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| 3837682254 | Who was Doña Marina? | A young woman who helped Cortés in the conquest of Mexico by acting as a diplomat, and reporting her findings to Cortés. | 0 | |
| 3837712560 | What aided the Spanish conquest of Mexico? | Epidemic diseases. | 1 | |
| 3837723562 | Who were the Taíno? | A Caribbean tribe who were the first indigenous people to come in contact with Christopher Columbus. | 2 | |
| 3837743853 | What was the island of Hispaniola used for? | The base of Spanish operations in the Caribbean. | 3 | |
| 3837755528 | The Caribbean region offered no silks or spices for the European market, what was a solution for the Spanish settlers? | Mining gold. | 4 | |
| 3837766253 | What was the encomienda? | System that gave spanish settlers the right to compel the indigenous peoples of the Americas to work in the mines or fields. | 5 | |
| 3837788110 | Spanish settlers launched raiding parties to replace workers lost from what? | Smallpox. | 6 | |
| 3837824298 | French, English, and Dutch settlers wanted to establish plantations in the Caribbean, but native populations were extinct and they were in need of laborers. Where did they import many slaves from? | Africa. | 7 | |
| 3837843115 | Who was Motezcuzoma? | Aztec emperor who was brought down in 1520 by Cortés. | 8 | |
| 3837875632 | Who was Atahualpa? | Inca ruler who was killed by Pizarro and his men. | 9 | |
| 3837895344 | Viceroys were...? Who checked their authority? | The kings' representatives in the Americas. Audiencias checked their authority. | 10 | |
| 3837913468 | True or False: Spanish administration in the Americas was a ragged affair. | True. | 11 |
