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Campbell Biology Chapter 17 Flashcards

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6895213247A Siteone of a ribosome's three binding sites for tRNA during translation; the A site holds the tRNA carrying the next amino acid to be added to the polypeptide chain. (A stands for aminoacyl tRNA.)0
6895213248Alternative RNA Splicinga type of eukaryotic gene regulation at the RNA-processing level in which different mRNA molecules are produced from the same primary transcript, depending on which RNA segments are treated as exons and which as introns1
6895213249Anticodona nucleotide triplet at one end of a tRNA molecule that base-pairs with a particular complementary codon on an mRNA molecule2
6895213250Codona three-nucleotide sequence of DNA or mRNA that specifies a particular amino acid or termination signal; the basic unit of the genetic code3
6895213251Exona sequence within a primary transcript that remains in the RNA after RNA processing; also refers to the region of DNA from which this sequence was transcribed4
6895213252Frameshift MutationA mutation occurring when nucleotides are inserted in or deleted from a gene and the number inserted or deleted is not a multiple of three, resulting in the improper grouping of the subsequent nucleotides into codons5
6895213253Gene Expressionthe process by which information encoded in DNA directs the synthesis of proteins or, in some cases, RNAs that are not translated into proteins and instead function as RNAs6
6895213254Insertiona mutation involving the addition of one or more nucleotide pairs to a gene7
6895213255Introna noncoding, intervening sequence within a primary transcript that is removed from the transcript during RNA processing; also refers to the region of DNA from which this sequence was transcribed8
6895213256Messenger RNA (mRNA)a type of RNA, synthesized using a DNA template, that attaches to ribosomes in the cytoplasm and specifies the primary structure of a protein. (In eukaryotes, the primary RNA transcript must undergo RNA processing to become mRNA.)9
6895213257Missense Mutationa nucleotide-pair substitution that results in a codon that codes for a different amino acid10
6895213258Mutagena chemical or physical agent that interacts with DNA and can cause a mutation (Ex: UV light, tanning bed)11
6895213259Mutationa change in the nucleotide sequence of an organism's DNA or in the DNA or RNA of a virus12
6895213260Nonsense Mutationa mutation that changes an amino acid codon to one of the three stop codons, resulting in a shorter and usually nonfunctional protein13
6895213261Nucleotide-Pair Substitutiona type of point mutation in which one nucleotide in a DNA strand and its partner in the complementary strand are replaced by another pair of nucleotides14
6895213262P Siteone of a ribosome's three binding sites for tRNA during translation; the P site holds the tRNA carrying the growing polypeptide chain. (P stands for peptidyl tRNA.)15
6895213263Point Mutationa change in a single nucleotide pair of a gene16
6895213264Poly-A Taila sequence of 50-250 adenine nucleotides added onto the 3′ end of a pre-mRNA molecule17
6895213265Polyribosome (Polysome)a group of several ribosomes attached to, and translating, the same messenger RNA molecule The whole picture is a polyribosome18
6895213266Primary Transcriptan initial RNA transcript from any gene; also called pre-mRNA when transcribed from a protein-coding gene. This is what you get right after the slicing occurs.19
6895213267Promotera specific nucleotide sequence in the DNA of a gene that binds RNA polymerase, positioning it to start transcribing RNA at the appropriate place20
6895213268Reading Frameon an mRNA, the triplet grouping of ribonucleotides used by the translation machinery during polypeptide synthesis21
6895213269Ribosomal RNA (rRNA)RNA molecules that, together with proteins, make up ribosomes; the most abundant type of RNA22
6895213270Ribosomea complex of rRNA and protein molecules that functions as a site of protein synthesis in the cytoplasm; consists of a large and a small subunit. In eukaryotic cells, each subunit is assembled in the nucleolus; see also nucleolus23
6895213271RNA Processingmodification of RNA primary transcripts, including splicing out of introns, joining together of exons, and alteration of the 5′ and 3′ ends24
6895213272RNA Splicingafter synthesis of a eukaryotic primary RNA transcript, the removal of portions of the transcript (introns) that will not be included in the mRNA and the joining together of the remaining portions (exons)25
6895213273Signal Peptidea sequence of about 20 amino acids at or near the leading (amino) end of a polypeptide that targets it to the endoplasmic reticulum or other organelles in a eukaryotic cell26
6895213274Signal-Recognition Particle (SRP)a protein-RNA complex that recognizes a signal peptide as it emerges from a ribosome and helps direct the ribosome to the endoplasmic reticulum (ER) by binding to a receptor protein on the ER27
6895213275Silent Mutationa nucleotide-pair substitution that has no observable effect on the phenotype; for example, within a gene, a mutation that results in a codon that codes for the same amino acid28
6895213276Start Pointin transcription, the nucleotide position on the promoter where RNA polymerase begins synthesis of RNA29
6895213277TATA Boxa DNA sequence in eukaryotic promoters crucial in forming the transcription initiation complex30
6895213278Template Strandthe DNA strand that provides the pattern, or template, for ordering, by complementary base pairing, the sequence of nucleotides in an RNA transcript31
6895213279TerminatorIn bacteria, a sequence of nucleotides in DNA that marks the end of a gene and signals RNA polymerase to release the newly made RNA molecule and detach from the DNA. Same as STOP but for Bacteria32
6895213280Transcriptionthe synthesis of RNA using a DNA33
6895213281Transcription Factora regulatory protein that binds to DNA and affects transcription of specific genes34
6895213282Transcription Unita region of DNA that is transcribed into an RNA molecule35
6895213283Transfer RNA (tRNA)an RNA molecule that functions as a translator between nucleic acid and protein languages by carrying specific amino acids to the ribosome, where they recognize the appropriate codons in the mRNA36
6895213284TranslationThe synthesis of a polypeptide using the genetic information encoded in an mRNA molecule; there is a change of "language" from nucleotides to amino acids37
6895213285Triplet Codea genetic information system in which sets of three-nucleotide-long words specify the amino acids for polypeptide chains38
6895213286Wobbleflexibility in the base-pairing rules in which the nucleotide at the 5′ end of a tRNA anticodon can form hydrogen bonds with more than one kind of base in the third position (3′ end) of a codon39

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