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Campbell Biology 9th Edition - Chapter 12 Flashcards

The Cell Cycle

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428922091cell divisionprocess by which a cell divides into two new daughter cells
428922092cell cyclesequence of events from the production of a eukaryotic cell to the time the cell itself reproduces
428922093genomethe complete genetic material contained in an individual
428922094chromosomesthreadlike structures made of DNA molecules that contain the genes
428922095chromatingranular material visible within the nucleus; consists of DNA tightly coiled around proteins
428922096somatic cellsall the cells of your body except your sex cells
428922097gametesreproductive cells, have only half the number of chromosomes as body cells
428922098sister chromatidsidentical copies of a chromosome; full sets of these are created during the S(DNA replication) subphase of interphase
428922099centromerethe region of the chromosome that holds the two sister chromatids together during mitosis
428922100mitosisin eukaryotic cells, a process of cell division that forms two new nuclei, each of which has the same number of chromosomes
428922101cytokinesisdivision of the cytoplasm during cell division
428922102M phasethe phase of the cell cycle that includes mitosis and cytokinesis
428922103interphasethe period of the cell cycle during which the nucleus is not undergoing division, typically occurring between mitotic or meiotic divisions
428922104G1 phaseThe first growth phase of the cell cycle, consisting of the portion of interphase before DNA synthesis begins.
428922105S phaseThe synthesis phase of the cell cycle; the portion of interphase during which DNA is replicated.
428922106G2 phasestage of interphase in which cell duplicates its cytosol and organelles
428922107prophasethe replicated chromosomes, each consisting of two closely associated sister chromatids, condense. Outside the nucleus, the mitotic spindle assembles between the two centrosornes, which have replicated and moved apart.
428922108prometaphasestarts abruptly with the breakdown of the nuclear envelope. Chromosomes can now attach to spindle microtubules via their kinetochores and undergo active movement.
428922109metaphasechromosomes are aligned at the equator of the spindle, midway between the spindle poles. The kinetochore microtubules attach sister chromatids to opposite poles of the spindle.
428922110anaphasethe sister chromatids separate to form two daughter chromorosomes, each is pulled slowly toward the spindle pole it faces The kinetochore microtubules get shorter, and the spindle poles also move apart
428922111telophaselast phase of mitosis, chromosome are in two new cells and nuclear membranes start to reform
428922112mitotic spindleAn assemblage of microtubules and associated proteins that is involved in the movements of chromosomes during mitosis.
428922113centrosomeStructure present in the cytoplasm of animal cells, important during cell division; functions as a microtubule-organizing center. A centrosome has two centrioles.
428922114asterstar-shaped structure formed in the cytoplasm of a cell having fibers like rays that surround the centrosome during mitosis
428922115kinetochoreA specialized region on the centromere that links each sister chromatid to the mitotic spindle.
428922116metaphase plateAn imaginary plane during metaphase in which the centromeres of all the duplicated chromosomes are located midway between the two poles
428922117cleavage furrowThe first sign of cleavage in an animal cell; a shallow groove in the cell surface near the old metaphase plate.
428922118cell plateA double membrane across the midline of a dividing plant cell, between which the new cell wall forms during cytokinesis.
428922119origin of replicationThe specific location on a DNa strand where replication begins.. Prokaryotes typically have a single origin of replication, while eukaryotes have several per chromosome.
428922120binary fissiona form of asexual reproduction in single-celled organisms by which one cell divides into two cells of the same size
428922121cell cycle control systemA cyclically operating set of molecules in the cell that triggers and coordinates key events in the cell cycle.
428922122checkpointA control point in the cell cycle where stop and go-ahead signals can regulate the cycle.
428922123cyclinprotein that cycles in quantity as the cell cycle progresses; combines with and activates the kinases that function to promote the events of the cycle
428922124CDKsenzymes in an inactive form that are present in consistent concentrations over the cell cycle; *most significant enzyme in regulating cell cycle
428922125MPFMaturation-promoting factor (M-phase-promoting factor); a protein complex required for a cell to progress from late interphase to mitosis. The active form consists of cyclin and a protein kinase.
428922126G0 phaseA nondividing state in which a cell has left the cell cycle.
428922127growth factorone of a group of external regulatory proteins that stimulate the growth and division of cells
428922128density-dependent inhibitionThe phenomenon observed in normal animal cells that causes them to stop dividing when they come into contact with one another.
428922129anchorage dependenceThe requirement that to divide, a cell must be attached to the substratum.
428922130transformationthe process that converts a normal cell to a cancer cell
428922131malignant tumoran abnormal tissue mass that can spread into neighboring tissue and to other parts of the body; a cancerous tumor.
428922132benign tumorA mass of abnormal cells that remains at the site of origin
428922133metastasisspread of cancer cells beyond their original site in the body
428927585platelet derived growth factorsecreted by blood platelets and endothelial cells in an area of injury, this is an agent that stimulates fibroblasts to multiply and synthesize collagen

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