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Chapter 3: Cellular Form and Function Flashcards

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5940562994Cytologyscientific study of cells0
5940572624Louise Pasteurdemonstrated " all cells arise from other cells" Refuted idea of spontaneous generation1
5940581510Cell TheoryAll organisms composed of cells and cell products Cell is the simplest structural and functional unit of life An organisms structure/ function due to activities in cells Cells come only from pre-existing cells2
5940603470How many types of cells are in the human body?200 types with varied shapes3
5940605499Squamousthin, flat, scaly4
5940610758Cuboidalsquarish looking5
5940621634Columnartaller than wide6
5940621635Polygonalhaving irregularly angular shapes with four, five, or more sides7
5940621636Stellatestar-shaped8
5940625168Spheroid to Ovoidround to oval9
5940625169Discoiddisc-shaped10
5940625170Fusiformthick in the middle and tapered towards the ends11
5940627254Fibrousthread-like12
5940648682What are the size of most cells?10-15 micrometers in diameter13
5940652633Size of egg cells?about 100 micrometers14
5940654109Size of nerve cells?Over 1 metre long15
5940655291Limit on cell size:an overly large cell cannot support itself, may rupture For a given increase in diameter, volume increases more than surface area16
5940668161What happens if cell is too big?Oxygen will not get through (diffusion) because volume is too big17
5940677116Light Microscope reveals:plasma membrane, nucleus, and cytoplasm18
5940681802Transmission Electron Microscope reveals:improved resolution ( ability to reveal detail)19
5940688225Scanning Electron Microscope:Reveals even more improved resolution. The best.20
5940697233Plasma Cell MembraneSurrounds cell, defines boundaries Made of Proteins and Lipids21
5940703311CytoplasmContains: organelles, cytoskeleton, inclusions, cytosol22
5940710154Extracellular Fluid ECFFluid outside of cells includes tissue (interstitial) fluid23
5940722760Plasma Membrane: AnatomyAppears as pair of dark parallel line when viewed with EM Has intracellular and extracellular faces24
5940731749Plasma Membrane: FunctionsDefines cell boundaries Governs interactions with other cells Controls passage of materials in and out of cell25
5940790462What percent of membrane molecules are lipids?98%26
5940794180Phospholipids75% of membrane lipids are phospholipids27
5940811589Amphipathic molecules arranged in a bilayerhydrophilic phosphate heads face water on each side of membrane hydrophobic tails are directed toward the centre, avoiding water Drift laterally, keeping membrane fluid28
5940819001Cholesterol20% of the membrane lipids Holds phospholipids still and can stiffen membrane29
5940824313Glycolipid (Glycogen)5% of membrane lipids phospholipids with short carbohydrate chains on extracellular face contributes to glycocalyx - carbohydrate coating on cell surface30
5940850424Membrane Proteins:2% of the molecules but 50% of the weight of membrane31
5940857962Integral ProteinsTransmembrane proteins pass completely through Hydrophilic regions contact cytoplasm, extracellular fluid Hydrophobic regions pass through lipid of the membrane Some drift in membrane, others anchored to cytoskeleton32
5940887184Peripheral ProteinsAdhere to one face of the membrane (do not penetrate it) Usually tethered to cytoskeleton33
5940908221ReceptorsBind chemical signals34
5940913902EnzymesCatalyze reactions including digestion of molecules, production of second messengers35
5940944024Channel Proteinsallow hydrophilic solutes and water to pass through membrane Crucial to nerve and muscle function36
5940950421Not all channel proteins are always open...Some channel proteins are always protein whereas some are gated37
5940956137Ligand Gated ChannelsRespond to chemical messengers38
5940958028Voltage-gated channelsrespond to charge changes39
5940961343Mechanically gated channelsRespond to physical stress on cell40
5940987674CarriersBind solutes and transfer them across membrane Pumps: carriers that consume ATP41
5941021730Cell Identity MarkersGlycoproteins acting as identification tags42
5941023089Cell Adhesion moleculesmechanically link cell to extracellular material43
5941028201Second Messenger System1. Chemical first messenger (epinephrine) binds to a surface receptor 2. Receptor activates G protein 3. G protein relays signal to adenylate cyclase which coverts ATP to cAMP (2nd messenger) 4. cAMP activates cytoplasmic kinases 5. kinases add phosphate groups to other enzymes turning some on and others off44
