphasestarts abruptly with the breakdown of the nuclear envelope. Chromosomes can now attach to spindle microtubules via their kinetochores and undergo active movement.
546174853metaphasechromosomes are aligned at the equator of the spindle, midway between the spindle poles. The kinetochore microtubules attach sister chromatids to opposite poles of the spindle.
546174854anaphasethe sister chromatids separate to form two daughter chromorosomes, each is pulled slowly toward the spindle pole it faces The kinetochore microtubules get shorter, and the spindle poles also move apart
546174855telophaselast phase of mitosis, chromosome are in two new cells and nuclear membranes start to reform
546174856mitotic spindleAn assemblage of microtubules and associated proteins that is involved in the movements of chromosomes during mitosis.
546174857centrosomeStructure present in the cytoplasm of animal cells, important during cell division; functions as a microtubule-organizing center. A centrosome has two centrioles.
546174858asterstar-shaped structure formed in the cytoplasm of a cell having fibers like rays that surround the centrosome during mitosis
546174859kinetochoreA specialized region on the centromere that links each sister chromatid to the mitotic spindle.
546174860metaphase plateAn imaginary plane during metaphase in which the centromeres of all the duplicated chromosomes are located midway between the two poles
546174861cleavage furrowThe first sign of cleavage in an animal cell; a shallow groove in the cell surface near the old metaphase plate.
546174862cell plateA double membrane across the midline of a dividing plant cell, between which the new cell wall forms during cytokinesis.
546174863origin of replicationThe specific location on a DNa strand where replication begins.. Prokaryotes typically have a single origin of replication, while eukaryotes have several per chromosome.
546174864binary fissiona form of asexual reproduction in single-celled organisms by which one cell divides into two cells of the same size
546174865cell cycle control systemA cyclically operating set of molecules in the cell that triggers and coordinates key events in the cell cycle.
546174866checkpointA control point in the cell cycle where stop and go-ahead signals can regulate the cycle.
546174867cyclinprotein that cycles in quantity as the cell cycle progresses; combines with and activates the kinases that function to promote the events of the cycle
546174868CDKsenzymes in an inactive form that are present in consistent concentrations over the cell cycle; *most significant enzyme in regulating cell cycle
546174869MPFMaturation-promoting factor (M-phase-promoting factor); a protein complex required for a cell to progress from late interphase to mitosis. The active form consists of cyclin and a protein kinase.
546174870G0 phaseA nondividing state in which a cell has left the cell cycle.
546174871growth factorone of a group of external regulatory proteins that stimulate the growth and division of cells
546174872density-dependent inhibitionThe phenomenon observed in normal animal cells that causes them to stop dividing when they come into contact with one another.
546174873anchorage dependenceThe requirement that to divide, a cell must be attached to the substratum.
546174874transformationthe process that converts a normal cell to a cancer cell
546174875malignant tumoran abnormal tissue mass that can spread into neighboring tissue and to other parts of the body; a cancerous tumor.
546174876benign tumorA mass of abnormal cells that remains at the site of origin
546174877metastasisspread of cancer cells beyond their original site in the body
546174878platelet derived growth factorsecreted by blood platelets and endothelial cells in an area of injury, this is an agent that stimulates fibroblasts to multiply and synthesize collagen

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