Vocabulary: aerobic respiration, anaerobic respiration, fermentation, oxidation, reduction, reducing agent, oxidizing agent, redox reaction, electron transport chain, NAD (nicotinamide adenine dinucleotide), glycolysis, Kreb cycle (citric acid cycle), oxidative phosphorylation, substrate-level phosphorylation, chemiosmosis, ATP synthase, cytochromes, proton-motive force, obligate aerobe, obligate anaerobe, facultative anaerobe, beta oxidation, biosynthesis
Objectives: After attending lectures and studying the chapter, the student should be able to:
1. Define cellular respiration.
a. State which organisms undergo cellular respiration.
b. Distinguish between the site of cellular respiration in prokaryotic cells and in eukaryotic cells.
c. Distinguish between the terms aerobic and anaerobic.
d. Write the general chemical equation for aerobic cellular respiration.
e. Write the general chemical equation for lactic acid fermentation and state which organisms can undergo this process.
f. Write the general chemical equation for alcohol fermentation and state which organisms can undergo this process.
2. Relating to cellular energy:
a. Explain the chemical energy relationship between glucose and ATP.
b. Explain the chemical energy role of ATP in driving cellular reactions.
c. Describe the structure of ATP, ADP, and AMP.
d.Explain why ATP is considered the "energy currency" of the cell and glucose is not.
e. State how many ATPs are produced from 1 glucose molecule during:
* aerobic cellular respiration in prokaryotic cells
* aerobic cellular respiration in eukaryotic cells
* fermentation
3. Describe the making of ATP through substrate-level phosphorylation.
4. Relating to oxidative phosphorylation (electron transport chain + chemiosmosis):
a. Define oxidation and reduction and describe the redox reactions of an electron transport chain.
b. Relate the redox reactions of an electron transport chain to the active transport of
hydrogen ions (H+) across a membrane.
c. Relate the active transport of H+ ions across a membrane to the formation of an electrochemical gradient.
d. Relate the electrochemical gradient to the facilitated diffusion of H+ ions across a
membrane.
e. Relate facilitated diffusion of H+ ions through the ATP synthase protein channel to
the making of ATP.
5. Relating to aerobic cellular respiration:
a. Describe the molecules ATP and NADH and distinguish between the different energy-storing roles of each.
b. Describe the process of glycolysis, including the major molecules involved and the
energy-storing molecules produced.
c. Describe the process of the transition reaction, including the major molecules involved
and the energy-storing molecules produced.
d. Describe the process of the Krebs cycle, including the major molecules involved and the energy-storing molecules produced, and explain why the Krebs cycle is considered a cycle.
e. Describe the roles of NADH, FADH2, and O2 in the electron transport chain part of
oxidative phosphorylation.
f. Show the relationship between the electron transport chain, active transport, and facilitated diffusion in the oxidative phosphorylation process of making ATP.
g. State the specific locations of glycolysis, the transition reaction, the Krebs cycle, and
the oxidative-phosphorylation process in eukaryotic cells.
h. State the specific locations of glycolysis, the transition reaction, the Krebs cycle, and
the oxidative-phosphorylation process in prokaryotic cells.
i. State the number of ATPs produced during glycolysis, the transition reaction, the Krebs
cycle, and the oxidative-phosphorylation process.
j. Explain why aerobic cellular respiration results in 36 ATPs per glucose in eukaryotic cells and 38 ATPs per glucose in prokaryotic cells.
k. Relate glycolysis to lactic acid fermentation and alcohol fermentation.
6. Describe how organic molecules other than glucose (specifically proteins, fats, and
nucleic acids) can be a source of energy by being broken down and used during glycolysis,
the transition reaction, or the Krebs cycle.
5264873916 | Aerobic | in the presence of oxygen | 0 | |
5264873917 | Glycolysis | first step in CR; produces net 2 ATP, 2 NADH, 2 pyruvates | 1 | |
5264873918 | Electron Transport Chain | 3rd step in CR; occurs on the inner membrane of the mitochondria.; transfers H from NADH and FADH2 to oxgyen; creates 34 ATP | ![]() | 2 |
5264873919 | oxidation | partial or complete loss of electrons; occurs to glucose during CR | 3 | |
5264901638 | redox reactions | involves the complete or partial transfer of electrons from one reactant to another | 4 | |
5264903086 | reduction | partial or complete gain of electrons; occurs to oxygen in CR | 5 | |
5264905379 | facultative | organism that can live in either aerobic or anaerobic environments | 6 | |
5264907925 | obligate aerobe | organism that must live in the presence of oxygen | 7 | |
5264909142 | obligate anaerobe | organism that must live in an oxygen free environment | 8 | |
5264912503 | Krebs Cycle | 2nd step of CR; catabolic pathway that oxidizes acetyl CoA producing 2 AATP, 6 NADH, 2 FADH2, and 4 CO2 | 9 | |
5264919115 | Acetyl CoA | compound that enters the Krebs Cycles; formed from the oxidation of pyruvate during the "transition step" | 10 | |
5264922094 | fermentation | anaerobic catabolism of organic nutrients | 11 | |
5264926434 | alcoholic | fermentation that converts pyruvate into ethanol; performed by yeast and bacteria | 12 | |
5264928867 | lactic acid | fermentation that converts pyruvate into lactic acid | 13 | |
5264939415 | substrate - level | phosphorylation of ADP as a result of enzyme controlled pathways | 14 | |
5264940783 | oxidative | phosphorylation as a result of chemiosmosis and the ETC | 15 | |
5264943651 | chemiosmosis | coupling of exergonic electron flow down the ETC to the endergonic production of aTP | 16 | |
5264946434 | ATP synthase | enzyme in the inner membrane that drives the oxidative phosphorylation of ATP during the ETC | 17 | |
5264951823 | Cellular respiration | an ATP producing catabolic pathway in which the final electron acceptor is oxygen; complete degradation of sugars producing ATP | 18 | |
5264956475 | Anaerobic respiration | occurs without oxygen; includes glycolysis and fermentation | 19 | |
5264961516 | Matrix | in the mitochondria; site of the Krebs cycle | 20 | |
5264962751 | inner membrane | in the mitochondria; site of ETC and oxidative phosphorylation | 21 | |
5264968157 | cristae | folds of the inner membrane of the mitochondria; increases SA for the ETC | 22 | |
5264972838 | cytosol | where glycolysis and fermentation occurs | 23 |