5941065014kinaseAn enzyme that phosphorylates something else. Kinases are frequently used in regulatory pathways, phosphorylating other enzymes. ACTIVIATING PROTEIN45
5941055141G ProteinsUp to 60% of drugs work through G proteins and second messengers46
5941076341Amplificationfrom 1 ligand to 1 million cAMP47
5941108986The GlycocalyxFuzzy coat external to plasma membrane Carbohydrate moieties of glycoproteins and glycolipids Unique in everyone but identical twins48
5941120893The Glycocalyx Functionsprotection cell adhesion immunity to infection defence agains cancer development transplant compatibility fertilization embryonic49
5941131669Microvilliextension of membranes ( 1 -2 microns) gives 15-40 times more surface area Best developed in cells specialized in absorption On some absorptive cells they are very dense and appear as"brush border" Some contain Actin filaments that are tugged toward centre of cell to milk absorbed contents of cell50
6000443647CiliaHair like processes 7-10 microns single nonmotile primary cilium found on nearly every cell cells antenna for monitoring nearby conditions helps with balance in inner ear light detection in retina51
6000466609Multiple non motile ciliafound sensory cells of nose52
6000468124ciliopathiesdefects in structure/function of cilia53
6000469543motile ciliafound in respiratory tract, uterine tubes, ventricles of brain, ducts of testes beat in waves sweeping materials across surface in one direction54
6000475704axonemecore of motile cilia 9+2 structure of microtules 2 central microtubules followed by ring of nine pairs uses energy from atp55
6000513923Chlorine pumpsproduces saline layer that cilia beats in56
6000518761Flagellasperm tail whip like structure with axoneme57
6000523337movement of flagellaundulating, snakelike, corkscrew fasion58
6000529680pseudopods anatomycytoplasm filled extension of the cell varying shape from fine, filamentous to blunt finger like processes.59
6000539154pseudopods functionsused for cellular locomotion capturing foreign particles60
6000541934examples of psedopodsamoeba, neutrophils, macropages61
6000578833cell membrane is barrier and gateway between the cytoplasm and ECF isselectively permeable62
6000582942FiltrationParticles are driven through membrane by physical force63
6000624554Simple DiffusionNet movement of parties from an area of high concentration to an area of low concentration64
6000643911Factors affecting simple diffusionhigh temp, faster diffusion high weight, lower diffusion higher concentration diff, faster diffusion membrane SA, higher SA, faster diffusion membrane permeability, higher rate,65
6000656729OsmosisFlow of water from one side of a selectively permeable membrane to the other water moves down water concentration66
6000667093osmotic imbalances underliediarreah, constipation, edema67
6000668799aquaphorinschannel proteins in channel membranes specialized for H20 passage.68
6000672158Osmotic Pressure - Hydrostic pressurerequired to stop osmosis increases as amount of non permeating solute rises69
6000681745Reverse osmosisprocess of applying mechanical pressure to override osmotic pressure allows purification of water70
6000688664Osmolaritynumer of osmoses per litre of solution71
6000695699osmolalitynumber of osmoles of solute per kg of water72
6000699817Tonicityability of a solution to affect fluid volume and pressure in cell`73
6000709241Hypotonic solutioncauses cell to absorb water and swell concentration of non permeating solute is lowers than ICF74
6000712222hypertonic solutioncell loses water and shrivels [non permeating solutes] higher than ICF75
6000715483Isotonic solutioncauses no change in cell volume concentration on non permeating solutes is equal to ICF76
6000724684carrier mediated transporttransport protein in membrane carry solutes into or out of cell/organelle77
6000728943Specificitytransport proteins are specific for particular solutes78
6000759322SaturationAs solute concentration rises the rate of transport rises but only to a point: transport maximum79
60007655003 Types of carriersuniport, symport and antiport80
6000766823Uniportcarries only 1 type of solute81
6000768633symportcarroes 2 or more solutes82
6000768634antiportcarries 2 or more solutes in opposite direction83
