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Chapter 16 The Molecular Basis of Inheritance Flashcards

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688635747transformationA change in genotype and phenotype due to the assimilation of external DNA by a cell.0
688635748bacteriophagesA virus that infects bacteria; also called a phage.1
688635749semiconservative modelType of DNA replication in which the replicated double helix consists of one old strand, derived from the old molecule, and one newly made strand.2
688635750origins of replicationSite where the replication of a DNA molecule begins, consisting of a specific sequence of nucleotides.3
688635751replication forkA Y-shaped region on a replicating DNA molecule where new strands are growing.4
688635752DNA polymerasesAn enzyme that catalyzes the formation of the DNA molecule.5
688635753lagging strandA discontinuously synthesized DNA strand that elongates by means of Okazaki fragments, each synthesized in a 5' to 3' direction away from the replication fork.6
688635754leading strandThe new continuous complementary DNA strand synthesized along the template strand in the mandatory 5' to 3' direction.7
688635755Okazaki fragmentsSmall fragments of DNA produced on the lagging strand during DNA replication, joined later by DNA ligase to form a complete strand.8
688635756primaseAn enzyme that joins RNA nucleotides to make the primer using the parental DNA strand as a template.9
688635757helicaseAn enzyme that untwists the double helix at the replication forks, separating the two parental strands and making them available as template strands.10
688635758topoisomeraseA protein that functions in DNA replication, helping to relieve strain in the double helix ahead of the replication fork.11
688635759single-strand binding proteinBinds to and stabilizes single-stranded DNA until it can be used as a template.12
688635760nucleaseA DNA cutting enzyme that excises damaged DNA.13
688635761telomeresRepeated DNA sequences at the ends of eukaryotic chromosomes.14
688635762telomeraseAn enzyme that catalyzes the lengthening of telomeres in eukaryotic germ cells.15
688635763Watson and CrickDeveloped the double helix model of DNA.16
688635764Hersey-Chase ExperimentDevised an experiment that showed that only the DNA of T2 phages enters a bacterial cell during infection.17
688635765Frederick GriffithThis person discovered transformation during an experiment that involved injecting mice with smooth S cells, rough R cells, heat-killed S cells, and heat-killed S cells with living R cells.18
688635770Erwin ChargaffDiscovered that DNA composition varies, but the amount of adenine is always the same as thymine and the amount of cytosine is always the same as guanine.19
688635771Meselson & StahlDetermined that DNA replication is semiconservative.20

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