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Chapter 8: An Introduction to Metabolism

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94065189Metabolic PathwaysA series of chemical reactions that either builds a complex molecule or breaks down a complex molecule into simpler compounds
94065190Catabolic PathwaysA metabolic pathway that releases energy by breaking down complex molecules to simpler compounds
94065191Anabolic PathwaysA metabolic pathway that synthesizes a complex molecule from simpler compounds
94065192Kinetic EnergyThe energy of motion, which is directly related to the speed of that motion. Moving matter does work by imparting motion to other matter
94065193Thermal EnergyThe totall amount of kinetic energy due to molecular motion in a body of matter. Heat is energy in its most random form
94065194Potential EnergyThe energy stored by matter as a result of its location or spatial arrangement
94065195Chemical EnergyEnergy stored in the chemical bonds of molecules; a form of potential energy
94065196First Law of ThermodynamicsThe principle of conservation of energy. Energy can be transferred and transformed, but it cannot be created or destroyed
94065197EntropyA quantitative measure of disorder of randomness, symbolized by 'S'
94065198Second Law of ThermodynamicsThe principle wheerby every energy transfer or transformation increases the entropy of the universe. Ordered forms of energy are at least partly converted to heat, and in spontaneous reactions, the free energy of the system also decreases
94065199Exergonic ReactionA spontaneous chemical reaction, in which there is a net release of free energy
94065200Endergonic ReactionA nonspontaneous chemical reaction, in which free energy is absorbed from the surroundings
94065201Energy CouplingIn cellular metabolism, the use of energy released from an exergonic reaction to drive an endergonic reaction
94065202ATPA cluster of several membrane proteins found in the mitochondrial crista tat function in chemiosmosis with adjacent electron trasport chains, using the energy of a hydrogen ion concentration gradient to make ATP. ATP synthases provide a port through which hydrogen ions diffuse into the matrix of a mitochondrion.
94065203PhosphorylatedReferring to a molecule that has been the recipient of a phosphate group
94065204CatalystA chemical agent that changes the rate of a reaction without being consumed by the reraction
94065205EnzymeA protein serving as a catalyst, a chemical agent that changes the rate of a reaction without being consumed by the reaction
94065206Activation EnergyThe amount of energy that reactants must absorb before a chemical reaction will start
94065207SubstrateThe reactant on which an enzyme works
94065208Enzyme-Substrate ComplexA temporary complex formed when an enzyme binds to its substrate molecule(s)
94065209Active SiteThe specific portion of an enzyme that attaches to the substrate by means of weak chemical bonds
94065210Induced FitThe change inshape of the active site of an enzyme so that it binds more snugly to the substrate, induced by entry of the substrate
94065211CofactorAny nonprotein molecule or ion that is required for the proper funcitoning of an enzyme. They can be permanently bound to the active site or may bind loosely with the substrate during catalysis
94065212CoenzymeAn organic molecule serving as a cofactor. Most vitamins funciton as ... in important metabolic reactions
94065213Competitive InhibitorA substance that reduces the activity of an enzyme by entering the active site in place of the substrate whose structure it mimics
94065214Noncompetitive InhibitorA substance that reduces the activity of an enzyme by binding to a location remote from the active site, changing its conformation so that it no longer binds to the substrate
94065215Allosteric RegulationThe binding of a molecule to a protein that affects the function of the protein at a different site
94065216CooperativityAn interaction of the constituent subunits of a protein whereby a conformational change in one subunitt is transmitted to all the others
94065217Feedback InhibitionA method of metabolic control in which the end product of a metabolic pathway acts as an ingibitor of an enzyme within that pathway
94067716MetabolismThe emergent property of life that arises from interactions between molecules within the orderly environmentof the cell

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