6000772985Facilitated Transportcarrier moves solute down its concentration gradient ( no ATP consumed)84
6000792887Primary Active transportcarrier moves solute up its concentration gradient ( requires ATP) ex. uniport, antiport85
6000798189Sodium Potassium pumpA special transport protein in the plasma membrane of animal cells that transports sodium out (lower con.) of the cell and potassium (higher con.) into the cell against their concentration gradients.86
6000807288Secondary Active Transportcarrier moves solute through membrane but only uses ATP indirectly87
6000819191SGLTThis transporter is involved in symport of sodium and monosaccharides88
6000829531Vesicular transportTransport of (bulk) large particles and macromolecules across plasma membranes bubble like enclosure of membrane89
6000833242EndocytosisA process in which a cell engulfs extracellular material through an inward folding of its plasma membrane.90
6000834567PhagocytosisCell eating - engulfing large particles ex. pseudopods, phagosomes, macrophages91
6000838676pinocytosiscell drinking - takes in droplets of ECF contains molecules useful in cells92
6000844035receptor mediated endocytosisThe movement of specific molecules into a cell by the inward budding of membranous vesicles containing proteins with receptor sites specific to the molecules being taken in; enables a cell to acquire bulk quantities of specific substances.93
6000884766exocytosisProcess by which a cell releases large amounts of material utizile motor proteins energized by ATP94
6000887433transcytosisReceptor mediated transport from one side of the cell to another95
6000898786Cytoskeleton Structuremade up of three types of protein fibers: microtubules, intermediate filaments, and microfilaments. Network of internal scaffolding throughout the cell.96
6000907531Cytoskeleton function1. maintains cell shape 2.aids in cell movement 3. holds organelles in position97
6000919689organellesStructures specialized to perform distinct processes within a cell.98
6000922113nucleusA part of the cell containing DNA and RNA and responsible for growth and reproduction99
6000924801nucleus structuredouble membrane (nuclear envelope) nuclear lamina (nuclear envelope 'cavity' nuceloplasm (materials in nucleus) chromatin (composed of dna/protein) nucleolus (contains ribosomes)100
6000948872Rough Endoplasmic reticulum structureparallel flattened sacs covered with ribosome continuous with outer layer of nuclear envlp.101
6000962795Rough ER Functionproduces phospholipids/ proteins of the PM synthesize proteins that are packaged in other organelles or secreted from cell102
6001009530Smooth ER StructureTubules and vesicles that form a network with no ribosomes attached.103
6001007579Smooth ER FunctionSynthesis of lipids, phospholipids and steroid sex hormones-help detoxify drugs and poisons (liver cells).104
6001014853Ribosomes structuresmall granules of protein and DNA found in nucleoli, cytosol and on outer surface of rough ER105
6001019640ribosome functionthey read coded genetic messages (mRNA) and assemble amino acids into proteins specified by the code106
6001028286Golgi Complex structuresmall system of cisternae107
6001032623golgi complex functionsynthesizes carbs and puts finishing touches on protein synthesis -modifies, packages, and sorts newly synthesized proteins for secretion, inclusions in new plasma membrane, or lysosomal enzyme synthesis108
6001038778lysosomespackage of enzymes bound by a membrane109
6001041476lysosome function• function as an intracellular digestion system, processing material ingested by the cell or worn110
6001043373autophagydigestion of cells surplus organelles111
6001049196autolysisself-digestion occurring in plant and animal tissues, particularly after they have ceased to function properly112
6001051321peroxisomesresembles lysosomes but contain different enzymes and are produced by ER abudundant in liver113
6001056967proteosomeshollow cyclindrical organelle that disposes of surplus proteins114
6001063147mitochondriaCalled the powerhouse of the cell. Where a cell get's all it's energy from. synthesizes ATP.115
6001069989centriolesa minute cylindrical organelle near the nucleus in animal cells, occurring in pairs and involved in the development of spindle fibers in cell division.116
6001075797inclusionsstored glycogen granules, crystals, pigments, and so on117

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